Immunoinformatics

PI/Head: Bernett LEE, Ph.D.

For more information regarding the SIgN Immunoinfomatics Platform and services, please download a copy of our brochure here.

The Immunoinformatics Platform uses state-of-the-art methods to analyse SIgN data and deliver pipelines and workflows to accelerate research

Overview

The Immunoinformatics platform uses state-of-the-art methods to analyse SIgN data and deliver pipelines and workflows to accelerate research. The bioinformatics team handles not only the "usual" datasets, such as microarray and next-generation sequencing data, but also various heterogeneous datasets, such as those derived by flow cytometry, ELISA and Luminex assays and assesses the cross-correlation between these data (Figure 1).

Technologies and Applications

  • Accelrys Pipeline Pilot 
  • Tibco Spotfire 
  •  MySQL 
  • R
  • Metacore/GeneGo 
  • Ingenuity Pathway Analysis 
  • Oncomine 
  • Transfac 
  • Tuxedo suite for NGS analysis

Our equipment includes: 

  • 31 node, 8 cores/node, 48Gb RAM/node linux cluster 
  • 12 core, 64Gb RAM, 18 Tb RAID5 linux workstation 
  • 6 core, 48Gb RAM, 35 Tb RAID5 Solaris database server and backup storage

bioinformatics platform

Figure 1: Examples of data analysis
Bioinformatics workflow
Figure 2: Data analysis workflow