Past Calls
Past calls for proposals include:
- BMRC-NMRC JOINT GRANT CALL (2008)
- SINGAPORE STEM CELL CONSORTIUM (SSCC) 2008 GRANT CALL
- SINGAPORE IMMUNOLOGY NETWORK (SIgN) 2008 GRANT CALL
- JOINT SBIC-SIGN (2008) GRANT CALL
- SINGAPORE INSTITUTE FOR CLINICAL SCIENCES (SICS) 2008 GRANT CALL
- Singapore Bioimaging Consortium (SBIC) 3rd Grant Call (2007) - Results
- Joint SBIC - SSCC Grant Call (2007) - Results
- BMRC - NMRC Joint Grant Call (2007) - Results
- Singapore Immunology Network (SigN) Grant Call (2007) - Results
- Singapore Immunology Network (SIgN) Grant Call (2006) - Results
- Singapore Bioimaging Consortium (SBIC) 2nd Grant Call (2006) - Results
- BMRC - NMRC Joint Grant Call (2006) - Results
- Singapore Stem Cell Consortium (SSCC) Grant Call (2006) - Results
- Singapore Bioimaging Consortium (SBIC) 1st Grant Call (2005) - Results
- BMRC 4th Grant Call (2005) - Results
- BMRC 3rd Grant Call (2004) - Results
- BMRC - JDRF Joint Grant Call (2004) - Results
- SARS Grant Call (2003) - Results
BMRC-NMRC Joint Grant Call (2008)
RESULTS
|
S/N
|
Title
|
Host Institution
|
Principal Investigator
|
|
1
|
Dissecting Molecular Architectures and Roles of Adherens Junctions in Cell Adhesion and Tissue Remodelling with Electron Tomography
|
NUS
|
He Wanzhong
|
|
2
|
mTOR as the molecular target for modulation of autophagy, necrosis and tumorigenesis
|
NUS
|
Shen Han Ming
|
|
3
|
Developing chemical and enzymatic protein synthesis methods for protein structure-function study - application to histone proteins
|
NTU
|
Liu Chuan-Fa
|
|
4
|
Alternative splicing as molecular switch to regulate Cav2.1 channel function in synaptic excitability
|
NUS
|
Soong Tuck Wah
|
|
5
|
The role of SARM in infection: mechanisms of action and interaction partners
|
NUS
|
Ding Jeak Ling
|
|
6
|
Rational design of a hypoallergenic major dust mite allergen for allergy immunotherapy
|
NUS
|
Chua Kaw Yan
|
|
7
|
Understanding the molecular basis of red blood cell selection by malaria merozoites
|
NTU
|
Peter Rainer Preiser
|
|
8
|
Establishment of medakafish as a lower vertebrate model for analysis of primordial germ cell development
|
NUS
|
Hong Yunhan
|
|
9
|
Defining the structural traits of subunits D and E of the biological energy producer A1AO ATPsynthase
|
NTU
|
Gerhard Grüber
|
|
10
|
Spatiotemporal Imaging of Mechano-Sensing by the Src Family Kinase Substrate p130Cas
|
NUS
|
Yasuhiro Sawada
|
|
11
|
Resolving fundamental gaps in our knowledge regarding the function of parkin and its role in Parkinson’s disease
|
NNI
|
Lim Kah Leong
|
|
12
|
Synthesis and evaluation of planar pentavalent ligands targeting dimeric interface of serum amyloid P component for the therapeutic elimination of Alzheimer's disease
|
NUS
|
Zeng Huaqiang
|
|
13
|
Characterization of Smad3 function in skeletal muscle growth and atrophy
|
NTU
|
Ravi Kambadur
|
|
14
|
Self-Assembly and Ordered Structure of Phospholipid Complexes with Nucleosome and Chromatin
|
NTU
|
Lars Nordenskiöld
|
|
15
|
Roles of RanGTP in the nuclear accumulation of Survivin and its impact on apoptosis
|
NTU
|
Li Hoi Yeung
|
|
16
|
Lipid metabolism in the survival of dopaminergic neurons - relevance to Parkinson's Disease
|
NUS
|
Sashi Kesavapany
|
|
17
|
Is cystathionine b-synthase a viable therapeutic target for the treatment of acute ischemic stroke?
|
NUS
|
Peter Wong Tsun-Hon
|
|
18
|
Molecular characterization of the novel tumor suppressor DLEC1: tissue distribution and cellular localization, mechanism of cell cycle arrest and function as a transcription factor
|
NUS
|
Hooi Shing Chuan
|
|
19
|
The molecular and structural basis of leukocyte b2 integrins signalling
|
NTU
|
Surajit Bhattacharyya
|
|
20
|
Proteome-wide investigation of kinase/substrate interactions using a novel “kinase trapping” probe and its application in drug discovery
|
NUS
|
Yao Shao Qin
|
|
21
|
Surviving neurons in sclerotic CA1 area of the hippocampus: their extra- and intra-hippocampal connections and neurophysiological property in the mouse model of human intractable temporal lobe epilepsy
|
NNI
|
Tang Feng Ru
|
|
22
|
Rab22B/Rab31, a brain-enriched small GTPase in astrocytic membrane traffic and brain pathophysiology
|
NUS
|
Tang Bor Luen
|
|
23
|
Structural and functional characterization of wildtype and three alternatively spliced forms of the Foxp3 protein, the key transcription factor involved in lymphoma
|
NUS
|
Kunchithapadam Swaminathan
|
|
24
|
Role of microRNAs in lipid metabolism
|
NUS
|
Theresa Tan May Chin
|
|
25
|
Analysis of PTEN's function with its interacting protein ZO-2
|
NUS
|
Koichi Okumura
|
|
26
|
Study the Involvement of Reactive Oxygen Species and Rho GTPase in Statin-induced Apoptosis of Breast Cancer Cells
|
NUS
|
Shazib Pervaiz
|
|
27
|
Coronavirus ribonucleocapsid assembly and its replicase enzymes: structure and function
|
NTU
|
Julien Lescar
|
|
28
|
Singapore Alliance for Antimicrobial Peptides
|
SERI
|
Roger Wilmer Beuerman
|
|
29
|
The Immunomodulatory Effects of Probiotics on the Th2 Immune Responses: Role of Gut Dendritic Cells
|
NUS
|
Chua Kaw Yan
|
|
30
|
Optimisation and preclinical studies of prophylactic and therapeutic DNA vaccines for dust mite allergy and allergic asthma
|
NUS
|
Chua Kaw Yan
|
|
31
|
Validation and Use of the Distributed Parameter Tracer Kinetic Model for Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE MRI) of Hepatocellular Carcinoma
|
NCC
|
Thng Choon Hua
|
|
32
|
Gerontology Research Programme: Nutritional, cardiometabolic and vascular factors, ApoE4 gene interactions, and dementia and depression risk
|
NUS
|
Ng Tze Pin
|
|
33
|
Identifying novel genes involved in isoniazid resistance in Mycobacterium tuberculosis using new technology
|
NCC
|
Ann Lee Siew Gek
|
|
34
|
Molecular Evaluation of Gut Microbiota Signatures in Infants with Eczema
|
NUS
|
Lee Bee Wah
|
|
35
|
Systematic study on genetic and epimutational profile of hereditary nonpolyposis colorectal cancer in Singapore
|
SGH
|
Liu Yanqun
|
|
36
|
Development and validation of high-density micro-fluidic real-time PCR platform to enable parallel single-cell molecular genomic analysis
|
NCC
|
Hui Kam Man
|
|
37
|
Identification of human plaque protein signatures predictive for secondary cardiovascular events using quantitative proteomics
|
NTU
|
Newman Sze Siu Kwan
|
|
38
|
Trans-splicing correction of survival motor neuron gene pre-mRNA in patient and mouse model cell lines: A novel therapeutic strategy for Spinal Muscular Atrophy
|
SGH
|
Yee Woon Chee
|
RESULTS
|
S/N
|
Title
|
Host Institution
|
Principal Investigator
|
|
1
|
Interaction of transient axonal glycoprotein 1 (TAX/TAG1) and amyloid precursor protein (APP): an investigation of downstream signaling and functions in adult neural stem cells
|
NUS
|
Gavin Dawe
|
|
2
|
Identification and characterization of cancer stem cells from gastric cancer
|
NUS
|
Chan Shing Leng
|
|
3
|
Tumor tropism of human bone marrow-derived mesenchymal stem cells is mediated by matrix metalloproteinase 1
|
NCC
|
Paula Y P Lam
|
Theme: “In vivo immune-regulation during Infection, Inflammation, Autoimmunity and Cancer
RESULTS
|
S/N
|
Title
|
Host Institution
|
Project Coordinator
|
|
|
1
|
Role of bone-marrow derived cells in tumor-induced lymph node lymphangiogenesis in a mouse model of human melanoma and its significance in human cancer dissemination
|
NUS
|
Angeli Veronique
|
|
|
2
|
Differential regulation of CD14/NFAT and NF-κB pathway in myeloid populations
in human gram-negative sepsis and endotoxin “de-sensitization”
|
NUH/ NUS
|
Philip Lau
|
|
|
3
|
HBV-related hepatocarcinoma: molecular and functional characterization of tumour target and effector immune cells
|
NUH
|
Krishnakumar Madhavan
|
|
|
4
|
Structural, functional and immunological characterization of a Plasmodium multigene family associated with the pathogenesis of cerabral malaria
|
NTU
|
Julien Lescar
|
|
|
5
|
Innate immunity against malaria: Studies on the mechanisms of Plasmodium-phagocyte interactions and their consequences
|
NUS
|
Kevin Tan S W
|
|
|
6
|
The role CD39 in the control of inflammatory immune reactions
|
NUS
|
Mike Kemeny
|
|
|
7
|
Genetically engineered IL-2 deficient dendritic cells: the study of in vivo role of IL-2 produced by dendritic cells
|
NTU
|
Christiane Ruedl
|
|
|
8
|
A Genome-wide association study on atopy and allergic diseases in Singaporean Chinese
|
NUS
|
Wang De Yun
|
|
|
9
|
A Phase I/II Single Centre Study to Determine the Safety and Efficacy of a Combination of Regulatory T cells and Rapamycin for the Treatment of Acute Graft Versus Host Disease
|
SGH, CTM, NCC
|
Goh Yeow Tee
|
|
Theme: Imaging Immune System and Infectious Diseases
RESULTS
|
S/N
|
Title
|
Host Institution
|
Network Director
|
|
1
|
Assessing trafficking and tissue distribution of live and subunit vaccines against Mycobacterium tuberculosis by dynamic, in vivo fluorescence imaging using ultrafine upconversion fluorescent nanoparticles
|
NUS
|
Sylvie Alonso
|
|
2
|
Understanding the mechanism of splenic clearance of malaria infected red blood cells
|
NTU
|
Peter Preiser
|
RESULTS
|
S/N
|
Title
|
Host Institution
|
Principal Investigator
|
|
1
|
Influence of Fetal Growth on Cognition and Brain Development in Children
|
NUS
|
Qiu Anqi
|
|
2
|
Mechanisms of Epigenetic Control of Leptin-STAT3 Axis in the Body Homeostasis
|
NUS
|
Fu Xing Yuan
|