Engineering CELLS,
   Engineering RESPONSES

Metabolomic Analysis

Metabolomics is the global study of small organic compounds with molecular weight of less than 1000 Da. This technology has been useful in analyzing compositions of spent culture media and in characterizing the cell state in various biological systems. Recently, this tool has also been applied for the identification of potential disease biomarkers.

The Metabolomics group has developed expertise in the preparation of samples from cells, culture supernatant, tissues and clinical fluids, as well as the analysis of metabolites using ultra performance liquid chromatography-mass spectrometry (UPLC-MS). We have used this technology to study metabolic behaviour related to cell growth, protein productivity and biomarker discovery. Some of the services that we can provide include:

  • Aqueous metabolite profiling
  • Lipid metabolite profiling
  • Sample preparation by liquid-liquid extraction
  • Statistical data analysis

For enquires regarding Metabolomic Analysis, please email: tan_tuang_kin@bti.a-star.edu.sg