PUBLICATIONS

SHOW ALL GO

"KDM6B Counteracts EZH2-Mediated Suppression of IGFBP5 to Confer Resistance to PI3K/AKT Inhibitor Treatment in Breast Cancer." Wang W, Lim KG, Feng M, Bao Y, Lee PL, Cai Y, Chen Y, Zhang H, Marzese D, Hoon DSB, Yu Q - Mol Cancer Ther 2018 Sep ; 17(9) : 1973-1983

2018

Abstract

"Hypoxic tumor microenvironment activates GLI2 via HIF-1α and TGF-β2 to promote chemoresistance in colorectal cancer." Tang YA, Chen YF, Bao Y, Mahara S, Yatim SMJM, Oguz G, Lee PL, Feng M, Cai Y, Tan EY, Fong SS, Yang ZH, Lan P, Wu XJ, Yu Q - Proc Natl Acad Sci U S A 2018 06 26 ; 115(26) : E5990-E5999

2018

Abstract

"No association between resistance mutations, empiric antibiotic, and mortality in ceftriaxone-resistant Escherichia coli and Klebsiella pneumoniae bacteremia." Heng ST, Chen SL, Wong JGX, Lye DC, Ng TM - Sci Rep 2018 Aug 24 ; 8(1) : 12785

2018

Abstract

"Long-read whole genome sequencing and comparative analysis of six strains of the human pathogen Orientia tsutsugamushi." Batty EM, Chaemchuen S, Blacksell S, Richards AL, Paris D, Bowden R, Chan C, Lachumanan R, Day N, Donnelly P, Chen S, Salje J - PLoS Negl Trop Dis 2018 06 ; 12(6) : e0006566

2018

Abstract

"Premenopausal women with recurrent urinary tract infections have lower quality of life." Ennis SS, Guo H, Raman L, Tambyah PA, Chen SL, Tiong HY - Int J Urol 2018 Jul ; 25(7) : 684-689

2018

Abstract

"An Outbreak of Streptococcus pyogenes in a Mental Health Facility: Advantage of Well-Timed Whole-Genome Sequencing Over emm Typing." Bergin SM, Periaswamy B, Barkham T, Chua HC, Mok YM, Fung DSS, Su AHC, Lee YL, Chua MLI, Ng PY, Soon WJW, Chu CW, Tan SL, Meehan M, Ang BSP, Leo YS, Holden MTG, De P, Hsu LY, Chen SL, de Sessions PF, Marimuthu K - Infect Control Hosp Epidemiol 2018 Jul ; 39(7) : 852-860

2018

Abstract

"A Sub-population of Group A Streptococcus Elicits a Population-wide Production of Bacteriocins to Establish Dominance in the Host." Hertzog BB, Kaufman Y, Biswas D, Ravins M, Ambalavanan P, Wiener R, Angeli V, Chen SL, Hanski E - obe 2018 Mar 14 ; 23(3) : 312-323.e6

2018

Abstract

"Purification of Intracellular Bacterial Communities during Experimental Urinary Tract Infection Reveals an Abundant and Viable Bacterial Reservoir." Duraiswamy S, Chee JLY, Chen S, Yang E, Lees K, Chen SL - Infect Immun 2018 Apr ; 86(4) :

2018

Abstract

"Draft Genome Sequence of Singapore Klebsiella pneumoniae subsp. pneumoniae Isolate DS32358_14, Which Contains the Carbapenemase Gene blaVIM-1." Koh TH, Abdul Rahman NB, Teo JWP, La MV, Periaswamy B, Chen SL - Genome Announc 2018 Jan 04 ; 6(1) :

2018

Abstract

"Complete Genome Sequence of Photobacterium leiognathi Strain JS01." Soh JYK, Russell CW, Fenlon SN, Chen SL - Genome Announc 2018 Jan 04 ; 6(1) :

2018

Abstract

"Putative Integrative Mobile Elements That Exploit the Xer Recombination Machinery Carrying blaIMI-Type Carbapenemase Genes in Enterobacter cloacae Complex Isolates in Singapore." Koh TH, Rahman NBA, Teo JWP, La MV, Periaswamy B, Chen SL - Antimicrob Agents Chemother 2018 Jan ; 62(1) :

2018

Abstract

"A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer." Wu L, Shi W, Long J, Guo X, Michailidou K, Beesley J, Bolla MK, Shu XO, Lu Y, Cai Q, Al-Ejeh F, Rozali E, Wang Q, Dennis J, Li B, Zeng C, Feng H, Gusev A, Barfield RT, An drulis IL, Anton-Culver H, Arndt V, Aronson KJ, Auer PL, Barrdahl M, Baynes C, Beckmann MW, Benitez J, Bermisheva M, Blomqvist C, Bogdanova NV, Bojesen SE, Brauch H, Brenner H, Brinton L, Broberg P, Brucker SY, Burwinkel B, Caldés T, Canzian F, Carter BD, Castelao JE, Chang-Claude J, Chen X, Cheng TD, Christiansen H, Clarke CL, Collée M, Cornelissen S, Couch FJ, Cox D, Cox A, Cross SS, Cunningham JM, Czene K, Daly MB, Devilee P, Doheny KF, Dörk T, Dos-Santos-Silva I, Dumont M, Dwek M, Eccles DM, Eilber U, Eliassen AH, Engel C, Eriksson M, Fachal L, Fasching PA, Figueroa J, Flesch-Janys D, Fletcher O, Flyger H, Fritschi L, Gabrielson M, Gago-Dominguez M, Gapstur SM, García-Closas M, Gaudet MM, Ghoussaini M, Giles GG, Goldberg MS, Goldgar DE, González-Neira A, Guénel P, Hahnen E, Haiman CA, Håkansson N, Hall P, Hallberg E, Hamann U, Harrington P, Hein A, Hicks B, Hillemanns P, Hollestelle A, Hoover RN, Hopper JL, Huang G, Humphreys K, Hunter DJ, Jakubowska A, Janni W, John EM, Johnson N, Jones K, Jones ME, Jung A, Kaaks R, Kerin MJ, Khusnutdinova E, Kosma VM, Kristensen VN, Lambrechts D, Le Marchand L, Li J, Lindström S, Lissowska J, Lo WY, Loibl S, Lubinski J, Luccarini C, Lux MP, MacInnis RJ, Maishman T, Kostovska IM, Mannermaa A, Manson JE, Margolin S, Mavroudis D, Meijers-Heijboer H, Meindl A, Menon U, Meyer J, Mulligan AM, Neuhausen SL, Nevanlinna H, Neven P, Nielsen SF, Nordestgaard BG, Olopade OI, Olson JE, Olsson H, Peterlongo P, Peto J, Plaseska-Karanfilska D, Prentice R, Presneau N, Pylkäs K, Rack B, Radice P, Rahman N, Rennert G, Rennert HS, Rhenius V, Romero A, Romm J, Rudolph A, Saloustros E, Sandler DP, Sawyer EJ, Schmidt MK, Schmutzler RK, Schneeweiss A, Scott RJ, Scott CG, Seal S, Shah M, Shrubsole MJ, Smeets A, Southey MC, Spinelli JJ, Stone J, Surowy H, Swerdlow AJ, Tamimi RM, Tapper W, Taylor JA, Terry MB, Tessier DC, Thomas A, Thöne K, Tollenaar RAEM, Torres D, Truong T, Untch M, Vachon C, Van Den Berg D, Vincent D, Waisfisz Q, Weinberg CR, Wendt C, Whittemore AS, Wildiers H, Willett WC, Winqvist R, Wolk A, Xia L, Yang XR, Ziogas A, Ziv E, Dunning AM, Pharoah PDP, Simard J, Milne RL, Edwards SL, Kraft P, Easton DF, Chenevix-Trench G, Zheng W - Nat Genet 2018 Jun 18

2018

Abstract

"A comprehensive tool for measuring mammographic density changes over time." Eriksson M, Li J, Leifland K, Czene K, Hall P - Breast Cancer Res Treat 2018 Jun ; 169(2) : 371-379

2018

Abstract

"Inherited factors contribute to an inverse association between preeclampsia and breast cancer." Yang H, He W, Eriksson M, Li J, Holowko N, Chiesa F, Hall P, Czene K - Breast Cancer Res 2018 Jan 23 ; 20(1) : 6

2018

Abstract

"Determinants of breast size in Asian women." Lim LY, Ho PJ, Liu J, Chay WY, Tan MH, Hartman M, Li J - Sci Rep 2018 Jan 19 ; 8(1) : 1201

2018

Abstract

"Population genomics in South East Asia captures unexpectedly high carrier frequency for treatable inherited disorders." Bylstra Y, Kuan JL, Lim WK, Bhalshankar JD, Teo JX, Davila S, Teh BT, Rozen S, Tan EC, Liew WKM, Yeo KK, Tan P, Saw SM, Cheng CY, Cook S, Foo R, Jamuar SS - Genet Med 2018 Jul 02

2018

Abstract

"Pharmacological inhibition of DNA methylation attenuates pressure overload-induced cardiac hypertrophy in rats." Stenzig J, Schneeberger Y, Löser A, Peters BS, Schaefer A, Zhao RR, Ng SL, Höppner G, Geertz B, Hirt MN, Tan W, Wong E, Reichenspurner H, Foo RS, Eschenhagen T - J Mol Cell Cardiol 2018 Jul ; 120 : 53-63

2018

Abstract

"Targeting Chondroitin Sulfate Glycosaminoglycans to Treat Cardiac Fibrosis in Pathological Remodeling." Zhao RR, Ackers-Johnson M, Stenzig J, Chen C, Ding T, Zhou Y, Wang P, Ng SL, Li PY, Teo G, Rudd PM, Fawcett JW, Foo RSY - Circulation 2018 Jun 05 ; 137(23) : 2497-2513

2018

Abstract

"Experience of Asian males communicating cardiac genetic risk within the family." Kam S, Bylstra Y, Forrest L, Macciocca I, Foo R - J Community Genet 2018 Jul ; 9(3) : 293-303

2018

Abstract

"PURA syndrome: clinical delineation and genotype-phenotype study in 32 individuals with review of published literature." Reijnders MRF, Janowski R, Alvi M, Self JE, van Essen TJ, Vreeburg M, Rouhl RPW, Stevens SJC, Stegmann APA, Schieving J, Pfundt R, van Dijk K, Smeets E, Stumpel CTRM, Bok LA, Cobben JM, Engelen M, Mansour S, Whiteford M, Chandler KE, Douzgou S, Cooper NS, Tan EC, Foo R, Lai AHM, Rankin J, Green A, Lönnqvist T, Isohanni P, Williams S, Ruhoy I, Carvalho KS, Dowling JJ, Lev DL, Sterbova K, Lassuthova P, Neupauerová J, Waugh JL, Keros S, Clayton-Smith J, Smithson SF, Brunner HG, van Hoeckel C, Anderson M, Clowes VE, Siu VM, Ddd Study T, Selber P, Leventer RJ, Nellaker C, Niessing D, Hunt D, Baralle D - J Med Genet 2018 Feb ; 55(2) : 104-113

2018

Abstract

"Mutation hotspots at CTCF binding sites coupled to chromosomal instability in gastrointestinal cancers." Guo YA, Chang MM, Huang W, Ooi WF, Xing M, Tan P, Skanderup AJ - Nat Commun 2018 Apr 18 ; 9(1) : 1520

2018

Abstract

"Identification of Tumor Initiating Cells with a Small-Molecule Fluorescent Probe by Using Vimentin as a Biomarker." Lee YA, Kim JJ, Lee J, Lee JHJ, Sahu S, Kwon HY, Park SJ, Jang SY, Lee JS, Wang Z, Tam WL, Lim B, Kang NY, Chang YT - Angew Chem Int Ed Engl 2018 Mar 05 ; 57(11) : 2851-2854

2018

Abstract

"Bystander CD8+ T cells are abundant and phenotypically distinct in human tumour infiltrates." Simoni Y, Becht E, Fehlings M, Loh CY, Koo SL, Teng KWW, Yeong JPS, Nahar R, Zhang T, Kared H, Duan K, Ang N, Poidinger M, Lee YY, Larbi A, Khng AJ, Tan E, Fu C, Mathew R, Teo M, Lim WT, Toh CK, Ong BH, Koh T, Hillmer AM, Takano A, Lim TKH, Tan EH, Zhai W, Tan DSW, Tan IB, Newell EW - Nature 2018 May 16

2018

Abstract

"Development of a new patient-derived xenograft humanised mouse model to study human-specific tumour microenvironment and immunotherapy." Zhao Y, Shuen TWH, Toh TB, Chan XY, Liu M, Tan SY, Fan Y, Yang H, Lyer SG, Bonney GK, Loh E, Chang KTE, Tan TC, Zhai W, Chan JKY, Chow EK, Chee CE, Lee GH, Dan YY, Chow PK, Toh HC, Lim SG, Chen Q - Gut 2018 Mar 30

2018

Abstract

"DNA-mediated dimerization on a compact sequence signature controls enhancer engagement and regulation by FOXA1." Wang X, Srivastava Y, Jankowski A, Malik V, Wei Y, Del Rosario RCH, Cojocaru V, Prabhakar S, Jauch R - Nucleic Acids Res 2018 Apr 14

2018

Abstract

"ConsensusDriver Improves upon Individual Algorithms for Predicting Driver Alterations in Different Cancer Types and Individual Patients." Bertrand D, Dris sler S, Chia BK, Koh JY, Li C, Suphavilai C, Tan IB, Nagarajan N - Cancer Res 2018 Jan 01 ; 78(1) : 290-301

2018

Abstract

"The liver-gut microbiota axis modulates hepatotoxicity of tacrine in the rat." Yip LY, Aw CC, Lee SH, Hong YS, Ku HC, Xu WH, Chan JMX, Cheong EJY, Chng KR, Ng AHQ, Nagarajan N, Mahendran R, Lee YK, Browne ER, Chan ECY - Hepatology 2018 01 ; 67(1) : 282-295

2018

Abstract

"Elucidating the genomic architecture of Asian EGFR-mutant lung adenocarcinoma through multi-region exome sequencing." Nahar R, Zhai W, Zhang T, Takano A, Khng AJ, Lee YY, Liu X, Lim CH, Koh TPT, Aung ZW, Lim TKH, Veer avalli L, Yuan J, Teo ASM, Chan CX, Poh HM, Chua IML, Liew AA, Lau DPX, Kwang XL, Toh CK, Lim WT, Lim B, Tam WL, Tan EH, Hillmer AM, Tan DSW - Nat Commun 2018 Jan 15 ; 9(1) : 216

2018

Abstract

Main Menu