Bacteriophage DNA Modifications
A collaborative study with researchers from China and US led to the discovery of the mechanism for synthesis of DNA genomes containing the bases ZGTC, instead of AGTC in regular DNA.
A*STAR’s Singapore Institute of Food and Biotechnology Innovation (SIFBI), ShanghaiTech University and Tianjin University in China, and the University of Illinois at Urbana-Champaign in USA
A Widespread Pathway for Substitution of Adenine by Diaminopurine in Phage Genomes
Science
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Modified Z base forms a triple bond with a T base on the complementary DNA strand.
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