Guillaume Carissimo obtained his PhD in 2014 from Université Pierre et Marie Curie (Sorbonne Universities) and Pasteur Insitute in Paris, where he used functional genomics to study Anopheles and Aedes mosquito antiviral immunity to arboviruses and Plasmodium parasites in vivo. During his PhD, he characterized the contribution of different immune pathways in several mosquito compartments, the opposite contribution of microbiota in vector competence and discovered novel insect specific viruses. He then joined the laboratory of Professor Lisa F.P. Ng at the Singapore Immunology Network, A*STAR, to study the mammalian side of antiviral immunity. He has also been involved in developing tools and novel approaches to better understand host factors interplay with viral replication and immune response both in vitro and in animal models. Guillaume Carissimo participated in the national COVID-19 research efforts alongside ID Labs members and published several research articles on the immune response dysregulation during SARS-CoV-2 infection. Guillaume Carissimo obtained the NMRC-Young Investigator Research Grant in November 2020 to study virus host hijacking using multiOmics strategies, and was appointed Investigator in April 2021 to lead the Host Pathogens Interactions lab within the Infectious Disease Laboratories research institute of A*STAR.

Adjunct Position

  • Adjunct Assistant Professor, National University Singapore Infectious Diseases Translational Research Programme

Research Focus 

The Host Pathogens Interactions Lab is using multiOmics coupled with classical virology and immunology approaches to study pathogen hijacking of cellular pathways and their impact on antimicrobial defence and immunity. Characterization of these mechanisms target by multiple pathogen families will make them attractive targets for host-directed broad-spectrum therapies development.

Lab Members

Postdocs (PhD)Research OfficersPhD/Undergraduate Students
Samuel TONGEstelle GOH
 Ming Xuan LIM