Agency for Science, Technology and Research

Answers to 1st issue quiz

Bold text indicates Nobel Laureates with some association with Singapore.

1 Rolf M. Zinkernagel Discoveries concerning the specificity of the cell mediated immune defence
2 Arthur Kornberg Discovery of the mechanisms in the biological synthesis of ribonucleic acid and deoxyribonucleic acid
3 James Watson Discoveries concerning the molecular structure of nucleic acids and its significance for information transfer in living material
4 Sydney Brenner Discoveries concerning 'genetic regulation of organ development and programmed cell death'
5 Stanley B. Prusiner Discovery of Prions - a new biological principle of infection
6 David Baltimore Discoveries concerning the interaction between tumour viruses and the genetic material of the cell
7 Barbara McClintock  Discovery of mobile genetic elements.
8 Kary B. Mullis Invention of the polymerase chain reaction (PCR) method.
9 Christiane Nusslein-Volhard Discoveries concerning the genetic control of early embryonic development
10 Frederick Sanger   Won the Nobel Prize twice in Chemistry
11 Linus Carl Pauling  Won the Nobel Prize twice - in Chemistry and Peace
12 Leland Hartwell, Paul Nurse Discoveries of key regulators of the cell cycle

Dr. David Baltimore is a member of Singapore’s International Advisory Council for the Biomedical Sciences. Members of this Council provide advice crucial for the success of Singapore’s Biomedical Sciences Initiative.

Dr. Sydney Brenner is Chairman of the Biomedical Research Council (BMRC) Board. The latter also heads a group at the Institute of Molecular and Cell Biology (IMCB). That group was part of the international consortium that sequenced the pufferfish genome in 2002.

Dr. James Watson visited Singapore and gave a lecture at the IMCB in 1997. Sir Paul Nurse, Prof. Leland Hartwell and Prof. Arthur Kornberg visited more recently (in 2002) as part of the BMRC’s Distinguished Visitor Programme.

Dr. Rolf Zinkernagel was a co-organiser of the Singapore-based Novartis Institute of Tropical Diseases (NITD’s) Inaugural Symposium on Dengue Fever and Tuberculosis in January 2003. He and Dr. Brenner remain members of NITD’s Scientific Advisory Board. The NITD will be moving to the Biopolis in 2004.