Cell Line Engineering
Directing glycobiotechnology for industrial applications
The Cell Line Engineering group focuses on being at the frontier of Glycobiotechnology and its industrial applications. We engineer novel CHO cells lines, signal peptides, selection markers, and systems to enhance productivity and efficacy of recombinant therapeutics while boosting cell line stability and productivity. Through our work, we are working towards generating significant cost-effective and bioprocessing advantages for biosimilars and biotherapeutics.
- Genome editing of mammalian cell lines
- Glycoengineering of CHO cells
- Attenuated GS as selection markers in CHO cells for enhanced biologics production
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