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Engineering CELLS,
   Engineering RESPONSES


Advancing Knowledge

New knowledge creation is at the heart of every research institute. BTI conducts cutting edge research in:

  • Immunology
  • Stem Cells
  • Bioprocess Science and Engineering
  • Glycobiology
  • Metabolic Engineering / Synthetic Biology

Enhancing Competency

Pharmaceutical companies are currently providing multi-billion dollar manufacturing output to Singapore's economy. It is Singapore's ambition to add biologics manufacturing as the next growth engine. To support the growth of this sector, young scientific talent is being nurtured at BTI with relevant industrial training programmes as well as scholarships.

Developing Technologies

BTI is developing novel bioprocess technologies, some examples of which are highlighted below:

  • Engineering high producing cell lines
  • Generating glycosylation mutants
  • Preventing apoptosis of cell lines in bioreactors
  • Protein-free chemically defined media
  • Expansion of human embryonic stem cells and differentiated cell types
  • Quantitative and qualitative determination of glycoproteins
  • Comprehensive analysis of media components & intracellular metabolites
  • High sensitivity proteomics to distinguish phenotypic traits for superior protein production
  • Novel bioseparation technologies
  • Application of "-Omics" Technologies to Food and Nutrition R&D
  • Microbiome
  • Instrumentation and Medical Devices