Publications

Wright GD, Ward AM, Bard F, Calvert ME. Pushing the boundaries of high content imaging. Cytometry A. 2017 Feb;91(2):113-114. doi: 10.1002/cyto.a.23063 Link

Fazil MH, Ong ST, Chalasani ML, Low JH, Kizhakeyil A, Mamidi A, Lim CF, Wright GD, Lakshminarayanan R, Kelleher D, Verma NK. GapmeR cellular internalization by macropinocytosis induces sequence-specific gene silencing in human primary T-cells. Sci Rep. 2016 Nov 24;6:37721. doi: 10.1038/srep37721. Link

Eng HY, Wang CI, Xue Y, Lee CY, Zulkifli SB, Chiam PC, Ghadessy FJ, Lane DP. Enhanced antigen detection in immunohistochemical staining using a 'digitized' chimeric antibody. Protein Eng Des Sel. 2016 Jan;29(1):11-21. doi: 10.1093/protein/gzv054. Link

Calvert ME, Ward AM, Wright GD, Bard F. New developments and novel applications in high throughput and high content imaging. Cytometry Part A (2016) 89: 705-707. doi: 10.1002/cyto.a.22921. Link

Xie W, Horn HF, Wright GD. Superresolution Microscopy of the Nuclear Envelope and Associated Proteins. Methods Mol Biol. 2016;1411:83-97. doi: 10.1007/978-1-4939-3530-7_4. Link

Wright GD, Horn HF. Three-dimensional image analysis of the mouse cochlea. Differentiation (2016) S0301-4681(16)30001-9. doi: 10.1016/j.diff.2016.01.002. Link

Itoh H, Arai S, Sudhaharan T, Lee SC, Chang YT, Ishiwata S, Suzuki M and Lane EB. Direct organelle thermometry with fluorescence lifetime imaging microscopy in single myotubes. Chem. Commun. (2016) DOI: 10.1039/C5CC09943A Link

Liu G, Yong MY, Yurieva M, Srinivasan KG, Liu J, Lim JS, Poidinger M, Wright GD, Zolezzi F, Choi H, Pavelka N, Rancati G. Gene essentiality is a quantitative property linked to cellular evolvability. Cell (2015) 163: 1388-1399. Link

Calvi A, Wong AS, Wright G, Wong ES, Han Loo T, Stewart CL, Burke B. SUN4 is essential for nuclear remodeling during mammalian spermiogenesis. Dev Biol. 2015 pii: S0012-1606(15)30200-1. doi: 10.1016/j.ydbio.2015.09.010. Link

Chaumet A, Wright GD, Seet SH, Tham KM, Gounko NV, Bard F. Nuclear envelope-associated endosomes deliver surface proteins to the nucleus. Nature Communications. 2015 Sep 10;6:8218. doi: 10.1038/ncomms9218. Link

Fischer-Zirnsak B, Escande-Beillard N, Ganesh J, Tan YX, Al Bughaili M, Lin AE, l Sahai I, Bahena P, Reichert SL, Loh A, Wright GD, Liu J, Rahikkala ER, Pivnick EK, Choudhri AF, Krüger U, Zemojtel T, van Ravenswaaij-Arts C, Mostafavi R, Stolte-Dijkstra I, Symoens S, Pajunen L, Al-Gazali L, Meierhofer D, Robinson PN, Mundlos S, Villarroel CE, Byers P, Masri A, Robertson SP, Schwarze U, Callewaert B, Reversade B, Kornak U. Recurrent de novo mutations affecting residue p.Arg138 of pyrroline-5-carboxylate synthase cause a novel progeroid form of autosomal dominant cutis laxa. The Americal Journal of Human Genetics. 2015 Aug 27; 97:1-10. doi: 10.1016/j.ajhg.2015.08.001 Link

Chojnowski A, Ong PF, Wong ESM, Lim JSY, Mutalif RA, Navasankari R, Dutta B, Yang H, Liow YY, Sze SK, Boudier T, Wright GD, Colman A, Burke B, Stewart CL, Dreesen O. Progerin reduces LAP2α-telomere association in Hutchinson-Gilford progeria. eLife. 2015 Aug 27; 10.7554/eLife.07759 Link

Li L, Ng DSW, Mah WC, Almeida FF, Rahmat SA, Rao VK, Leow SC, Laudisi F, Peh MT, Goh A, Lim JSY, Wright GD, Mortellaro A, Taneja R, Ginhoux F, Lee C, Moore PK & Lane DP. A unique role for p53 in the regulation of M2 macrophage polarization. Cell Death and Differentiation 2015 Jul;22(7):1081-93. doi:10.1038/cdd.2014.212. PubMed

Wee C, Teo S, Oey NE, Wright GD, VanDongen HMA & VanDongen AMJ. Nuclear Arc interacts with the histone acetyltransferase Tip60 to modify H4K12 acetylation. eNeuro (2014) e0019-14.2014 1–20. doi: 10.1523/ENEURO.0019-14.2014

Chou AM, Sem KP, Wright GD, Thankiah S & Ahmed S. Dynamin1 is a novel target for IRSp53 and works with Mena and Eps8 to regulate filopodial dynamics. The Journal of Biological Chemistry (2014) 289: 24383-24396. doi: 10.1074/jbc.M114.553883 PubMed

Lim J, Lee HK, Yu W, Ahmed S. Light sheet fluorescence microscopy (LSFM): past, present and future. Analyst 2014 Oct 7; 139(19):4758-68. doi:10.1039/c4an00624k PubMed


Horn HF, Kim DI, Wright GD, Wong ESM, Stewart CL, Burke B & Roux KJ. A mammalian KASH domain protein coupling meiotic chromosomes to the cytoskeleton. The Journal of Cell Biology (2013) 202: 1023-1039. doi: 10.1083/jcb.201304004 PubMed

Featured as cover image.

Conference proceedings

Ahmed S, Chou A, Sem KP, Thankiah S, Wright GD, Lim JSY, Hariharan S. Using dSTORM to probe the molecular architecture of filopodia. Proceedings of SPIE (2014) 8950. doi:10.1117/12.2058123

 

ASCB TV - The Institute of Medical Biology (IMB)- Fighting Skin Disease in Singapore 
 

A*STAR Research - October 2014
"Life on the big screen" - A prize-winning microscopy image of a developing mouse sperm cell taken by A*STAR scientists lights up Times Square in New York
 

 

MediaCorp Channel 5 - National Science Challenge - July 2014

Graham Wright featured as a panel judge on the National Science Challenge 2014 - Episode 2 - Quarter Final 1 and the IMU team hosted a visit to IMU by the competitors.

 

YouTube - GE Healthcare 2013 Cell Imaging Competition: Winners Event in New-York

The 2013 GE Healthcare Cell Imaging Competition winners share the inspiration for their research and stories behind their winning images; footage taken from the winners' event in New York where a video of their images was shown in Times Square on April 26th 2014.

 

Straits Times - March 2014

"Beautiful Science"

 

Straits Times - 2012

"High Precision Microscope: Seeing cells in very fine detail"

  The Asian & Oceanian Photochemistry Association - April 2012

A review of IMU's capabilities

 

Straits Times - March 2012

"Five questions for... Dr Graham Wright"

 

Straits Time - May 2011

"Scientists' close encounters of a cellular kind"