Personal Details

This page is maintained by .

Dr. SU Xiaodi

Senior Scientist III /Head, Nanomaterials


IMRE staff with Adjunct Appointment in University/Industry, Nanomaterials (NMA) Department

(+65) 6416 8921

2 Fusionopolis Way. Innovis, #08-03, Singapore 138634

Research Details

Advanced analytical techniques for medical diagnosis, food safety and environmental monitoring 
Nanomaterials based Process analytical technology (PAT) for pharmbio 
Non-invasive  POC Nanosensors 

Synthesize, functionalization, and processing of metal nanoparticles
Nanomaterial based sensor and assay design 
Studying biomolecular interactions using surface sensitive analytical techniques, e.g. SPR, SPR imager, QCM, DPI, and fluorescent spectroscopy etc.

Nanoparticles-based optical sensors for circulating tumour DNA (ctDNA)
POC sensors for tear diagnosis 
Microbal sensors for industrial water 

Feb 1998 - Current      Research Fellow, Research Scientist, and Senior Scientist, IMRE
March 2017-current     Adjunct Professor,  School of Engineering and Science , University of the Sunshine Coast, Australia
Dec 2012 - Current      Adjunct Associate Professor, Dept. Chemistry, National University of Singapore  
1997 - 1998                 Research Associate, Department of Chemistry, National University of Singapore
1996-1997                   Postdoc Fellow, Applied Chemistry Department, Tianjin University, China
  • Ph. D. in Chemistry, Nankai University, China, 1995
  • M. Sc. in Chemistry, Nankai University, China, 1992
  • B. Sc. in Chemistry, Tianjin Normal University, China, 1986
Best Poster Award in the MRS-S Trilateral Conference, Singapore (2010)

Best Poster Award in A-STAR Chemical Symposium, Singapore (2009)

Outstanding University Researcher Award, "Piezoelectric Biosensors for Medial and Veterinary Diagnosis", National University of Singapore (1999)

Second Award of Best Postgraduate Student, Nankai University, China (1992)
Technical program committee, 11th Asian Conference on Chemical Sensors (ACCS 2015).

Co-chair ICMAT 2015. Symposium DD. Biohybrid NanoMaterials - Design and Applications

Organization Committee of the 15th Asian Chemical Congress, Singapore, Aug 19-23, 2013. Symposium Chairs

Member of American Chemical Society, 2012-date

Member of National Institute of Singapore (SNIC), 2010-date
1. Sutarlie L., Ow S. Y., Su X. D.*, Nanomaterials-based Biosensors for Detection of Microorganisms and Microbial Toxins, Biotechnology Journal 2017, 12, 1500459. 

2. New S.Y.,* Lee S.T. Su X. D.*, DNA-Templated Silver Nanocluster: Structural Correlation and Fluorescence Modulation, Nanoscale 2016, 8, 17729-17746.

3. Pallares, R. M., Bosman M., Thanh, N. T. K., and Su X. D. * Plasmonic multi-logic gate platform based on sequence-specific binding of estrogen receptors and gold nanorods, Nanoscale 2016,  8, 19973-19977 (Front Cover)

4. Pallares, R. M., Wang Y. S., Lim S. H., Thanh, N. T. K., and Su X. D. * Growth of anisotropic gold nanoparticles in photoresponsive fluid for UV exposure sensing and erythema prediction, Nanomedicine 2016,  11, 2845-2860.

5. Seow, N.; Tan, Y. N.*; Yung, L.;* Su, X. D., DNA-Directed Assembly of Nanogold Dimers: A Unique Dynamic Light Scattering Sensing Probe for Transcription Factor Detection, Scientific Report 2015, 5, 18293.

6. Pallares, R. M., Su X. D. * and Thanh, N. T. K.*, The Hofmeister Salt Effects on the Fine-Tuning of Gold Nanorod Dimensions and Plasmonic Properties. J Mater Chem C 2015, 4, 53-61 (Front Cover). 

7. Pallares, R. M., Kong, S. L., Tan, H. R., Thanh, N.T.K., Lu, Y., and Su, X. D.,* A plasmonic nanosensor with inverse sensitivity for circulating cell-free DNA quantification. Chem Comm 2015, 51, 14524-14527. 

8. Li, N., Lu, Y., Su, X. D.*, Nanomaterial-based Biosensors using Dual Transducing Elements for Solution Phase Detection, The Analyst 2015, 140, 2916-2943. DOI: 10.1039/C4AN02376E  (Invited Review)

9. Yu, Y., Xie J.P., Su, X. D.*, Tan Y. N.*, Protein-Based Fluorescent Metal Nanoclusters for Small Molecular Drug Screening, Chem. Comm. 2014, 50, 13805-13808. 

10. New, S. Y., Khin Moh Moh Aung, Lim, M., Tan, S. K., Lu, Y., Cheung, E., Su, X. D.* Fast Screening of Ligand-Protein Interactions based on Ligand-Induced Protein Stabilization of Gold Nanoparticles,  Anal. Chem. 2014, 86, 2361-70. 

11. Song H. Y., Su, X. D.,* End-on Covalent Antibody Immobilization on Dual Polarization Interferometry Sensor Chip for Enhanced Immuno-sensing. Plasmonics 2014, 9, 851-858. 

12. Lukman, S., Aung, K. M. M., Lim, M., Hong, S., Tan, S. K., Cheung, E., Su, X.D.,* Hybrid Assembly of DNA-Coated Gold Nanoparticles with Water Soluble Conjugated Polymers for Studying Protein-DNA Interaction and Ligand Inhibition, by, RSC Adv. 2014,  4, 8883. 

13.Lukman, S., Aung, K.M.M., Liu, J., Liu, B.,Su, X. D.,*Hybrid Sensor Using Gold Nanoparticles and Conjugated Polyelectrolytes for Studying Sequence Rule in Protein–DNA interactions, ACS Appl Mater. Inter, 2014, 5, 12725–12734.

14. Lukman, S., Sutarlie, L.; Li, N., Su X.D.*, A Nanoplasmonic-Fluorescent Ruler for Detection of Site-Specific Protein Binding to Composite DNA of Multiple Sites, Particle & Particle Systems Characterization 2014, 31, 1281-1290. 

15. Song H. Y., Zhou X., Hobley J., Su X. D.* Comparative Study of Random and Oriented Antibody Immobilization as Measured by Dual Polarization Interferometry and Surface Plasmon Resonance Spectroscopy, Langmuir 2012, 28, 997-1004.

16. Su, X. D.,* Liu, X. G, The Plasmonic Ruler Goes 3D! ChemPhysChem 2011, 12, 2707-2708. Invited Highlight 

17. Tan, Y. N., Lee, K. H., Su, X. D.* Study of Single-Stranded DNA Binding Protein–Nucleic Acids Interactions using Unmodified Gold Nanoparticles and Its Application for Detection of Single Nucleotide Polymorphisms. Anal. Chem. 2011, 83, 4251–4257.

18. Chen, K. H., Hobley, J., Foo, Y. L. Su, X. D.*, Wide-field Single Metal Nanoparticle Spectroscopy for High Throughput Localized Surface Plasmon Resonance Sensing, Lab-on-a-Chip 2011, 11, 1895-1901. 

19. Tan, Y. N.; Su, X. D;* Zhu, Y.; Lee, J. Y. “Sensing of Transcription Factor through Controlled-Assembly of Metal Nanoparticles Modified with Segmented DNA Elements.” ACS Nano 2010, 4, 5101–5110. 

20. Tan, Y.N., Su, X. D.,* Liu, E., Thomsen, J. S., A Gold-Nanoparticle-Based Assay for Instantaneous Detection of Transcription Factor-DNA Interactions. Anal. Chem. 2010, 82, 2759-2766. 

21. Su, X. D.,* and Kanjanawarut, R., Control of metal nanoparticles aggregation and dispersion using PNA and PNA-DNA complexes, and its use for colorimetric DNA detection. ACS Nano 2009, 3, 2751–2759. 

22. Kanjanawarut, R. and Su, X. D.,* Colorimetric detection of DNA using unmodified metallic nanoparticles and peptide nucleic acid probes. Anal. Chem. 2009, 81, 6122-6129. 

23. Chen, H.B., Su, X. D., Neoh, K.G., Choe, W.S.,* Engineering LacI for Self-Assembly of Inorganic Nanoparticles on DNA Scaffold through the Understanding of LacI Binding to Solid Surfaces. Adv. Functional Materials 2009, 19, 1186-1192. 

24. Zong, Y.,* Xu, F., Su, X. D., Knoll W., Quartz crystal microbalance with integrated surface plasmon grating coupler Anal. Chem. 2008, 80, 5246-5250. 

25. Chen, H. B.; Su, X. D.,* Neoh, K.G.; Choe, W.S., Probing the interaction between peptides and metal oxides using point mutants of a TiO2-binding peptide, Langmuir 2008, 24, 6852-6857. 

26. Peh, W. Y. X., Reimhult, E., Teh, H. F. and Su, X. D.,* Understanding ligand binding effects on conformation of Estrogen Receptor -DNA complex: A combinational QCM-D and SPR study. Biophysical Journal 2007, 92, 4415-4427. 

27. Su, X. D.,* Wu, Y.-J., Knoll, W., Comparison of surface plasmon resonance spectroscopy and quartz crystal microbalance techniques for the study of DNA assembly and hybridization. Biosensors & Bioelectronics 2005, 21, 719-726. 

28. Liu, Z. L.,* Ling, X. Y., Su, X. D., Lee, J.Y., Gan, L.M.,  Preparation and characterization of Pt/C and Pt-Ru/C electrocatalysts for direct ethanol fuel cells. J. Power Sources 2005, 149: 1-7. 

29. Su, X. D.,* Wu, Y. J., Robelek, R., Knoll, W., A surface plasmon resonance spectroscopy and quartz crystal microbalance study of streptavidin film structure effects on biotinylated DNA assembly and target DNA hybridization. Langmuir 2005, 21, 348-353. 

30.Su, X. D.,* Li, S. F. Y., and O’Shea, S. J., Gold nanoparticle and silver enhancement reaction amplified microgravimetric biosensor. Chem. Commun. 2001, 8, 755-756. 




Sutarlie, L.; Su, X. D.; Yu, Y.; Tan, Y. Nee, Ow, D.; Yang, Y. S.; Ng, S. K.; “Rapid antibody assay using gold nanoparticle”, Singapore patent 10201500466S

Sutarlie, L.; Kwok, S. W.; Su, X. D. “Paper-based oxygen-time indicator”. Singapore patent 10201406334R

Su, X. D.; Lukman, S.; Sutarlie, L., “A Plasmonic-Fluorescent Ruler for Site Specific Detection of Protein Binding on Composite DNA”, Singapore Paten 10201407072Q

Su, X. D.; Lukman, S.; New, S. Y.; Cheung, E. “A conjugated polymer-metal nanoparticle hybrid sensor”. Singapore patent 201303638-9. US Patent 14/275,526

New, S. Y.; Su, X. D.; Cheung, E. “A method to detect small molecular drug-protein interactions”. Singapore Patent 10201402360U

Tan Y. N.; Su, X. D. “Detecting protein-DNA binding using segmented DNA functionalized metal nanoparticles”. US Patent Application No. 13/377,819, 2012; PCT/SG2010/000196, 2010 (Granted)

Shah, K. W., Su, X. D. Chua, S. J.; Low, H. Y., “A method to fabricate gold nanohole array for plasmonic sensing”. Singapore Patent 201105455-8;

Tan, Y. N.; Su, X. D. “Method for measuring protein-DNA interactions”, PCT/SG2010/000196. US Patent 13/377,819 Licensed. Granted Feb2012.

Su, X. D.; Kanjanawarut, R., “Method for detection of nucleic acid”, PCT/SG2010/000047. Licensed Feb2012.

Last updated on : 07 Dec 2017 05:05 PM