Tumors Hide by Mimicking Foetal Characteristics to Gain Immune Tolerance

Discovery of how tumours gain immune tolerance more by activating cellular mechanisms involved in foetal development.

Ramanuj DasGupta
Genome Institute of Singapore (GIS)
Florent Ginhoux
Singapore Immunology Network (SIgN)

Onco-fetal Reprogramming of Endothelial Cells Drives Immunosuppressive Macrophages in Hepatocellular Carcinoma more
Cell

rnavelocity
Steady state RNA velocity: Directionality of myeloid cell states predicted by RNA velocity suggest tumour macrophages are derived from reprogrammed monocytes.