Ruan W, Venkatachalam G, Sobota RM, Chen L, Wang LC, Jacobson A, Paramsivam K and Surana U (2019)
Resistance to anti-microtubule drug-induced cell death is determined by regulation of BimEL expression
Oncogene (In Press)
Ruan W, Lim HH and Surana U (2019)
Mapping mitotic death: Functional integration of mitochondria, spindle assembly checkpoint and apoptosis
Frontiers Cell Dev Biol 6:117
Ng CT, Li D, Chen C, Lim HH, Jian Shi J, Surana U, and Gan L (2018)
Electron cryotomography analysis of Dam2C/DASH at the kinetochore-spindle interface in situ
J Cell Biol (In press)
Kannan S, Venkatachalam G, Lim HH, Surana U, Verma C (2018)
Conformational landscape of Epidermal growth factor receptor kinase reveals a mutant specific allosteric pocket
Chemical Science 9:5212-5222
Lin J, Lee JJH, Paramasivam K, Pathak E, Wang Z, Pramono ZAD, Lim B, Wee KB and Surana U (2017)
Nonsense-mediated decay of glycine decarboxylase transcripts as an anticancer therapeutic strategy for non-small cell lung carcinoma
Molecular Therapy N. A. 9:263-273
Venkatachalam G, Surana U and Clément M-V (2017)
Replication stress-induced endogenous DNA damage drives cellular senescence induced by a sub-lethal oxidative stress
Nuclei Acids Research 45:10564-10582
Radiono S *, Pramono ZAD *, Oh GGK, Surana U, Widiyani S, Danarti R (2017)
Identification of Novel Homozygous SLURP1 Mutation in a Javanese Family with Mal de Meleda
International Journal of Dermatology 56:1161-1168
Her Z, Yong KSM, Paramasivam Kathirvel, Tan WWS, Liu M, Chan XY, Tan SY, Man HK, Surana U*, and Chen Q* (2017)
An improved pre-clinical patient-derived liquid xenograft mouse model for acute myeloid leukemia
Journal of Hematology and Oncology 10:162-176
Chen C, Lim HH, Shi J, Tamura S, Maeshima K, Surana U and Gan L (2016)
Budding yeast chromatin is dispersed in a crowded nucleoplasm.
Mol Biol Cell 27:3357-3368
Zhang T, Si-Hoe SL, Hudson DF and Surana U (2016)
Condensin recruitment to chromatin is inhibited by checkpoint kinase Chk2 in response to DNA damage
Cell Cycle (In press)
Liang H, Esposito A, De S, Ber S, Collin P, Surana U, Venkitaraman AR (2014)
Homeostatic control of polo-like kinase-1 engenders non-genetic heterogeneity in G2 checkpoint fidelity and timing
Nature Commun 5:4048.
Yu H, Lim HH et al. (2014)
Chaperoning HMGA2 protein protects stalled replication forks in stem and cancer cells
Cell Rep 6:684-697
Khong J.H., Zhang T., Gunaratne J., Blackstock W. and Surana U. (2012)
‘Reductional anaphase’ in replication defective cells is caused by ubiquitin conjugating enzyme Cdc34-mediated deregulation of the spindle
Cell Cycle 11:2896-2910
Surana U., Liang H. and Lim H.H. (2012)
Staging a recovery from mitotic arrest
Wee K.B., Yio W.K., Surana U., Chiam K.H. (2012)
Transcritpion factor oscillations induce differential gene expressions
Biophysical J 102:2413-2423
Liang H., Lim H.H., Venkitaraman A. and Surana U. (2012)
Cdk1 promotes kinetochore bi-orientation and regulates Cdc20 expression during recovery from spindle checkpoint arrest
EMBO J 31:403-416.
Surana U and Lim H.H. (2011)
Suppressive side of yeast cyclins
Cell Cycle 15;10(18).
Davey G. Wu B., Dong Y., Surana U. and Davey C. (2010)
DNA stretching in the nucleosome facilitates alkylation by an intercalating antitumour Agent
Nucleic Acids Research 38:2081-2088.
Phong M.S., Van-Horn R.D., Li S., Tucker-Kellog G., Surana U. and Ye X.S. (2010)
The p38 MAPK promotes cell survival but is not required for G2 checkpoint arrest of cancer cells in response to DNA damage
Mol. Cell. Biol. 30:3816-3826
Zhang T., Nirantar S., Lim H. H., Sinha I., and Surana U. (2009)
DNA damage checkpoint maintains Cdh1 in active state to inhibit anaphase progression
Developmental Cell , 17:541-551.
Lim H. H., Zhang T. and Surana U (2009)
Regulation of Centrosome Separation in yeast and vertebrates: common threads
Trends in Cell Biology, 19:325-333.
Keng B. N., Surana U, Aguda B. (2009)
Oscillation of the p53-Akt Network: Implication on cell survival and death
PLoS One 4(2):e4407.
Dhar P. K., Thwin C.S., Tun K., Tsumoto Y., Maurer-Stroh, S., Eisenhaber F. and Surana U. (2009)
Synthesizing non-native parts from native genome
J. Biol. Eng. 3(1):2.
Crasta K., Lim H. H., Zhang T., Nirantar S. And Surana U. (2008)
Consorting kinases, end of destruction and birth of a spindle.
Cell Cycle 7:2960-2966.
Crasta K., Lim H. H., T. H. Giddings Jr, M. Winey and Surana U. (2008)
Inactivation of Cdh1 by synergistic action of Cdk1 and Polo kinase is necessary for proper assembly of mitotic spindle
Nature Cell Biology 10: 665-675.
Dong Y., Ng W. K., Surana U., Tan, R. (2008)
Solubilisation and preformulation of poorly water soluble and hydrolysis susceptible N-epoxymethyl-1,8-naphthalimide (ENA) compound
International Journal of Pharmaceutics 356 (1-2):130-136.
Krishnan V., Dirick L., Lim H. H., Lim T. S. J., Si-Hoe S. L., Cheng C. S., Yap K., Ting A., Schwob E. and Surana U. (2007)
A small molecule inhibitor of cell cycle that irreversibly stalls replication forks and activates S phase checkpoint.
Cell Cycle 6 (issue 13)
Crasta K. and Surana U. (2006)
Disjunction of conjoined twins: Cdk1, Cdh1 and separation of centrosomes.
BMC-Cell Division (BioMed Central) 1:12.
Crasta K., Huang P., Morgan G., Winey M. and Surana U. (2006).
Activated Cdk1 promotes centrosome separation by preventing Cdh1-mediated proteolysis of microtubule associated proteins.
EMBO J. 25:2551-2563
Zhang Tao, Lim H. H., Cheng C. S. and Surana U. (2006)
Deficiency of centromere-associated protein Slk19 causes premature nuclear migration and loss of centromeric elasticity.
J. Cell Science 119:519-531.
Padmashree C. G. and Surana U. (2005)
Cdc42-mediated Bud Site Assembly in Yeast is Independent of Its GDP/GTP Exchange Factor Cdc24 but Requires COPI Coatamer Complex.
E. J. Cell Biol. 84:939-49.
Krishnan V. and Surana U. (2005)
Taming the spindle for containing the chromosomes.
Cell Cycle 4(3): e68-e71
Tan L. C. A., Padmashree C. G. R. and Surana U. (2005)
Essential tension and constructive destruction: the spindle checkpoint and its regulatory links with mitotic exit.
Biochem J. 386(1):1-13
Krishnan V., Nirantar S., Crasta K., Cheng A. Y. H. and Surana U. (2004)
DNA-Replication Checkpoint prevents precocious chromosome segregation by regulating spindle dynamics
Mol. Cell 16:687-700
Lim H. H., Yeong F. M. and Surana U. (2003)
Inactivation of mitotic kinase triggers translocation of MEN components to mother-daughter neck in yeast
Mol. Biol Cell 14:4734-4743
Lim H. H. and Surana U. (2003)
Tome-1, wee1 and onset of mitosis: coupled destruction for timely entry
Mol. Cell 11:845-846
Chawla, G., Sapra, A., Surana U., and Vijayraghavan U. (2003)
Dependence of Pre-mRNA introns on PRP17, a non-essential slicing factor: implication for efficient progression through cell cycle transition
Nucleic Acid Res. 31:2333-2343
Yeong F. M., Lim H. H. and Surana U. (2002)
MEN, destruction and segregation: Mechanistic link between mitotic exit and
Cytokinesis in budding yeast
Yeong F. M., Lim, H. H., Wang, Y. and Surana U. (2001)
Early expressed Clb proteins allow accumulation of mitotic cyclin by inactivating proteolytic machinery during S phase
Mol. Cell. Biol., 21:5071-5081.
Padmashree C. G. and Surana U. (2001)
Cdc28-Clb kinase negatively regulates bud-site assembly in the budding yeast
J. Cell Sci. 114:207-218.
Balasubramanian, M. K., McCollum, D. and Surana, U. (2000)
Tying the Knot: Linking cytokinesis to the nuclear division
J. Cell Sci. 113:1503-1513.
Yeong F. M., Lim H. H., Padmeshree, C. G. and Surana U. (2000)
Exit from mitosis in budding yeast: biphasic inactivation of mitotic kinase and the role of Cdc20.
Mol. Cell 5:501-511.
Goh, P-Y., Lim H. H. and Surana, U. (2000)
Cdc20 proteolysis in G1 requires a destruction box but, unlike Clb2, is not acutely dependent on the activity of Anaphase-Promoting Complex.
Eur. J. Biochem. 267:434-449.
Goh, P-Y. and Surana, U. (1999)
Cdc4, a protein required for the initiation of S phase, plays an essential role during G2/M transition in Saccharomyces cerevisiae.
Mol. Cell. Biol. 19:5512-5522.
Loy, C. J., Lydall, D. and Surana, U. (1999)
NDD1, a high dosage suppressor of cdc28-1N, is required for the expression of a subset of late S phase-specific genes in Saccharomyces cerevisiae.
Mol. Cell. Biol. 19:3312-3327.
Lim, H. H., Goh, P-Y. and Surana, U. (1998)
Cdc20 is essential for the APC-mediated proteolysis of both Pds1 and Clb2 during M
phase in budding yeast.
Curr. Biol. 8:231-234.
Dick, T., Surana, U. and Chia, W. (1996).
Molecular and genetic characterization of SLC1, a putative
Saccharomyces cerevisiae homolog of the metazoan cytoplasmic dynein light
Mol. Gen. Genet. 251:38-43.
Lim, H. H. and Surana, U. (1996).
Cdc20, β-transducin homolog, links RAD9-mediated G2/M checkpoint
control to mitosis in Saccharomyces cerevisiae.
Mol. Gen. Genet. 253:138-148.
Christensen, H. E. M., Ramachandran, S., Tan, C-T., Surana, U., Dong, C-H. and Chua, N-H. (1996).
Arabidopsis profilins are functionally similar to yeast profilins: identification of a
vascular bundle-specific profilin and a pollen specific profilin.
The Plant Journal. 10(2):269-279.
Lim, H. H., Goh, P-Y. and Surana, U. (1996).
Spindle pole body separation in S. cerevisiae requires dephospho-
rylation of Tyr19 residue of Cdc28.
Mol. Cell. Biol. 16:6385-6397.
Lim, H. H., Loy, C. J., Zaman S. and Surana, U. (1996).
Dephosphorylation of Threonine169 of Cdc28 is not required for the
exit from mitosis but may be necessary for Start in Saccharomyces
Mol. Cell. Biol. 16:4573-4583.
Surana, U., Amon, A., Dowzer, C., Mcgrew, J., Byers, B. and Nasmyth,
Destruction of the Cdc28/Clb mitotic kinase is not required for
the metaphase to anaphase transition in budding yeast.
EMBO J. 12:1969-1978.
Fitch, I., Dahmann, C., Surana, U., Amon, A., Nasmyth, K., Goetsch, L.,
Byers, B. and Futcher, B. (1992).
Characterisation of four B-type cyclin genes of the budding yeast Saccharomyces cerevisiae.
Mol. Biol. Cell 3:805-818.
Amon, A., Surana, U., Muroff, I. and Nasmyth, K. (1992)
Regulation of p34cdc28 tyrosine phosphorylation is not required for
the entry into mitosis in S. cerevisiae.
Nasmyth, K., Dirick, L., Surana, U., Amon, A. and Cvrckova, F. (1991).
Some facts and thoughts on cell cycle regulation in yeast.
Cold Spring Harbor Symp. Quant. Biol. 56:9-20.
Moll, T., Tebb, G., Surana, U., Robitsch, H. and Nasmyth K. (1991).
The role of phosphorylation and the CDC28 protein kinase in cell
cycle-regulated nuclear import of the S. cerevisiae transcription
Surana, U., Robitsch, H., Price, C., Schuster, T., Fitch I., Futcher, A.
B. and Nasmyth, K. (1991)
The role of CDC28 and cyclins during mitosis in the budding yeast
Thwaites, J. J. and Surana U. (1990)
Mechanical properties of Bacillus subtilis cell wall: effects of removing residual culture medium.
J. Bacteriol. 173:197-203.
Thwaites, J. J., Surana, U. and Jones A. M. (1990).
Mechanical properties of Bacillus subtilis cell wall: Effects of ions and lysozyme
J. Bacteriol. 173:204-210.
Surana, U., Wolfe, A. J. and Mendelson, N. H. (1988)
Regulation of Bacillus subtilis macrofiber twist development by alanine.
J. Bacteriol. 170:2328-2335.
Monod, M., Misaghi, I. G., Mendelson, N. H. and Surana, U. (1986)
Induction of frenching like symptoms in tobacco Macrophomina Phaseolin and its metabolites.
Physiol. Mol. Plant Pathol. 29:19-25.
Mendelson, N. H., Thwaites, J. J., Farve, D., Surana, U., Briehl, M. M., and A. Wolfe. (1985)
Factors contributing to helical shape determination in Bacillus subtilis macrofibers.
Ann. Inst. Pasteur Microbiol. 136A:99-103.