Microfluidics: A Thousand Captures at a Time

IME researchers have developed a silicon-based device for use in drug discovery. The device has demonstrated simultaneous capture of 12 individual cells - 12x higher throughput than conventional patch clamping. The device could be scaled up to allow 1152 cell-recordings at the same time. With automation, the proposed device has the potential to dramatically shorten drug development cycle for rapid screening of drug candidates.