iCORE Microscopy

We enable research in the biomedical sciences by providing:

  • A team of dedicated expert staff to train and support users
  • A wide range of light microscopes and techniques for imaging across the length scales a at high spatiotemporal resolution.
  • Image analysis software on powerful workstations
  • Regular practical training courses in microscopy and image analysis

We house 21 high-end light microscopes and currently have over 250 regular users. We operate either by training users to be independent or as a service facility in which the microscopy is carried out with users by our experts. Once trained, users have access to our online booking system to plan their experiments.

iCORE Microscopy also hosts the A*STAR-EVIDENT Microscopy Platform, where we have access to the latest technology and instrumentation from Evident, as well as enjoying excellent support.

Key Services

  • Slide scanning services (Brightfield, Widefield fluorescence, Cross-linear/Circular Polarization)
  • Staff-assisted Imaging
  • Courses/Workshops – Microscopy Fundamentals/Advanced Microscopy/Image Processing with Image

Key Applications / Techniques

  • Brightfield & Widefield - Nikon Ni-E upright
  • Confocal - Olympus FV3000 Inverted, Olympus FV3000RS Inverted (with resonance scanner), Olympus FV3000RS upright (with resonance scanner), Zeiss LSM700 inverted, Zeiss LSM800 inverted, Zeiss LSM800 upright, Zeiss LSM800 Airyscan
  • Confocal Spinning Disk - Spinning Disk 3D FRAP
  • F-Techniques - Leica Stellaris 8
  • Image Processing Workstation - Computer Tekong and Bukom
  • Live-cell Imaging - Zeiss AxioObserver 7 HCS, Olympus IX-83, Nikon Ti-E Inverted
  • Light sheet - Ultramicroscope II
  • Multi-photon - LaVision II Multiphoton
  • Super-resolution - ONi Nano imager
  • Slide scanning - Zeiss Axio Scan 7 (Brightfield, Widefield Fluorescence, Polarisation)
Leica-Stellaris
Zeiss-Axio-Observer-7-HCS
Nikon-Ti-E-Inverted

Scientific Software

  • Fiji (ImageJ)
  • QuPath
  • CellProfiler
  • Celluose
  • CellSens
  • FluoView
  • NIS-Elements
  • ZEN
  • LAS X
  • Imaris & Imaris Stitcher & Imaris File Converter
  • Huygens Deconvolution

Our People

The iCORE Microscopy Platform is supported by a dedicated team of five with strong expertise in microscopy training and image analysis. The team works closely with researchers to provide hands‑on user training, advanced imaging support, and image analysis guidance, enabling high‑quality, reproducible imaging outcomes across diverse research applications.


Picture6

Team Members: Team lead: Ma Xiaoxiao (Top Right); Asst Manager: Goh Wah Ing (Top Left); Image Analyst: John Lim (Bottom Left); Research Officer: Annisa Ibrahim (Bottom Right); Evident, Products Manager: Lin Shuping (Not in photo)

Contact us to learn more about our platforms, services and how our team can support your research needs.