Research Fellows

Research Fellow (postdoctoral) position - Computational Bioimage Analysis (CBA)

Date posted: 06 Aug 2018

Date available: immediate

There is one Research Fellow (postdoctoral) position available in the Computational Bioimage Analysis (CBA) Unit of the Institute of Molecular and Cell Biology (IMCB), A*STAR, Singapore. The project is to use image processing and machine learning solutions for the prostate cancer diagnosis and prognosis using digitalized pathology slides. For a research overview of our unit, please refer to http://www.imcb.a-star.edu.sg/php/cba.php

General requirements:

    • Self-motivated scientist/Ph. D graduate to pursue a scientific career. Independent and passionate about biological image processing projects;
    • Good team player. Able to undertake independent research projects under the direction of the PI together with other lab members
    • Hold a Ph.D. in a relevant field of computer vision, image processing or machine vision;
    • Good general knowledge and concept of science and engineering;
    • Excellent scientific/technical writing and communication skills
    • Prior experience in working with image analysis projects (Industrial or academic).

Specific technical requirements:

    • Excellent experience, knowledge, and skills in one or two of the following programming languages, i.e., Matlab, C/C++, Java or Python;
    • Excellent knowledge and skills in digital image processing;
    • Hands-on skills for numerical computational algorithms;
    • Rigid and logical thinking of scientific problems;
    • General understanding of machine learning, pattern recognition, and artificial intelligence is a plus, but not compulsory;
    • Basic knowledge of cell biology or pathology is an advantage;
    • Able to present research achievements at internal/external seminars and conferences

Please email a detailed CV containing a list of publications to Dr. Weimiao YU, 
wmyu@imcb.a-star.edu.sg


We regret that only shortlisted applicants will be notified.

Laboratory of Molecular and Vascular Medicine

Date posted: 25 Jul 2018

Date available: immediate

We are currently recruiting a postdoctoral fellow who will join the Laboratory of Molecular and Vascular Medicine. Our lab focuses on the genetic and metabolic basis of blood vessel dysfunctions underlying neurological and cardiovascular diseases. We aim to advance the understanding of vascular pathology through mechanistic interrogation of clinical biomarkers and development of human induced pluripotent stem cell-based disease models. Highly motivated individuals who are interested to work in an interdisciplinary environment are encouraged to apply. For more information,
please visit: http://www.lkcmedicine.ntu.edu.sg/aboutus/Faculty-and-Staff/Pages/Christine-Cheung.aspx
or
https://www.a-star.edu.sg/imcb/Science/Investigators/Independent-Fellows/Independent-Fellows-Profile/ResearchListID/10

Responsibilities:

  • Initiate and lead projects related to mechanisms of vascular pathology.
  • Involve in experimental planning, data analysis, manuscript preparation and grant applications.
  • Present research findings at seminars and conferences.
  • Contribute to collaborative projects.
  • Guide and train students and junior lab members.
  • Assist in lab management with other lab members.
  • Uphold research integrity and ensure safety compliance.

Skills and qualifications:

  • Applicants should possess a PhD in life sciences, biomedical sciences, biochemistry, bioengineering or equivalent from a well-recognized university.
  • Experience with stem cells, molecular and cell biology and/or gene editing will be considered favorably.
  • Good publication records in peer-reviewed journals.
  • Able to undertake independent research and be an effective team player.
  • Strong analytical, technical and problem solving skills.
  • Committed, able to work flexible hours and within the deadline.
  • Excellent written and oral communication skills.

Application Procedure:
If you are interested to pursue a career with us, please email your 1-page cover letter, CV (including publications) and contact details of two referees to:

Please email a detailed CV containing a list of publications to

Asst Prof Christine Cheung
Email: ccheung@imcb.a-star.edu.sg

Please note that only shortlisted candidates will be notified.

IMCB - Research Fellow (ZQ) | Biopolis | Full-Time

Date posted: 09 May 2018

Date available: immediate

COMPANY PROFILE
The Agency for Science, Technology and Research (A*STAR) is Singapore’s lead government agency for economic-oriented Research and Development (R&D). We advance science and develop innovative technology to further economic growth and improve lives. For more information about A*STAR, please visit: www.a-star.edu.sg 

DIVISION & RI / ENTITY PROFILE
The Institute of Molecular and Cell Biology (IMCB) was launched on 23 January 1985, with its official opening ceremony held on 2 October 1987 at the National University of Singapore (NUS).  It subsequently became an autonomous research institute (RI) of A*STAR, moving to Biopolis in 2004. IMCB’s vision is to be a premier cell and molecular biology institute which addresses the mechanistic basis of human diseases and its mission is to conduct cutting-edge discovery research in disease pathways; to groom early career researchers to be future leaders in research; and to collaborate with medical and industry communities for research impact. IMCB plays an important role training and recruiting scientific talents, and has contributed to the development of other research entities in Singapore. Its success in fostering a biomedical research culture in Singapore has catalysed Singapore’s transformation into an international hub for biomedical research, development and innovation.

Funded primarily by the Biomedical Research Council (BMRC) of A*STAR, IMCB’s discovery research focus is on Cancer Cell Signaling; Epigenetics and diseases; iPS cell and regenerative medicine; and Cell biology and diseases. IMCB’s translational research focus is on Genome-wide RNAi; Humanized mouse models; Proteomics and Protein engineering; and Molecular Histopathology.


JOB DESCRIPTION
(Job Ref: BMSI/IMCB/RF/ZQ/030518)
A Research Fellow position is available at Prof Qi ZENG’s lab.
For more information about the lab, please visit www.a-star.edu.sg/imcb/qz

JOB REQUIREMENTS
• Ph.D or M.D in a related field
• Excellent at Molecular / Cellular / Biochemical Techniques, Protein Works, Animal Models, Histology and Pathology
• Competent in scientific report writing

Interested applicants are welcome to write in with a detailed resume, supporting documents and contact numbers to:
Human Resources Department  recruit@imcb.a-star.edu.sg

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies.
These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified. 

 

Research Fellow: Humanized Mouse Unit (HMU)

Date posted: 30 Apr 2018

Date available: immediate

Two Research Fellow (postdoctoral) positions are immediately available in the Humanized Mouse Unit (HMU) of the Institute of Molecular and Cell Biology, A*STAR, Singapore.

The understanding of many biological processes in humans relies on experimental studies in animal models, particularly rodents. However, many aspects of the human biological system are species specific, such as human specific cell types and immune genes. Our mission is to develop humanized mouse models which closely recapitulate in vivo human biology for the study of human diseases and drug development. This is critical to the understanding and development of therapeutics to many human specific diseases. For a research overview please refer to   http://www.imcb.a-star.edu.sg/php/ittd-hmu.php

Specific requirements:

  • The candidate should be self-driven to pursue a scientific career, motivated, independent and passionate about immunology research
  • Hold a PhD in a relevant field of immunology or virology.
  • Good knowledge and concept of immunology and demonstrated research experience and achievement
  • Good technical writing skills
  • Prior experience in working with mice, flow cytometry, immunofluorescence etc.

Responsibilities:

  • Undertake independent research under the direction of the PI and with other lab members
  • Assist the PI in quality control for experiments, data analysis, manuscript preparation, grant applications and lab management
  • Assist the PI in guiding and training students and junior research staff.
  • Present research achievements at internal and external seminars and conferences

Please email a detailed CV containing a list of publications to
Dr. Qingfeng Chen,
qchen@imcb.a-star.edu.sg.

We regret that only shortlisted applicants will be notified.


Postdoctoral fellow position (Metabolism, cell cycle, and liver diseases)

Date posted: 27 Mar 2018

A postdoctoral position is available in the laboratory of Dr. Philipp Kaldis at the Institute of Molecular and Cell Biology (IMCB), A*STAR. We are using a combination of omics-approaches (RNAseq, ChIPseq, metabolomics, and lipidomics) and mouse genetics to study how metabolism is re-wired during liver disease as a function of cell division. We are looking for a postdoctoral fellow that can drive this project and will be collaborating with multiple research groups.

Singapore is an excellent environment to do research with many research groups close by in Biopolis
 [https://www.a-star.edu.sg/imcb]

Requirements:
• PhD in Cell, Molecular Biology, Biochemistry, or Genetics
• Experience in liver biology, mouse genetics, or metabolism
• Enthusiastic, passionate, and competitive in research
• Able to work in highly collaborative environment

Interested applicants should send a CV, publication list, a brief description of research interests and experience, and three confidential letters of reference to:

Dr. Philipp Kaldis
email: kaldis@imcb.a-star.edu.sg
https://www.a-star.edu.sg/imcb/Science/Scientific-Programmes/Scientific-Programmes-Profile/ResearchListID/3

We regret that only shortlisted applicants will be notified.

Research Fellow (postdoctoral) position

Date posted: 02 Feb 2018

Date available: 1 May 2018

One Research Fellow (postdoctoral) position is available on May 01, 2018 in the Computational Bioimage Analysis (CBA) Unit of Institute of Molecular and Cell Biology (IMCB), A*STAR, Singapore.

Novel imaging analysis methods are making it feasible to extract quantitative information from digital images. There are two closely related topics: Computational Bioimage Analysis and Quantitative Imaging Informatics. The former refers to the automatic analysis of acquired biological images (2D, 3D or 4D) using computational solutions and the extraction of different features; the latter relates to processing the features and extracting quantitative information, which will be essential to understanding the biological/medical phenomena and building traceable classification/prediction models. New knowledge, skills, and approaches are urgently required to develop novel, efficient and reliable computational tools for emerging challenges in biological studies. The general question is how to provide timely and suitable solutions for the images/videos acquired in different scientific and industrial applications. Our CBA Unit is dedicated to the development of new solutions in this field. Currently, we are expanding our team and seeking enthusiastic scientists to join us!

For a research overview of our unit, please refer to https://www.a-star.edu.sg/imcb/Science/Scientific-Services/Scientific-Services-Profile/ResearchListID/131

General requirements:

  • Self-motivated scientist/Ph. D graduate to pursue a scientific career. Independent and passionate about biological image processing projects
  • Good team player. Able to undertake independent research projects under the direction of the PI together with other lab members
  • Hold a Ph.D. in a relevant field of computer vision, image processing or machine vision
  • Good general knowledge and concept of science and engineering
  • Excellent scientific/technical writing skills and communication capability
  • Prior experience in working with image analysis projects (Industrial or academic)

Specific technical requirements:

  • Excellent experience, knowledge, and skills in one or two following programming languages, i.e., Matlab, C/C++, Java or Python
  • Excellent knowledge and skills in digital image processing
  • Hands-on skills for numerical computational algorithms
  • Rigid and logical thinking of scientific problems
  • General understanding of machine learning, pattern recognition, and artificial intelligence is a plus, but not compulsory
  • Basic knowledge of cell biology or pathology is a value-add
  • Present research achievements at internal/external seminars and conferences

Please email a detailed CV containing a list of publications
to Dr. Weimiao YU, wmyu@imcb.a-star.edu.sg

We regret that only shortlisted applicants will be notified.