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2013



Substrate-based peptidomimetic inhibitors of the Murray Valley encephalitis virus NS2B/NS3 serine protease: a P1–P4 SAR study
European Journal of Medicinal Chemistry
Melgious Jin Yan Ang, Gerald Han Jie Yong, Anders Poulsen, Siew Wen Then, Zhitao Li, Joma Joy, Jeffrey Hill, Cheng San Brian Chia

Effect of Serine392 Phosphorylation on Structure and Dynamics of PB domain of ARNO protein: A Molecular Simulations study
Biochemistry
Kannan Srinivasaraghavan, Kassoum Nacro, Gerhard Grüber, Chandra S. Verma

Targeting of the MNK-eIF4E axis in blast crisis chronic myeloid leukemia inhibits leukemia stem cell function
Proceedings of the National Academy of Sciences
S. Lim, T. Y. Saw, M. Zhang, M. R. Janes, K. Nacro, J. Hill, A. Q. Lim, C.-T. Chang, D. A. Fruman, D. A. Rizzieri, S. Y. Tan, H. Fan, C. T. H. Chuah, S. T. Ong

Two-step evolution of the hepatitis B drug-resistant mutations in a patient who developed primary entecavir resistance
Liver international : official journal of the International Association for the Study of the Liver. 2013
Lee GH, Inoue M, Toh JK, Chong RH, Aung MO, Koay ES

1H, 13C and 15N chemical shift assignments for the N-terminal PAS domain of the KCNH channel from Zebrafish
Biomolecular NMR Assignments
Young Mee Kim, Qingxin Li, Hui Qi Ng, Ho Sup Yoon, CongBao Kang

NMR Analysis of a Novel Enzymatically Active Unlinked Dengue NS2B-NS3 Protease Complex
Journal of Biological Chemistry
Y. M. Kim, S. Gayen, C. Kang, J. Joy, Q. Huang, A. S. Chen, J. L. K. Wee, M. J. Y. Ang, H. A. Lim, A. W. Hung, R. Li, C. G. Noble, L. T. Lee, A. Yip, Q.-Y. Wang, C. S. B. Chia, J. Hill, P.-Y. Shi, T. H. Keller

Structure of the C-terminal Region of the Frizzled Receptor 1 in Detergent Micelles
Molecules
Shovanlal Gayen, Qingxin Li, Young Kim, CongBao Kang

Drug Design For Flavivirus Proteases: What Are We Missing?
Current Pharmaceutical Design
Anders Poulsen, Congbao Kang, Thomas Keller

Cumulative viral evolutionary changes in chronic hepatitis B virus infection precedes hepatitis B e antigen seroconversion
Gut
Y. Cheng, S. Guindon, A. Rodrigo, L. Y. Wee, M. Inoue, A. J. V. Thompson, S. Locarnini, S. G. Lim

Accelerating the design of biomimetic materials by integrating RNA-seq with proteomics and materials science
Nature Biotechnology
Paul A Guerette, Shawn Hoon, Yiqi Seow, Manfred Raida, Admir Masic, Fong T Wong, Vincent H B Ho, Kiat Whye Kong, Melik C Demirel, Abdon Pena-Francesch, Shahrouz Amini, Gavin Z Tay, Dawei Ding, Ali Miserez

Functional role of the flexible N-terminal extension of FKBP38 in catalysis
Scientific reports
CongBao Kang, Hong Ye, Joel Chia, Bo-Hwa Choi, Sirano Dhe-Paganon, Bernd Simon, Ulrike Sch\u00fctz, Michael Sattler, Ho Sup Yoon

Combination treatment for myeloproliferative neoplasms using JAK and pan-class I PI3K inhibitors
Journal of Cellular and Molecular Medicine
Meng Ling Choong, Christian Pecquet,Vishal Pendharkar, Carmen C. Diaconu, Jacklyn Wei Yan Yong, Shi Jing Tai, Si Fang Wang, Jean-Philippe Defour, Kanda Sangthongpitag, Jean-Luc Villeval, William Vainchenker d, Stefan N. Constantinescu b, May Ann Lee

Lyso-myristoyl phosphatidylcholine micelles sustain the activity of Dengue non-structural (NS) protein 3 protease domain fused with the full-length NS2B
Protein Expression and Purification
Qiwei Huang, Qingxin Li, Joma Joy, Angela Shuyi Chen, David Ruiz-Carrillo, Jeffrey Hill, Julien Lescar, Congbao Kang

Prospective Surveillance and Molecular Characterization of Seasonal Influenza in a University Cohort in Singapore
PLoS ONE
Ramandeep Kaur Virk, Paul Anantharajah Tambyah, Masafumi Inoue, Elizabeth Ai-Sim Lim, Ka-Wei Chan, Catherine Chua, Boon-Huan Tan

Dimerization of Flavivirus NS4B Protein
Journal of Virology
J. Zou, X. Xie, L. T. Lee, R. Chandrasekaran, A. Reynaud, L. Yap, Q.-Y. Wang, H. Dong, C. Kang, Z. Yuan, J. Lescar, P.-Y. Shi

Solution structure of the transmembrane domain of the insulin receptor in micelles
Biochimica et Biophysica Acta (BBA) - Biomembranes
Qingxin Lia, Ying Lei Wong, CongBao Kang

Solution structure of the cyclic-nucleotide binding homology domain of a KCNH channel
Journal of Structural Biology
Qingxin Li, Hui Qi Ng, Ho Sup Yoon, Congbao Kang

Exploring the binding of peptidic West Nile Virus NS2B-NS3 protease inhibitors by NMR
Antiviral Research
CongBao Kang, Shovanlal Gayen, Weiling Wang, Rene Severin, Angela Shuyi Chen, Huichang Annie Lim, Cheng San Brian Chia, Andreas Schüller, Danny Ngoc Phouc Doan, Anders Poulsen, Jeffrey Hill, Subhash G. Vasudevan, Thomas H. Keller