Personal Details

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Dr. SU Xiaodi

Senior Scientist III/Research Councillor, Soft Materials


Soft Materials (SOF) Department

(+65) 6416 8921

2 Fusionopolis Way. Innovis, #08-03, Singapore 138634

Research Details

• Advanced analytical techniques and nanobiosensors for medical diagnosis, food safety, environmental monitoring, agriculture and aquaculture.

Synthesize, functionalization, and processing of metal nanoparticles
Nanomaterial based sensor and assay design 
Studying biomolecular interactions using surface sensitive analytical techniques, e.g. SPR, SPR imager, QCM, DPI, and fluorescent spectroscopy etc.

• Wearable sensors for wound monitoring

• Microbial sensors for industrial water and F&B

Feb 1998 - Current      Research Fellow, Research Scientist, and Senior Scientist, IMRE
1997 - 1998                 Research Associate, Department of Chemistry, National University of Singapore
1996-1997                   Postdoc Fellow, Applied Chemistry Department, Tianjin University, China
  • Ph. D. in Chemistry, Nankai University, China, 1995
  • M. Sc. in Chemistry, Nankai University, China, 1992
  • B. Sc. in Chemistry, Tianjin Normal University, China, 1986
Best Poster Award in the MRS-S Trilateral Conference, Singapore (2010)

Best Poster Award in A-STAR Chemical Symposium, Singapore (2009)

Outstanding University Researcher Award, "Piezoelectric Biosensors for Medial and Veterinary Diagnosis", National University of Singapore (1999)

Second Award of Best Postgraduate Student, Nankai University, China (1992)
  • Adjunct Associate Professor, Dept. Chemistry, National University of Singapore  
  • Adjunct Professor,  School of Engineering and Science , University of the Sunshine Coast, Australia
  • Symposium Chair, ICMAT 2019. Symposium Y: Colloidal Nanoparticle-Based Probes and Sensors (Jointly organized with MRS Japan)
  • Technical program committee, 11th Asian Conference on Chemical Sensors (ACCS 2015).
  • Co-chair ICMAT 2015. Symposium DD. Biohybrid NanoMaterials - Design and Applications 
  • Organization Committee of the 15th Asian Chemical Congress, Singapore, Aug 19-23, 2013.
  • Member of National Institute of Singapore (SNIC)

1.       Roger M Pallares, Xiaodi Su,* Nguyen TK Thanh,* tunable plasmonic colorimetric assay with inverse sensitivity for extracellular DNA quantification. Chem Commn 2018, 54, 11260-11263 

2.       Roger M Pallares, Laura Sutarlie, Xiaodi Su,* Nguyen TK Thanh, Fluorescence sensing of protein-DNA interactions using conjugated polyelectrolytes and graphene oxide, Sensors and Actuators B 2018, 271, 97-103.

3.       Sutarlie L., Ow S. Y., Su X. D.*, Nanomaterials-based Biosensors for Detection of Microorganisms and Microbial Toxins, Biotechnology Journal 2017, 12, 1500459. doi: 10.1002/biot.201500459.

4.       New S.Y.,* Lee S.T. Su, X. D. *, DNA-Templated Silver Nanocluster: Structural Correlation and Fluorescence Modulation, Nanoscale  2016, 8, 17729-17746.

5.       Pallares, R. M., Bosman M., Thanh, N. T. K., and Su X. D. * Plasmonic multi-logic gate platform based on sequence-specific binding of estrogen receptors and gold nanorods, Nanoscale 2016,  8, 19973-19977 (Front Cover)

6.       Pallares, R. M., Wang Y. S., Lim S. H., Thanh, N. T. K., and Su X. D. * Growth of anisotropic gold nanoparticles in photoresponsive fluid for UV exposure sensing and erythema prediction, Nanomedicine 2016,  11, 2845-2860.

7.       Seow, N.; Tan, Y. N.*; Yung, L.;* Su, X. D., DNA-Directed Assembly of Nanogold Dimers: A Unique Dynamic Light Scattering Sensing Probe for Transcription Factor Detection, Scientific Report 2015, 5, 18293.

8.       Pallares, R. M., Su X. D. * and Thanh, N. T. K.*, The Hofmeister Salt Effects on the Fine-Tuning of Gold Nanorod Dimensions and Plasmonic Properties. J Mater Chem C 2015, 4, 53-61 (Front Cover).

9.       Pallares, R. M., Kong, S. L., Tan, H. R., Thanh, N.T.K., Lu, Y., and Su, X. D.,* A plasmonic nanosensor with inverse sensitivity for circulating cell-free DNA quantification. Chem Comm 2015, 51, 14524-14527.

10.    Li, N., Lu, Y., Su, X. D.*, Nanomaterial-based Biosensors using Dual Transducing Elements for Solution Phase Detection, The Analyst 2015, 140, 2916-2943. DOI: 10.1039/C4AN02376E  (Invited Review)




1.     Methods for rapid detection of deletion mutation in circulating tumour DNA, SG patent (pending patent number)

2.     A Total Bacterial Count Method using Metallic Nanostains (pending filing details)

3.     3D anisotropic metal NPs based Flexible SERS sensors, SG Application No.: 10201801989P.

4.     Non-enzymatic colorimetric paper strips for detection of ethanol vapor content, SG10201705506S. IMR/P/10126/00/SG

5.     Nanomaterials-based Bacteria Sensors, SG 10201702528R

6.     Rapid antibody assay using gold nanoparticle, SG10201500466S. PCT/SG2016/050025; US Patent Application No. 15/545,674

7.     Paper-based oxygen-time indicator. SG10201406334R; PCT/SG2015/050374; Oxidant-dependent time indicator 11201702732U

8.     A Plasmonic-Fluorescent Ruler for Site Specific Detection of Protein Binding on Composite DNA, SG10201407072Q.

9.     Protein-based metal nanoclusters for drug discovery. SG 201306645-1

10.  Two-way Free Radical and Antioxidant sensors using Redox-Responsive Fluorescent Metal Nanoclusters. SG 201304947-3

11.  A conjugated polymer-metal nanoparticle hybrid sensor. SG IMR/P/07769/00/SG; 201303638-9. US 14/275,526

12.  A method to detect small molecular drug-protein interactions. SG10201402360U

13.  Enzymatic metal nanoparticles sensor for detecting DNA binders. SG 201306257-5 and US13/968,930; US-2014-0134609-A 1; 10201706751U

14.  Detecting protein-DNA binding using segmented DNA functionalized metal nanoparticles. US 13/377,819, 2012; PCT /SG2010/000196, 2010

15.  Methods for detecting DNA-binding proteins, US Patent No. US 8,709,722. Granted 188068

16.  A method to fabricate gold nanohole array for plasmonic sensing. Singapore Patent Application No. 201105455-8

17.  Method of Forming a Polymer Substrate with Variable Refractive Index Sensitivity US 2013/0295325 A1US Patent Application No. 13/559,533

18.  Method for measuring protein-DNA interactions, PCT/SG2010/000196. US Patent Application No. 13/377,819  

19.  Method for detection of nucleic acid, PCT/SG2010/00004.

20.  Method for detecting surface plasmon resonance. PCT/SG2007/000404. US 8,300,226. Granted

21.  Surface Plasmon Resonance and quartz crystal microbalance sensor, Granted. Application No. 200701937-5.  

22.  Device and Method for Detection of Mutations and Polymorphisms in DNA, Application No. 60/504,434 USA. Granted.

23.  Piezoelectric immunosensor, SG 81232. Granted

24.  A novel immunodiagnostic test method for veterinary disease, PCT application PCT/SG99/0098. Granted.

Last updated on : 08 Apr 2019 08:41 AM