A chronic wound is one that fails to heal in an orderly and timely fashion. Chronic wounds disrupt patients’ lifestyle and present a substantial economic burden to healthcare systems globally. Current diagnosis depends on visual assessment, but identification of non-healing wounds is challenging due to poorly defined macroscopic changes.
Under the Wound Care Innovation programme, we aim to identify wound exudate biomarkers distinguishing hard-to-heal wounds against healing wounds. Using microRNA therapeutics, we also aim to develop novel strategies to accelerate wound closures. We have also identified novel pathways implicated in wound healing which could be targeted for potential therapeutics. Our programme aims to identify solutions to accelerate wound healing, mitigate complications associated with chronic wounds, with improved patient outcomes and in the long run prevent amputations.