22 Nov 2018 11:00 AM

Level 3, IMCB Seminar Room 3-46, Proteos, Biopolis

Computational microscopy of order across biological scales

Speaker:Dr. Shalin Mehta



Living systems are characterized by emergent behavior of ordered components. Imaging technologies that reveal dynamic arrangement of organelles in a cell and of cells in a tissue are needed to understand the emergent behavior of living systems. I will present an overview of challenges in imaging dynamic order at the scales of molecular assemblies, cells and tissues. I will present advances in computational label-free microscopy to overcome these challenges.

Biography:

Shalin Mehta received Ph.D. in optics at the National University of Singapore. His Ph.D. research led to better mathematical models and novel approaches for label-free imaging of cellular morphology. He then joined the Marine Biological Laboratory in Woods Hole as Human Frontier Science Program Fellow, where he developed novel imaging and computational methods for detecting molecular order across a range of scales in living systems. He built a microscope that revealed the dynamic flow and orientation of molecular assemblies across the cell. At CZ Biohub, his lab seeks to measure physical properties of biological systems with increasing precision, resolution, and throughput by joint optimization of light-matter interactions and algorithms.

Host: Prof. Wanjin Hong

Seminar is open to public, registration is not required.