I obtained Ph.D. degree from Dep. of Physiology and Biophysics, school of medicine, Inha university, South Korea. During my postdoctroal training, I studied on synaptic plasticity at Pohang University of Science and Technology (POSTECH), South Korea (2005-2009) and on vesicle exocytosis at Max Planck Institut-Experimental Medizine (MPI-EM), Germany (2009-2012). I studied about physiological functions and ultrastructure in ribbon synapse of sensory organ (inner ear) at Synaptic Nanophysiology, Max Planck Institut-Biochemie (MPI-BPC) and Institute for Auditory Neuroscience (InnerEar Lab), University of Göttingen in Germany (2012-2016). I joined the JCO VIP project as a group leader of Neuromodulation and Neurocircuitriy (NMNC) group, Singapore Bioimaging Consortium (SBIC), A*STAR, and as an Adjunct Assistant Prof. at Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore (NUS) in 2016.
Research interests of my group lie in identifying the neuromodulators and neuronal circuitries associated with metabolic syndromes, diabetes and obesity, as well as the underlying mechanisms of diabetes related hearing loss in auditory systems.
1. High frequency neural spiking and auditory signaling by ultrafast red-shifted optogenetics, Mager T, Lopez de la Morena D, Senn V, Schlotte J, D Errico A, Feldbauer K, Wrobel C, Jung S, Bodensiek K, Rankovic V, Browne L, Huet A, Jüttner J, Wood PG, Letzkus JJ, Moser T, Bamberg E. Nat Commun. (2018), 9(1):1750
2. The synaptic ribbon is critical for sound encoding at high rates and with temporal precision., P. Jean, D. Lopez de la Morena, S. Michanski, L.M. Jaime Tobón, R.Chakrabarti, M.M.Picher, J. Neef, S.Y. Jung, M. Gültas, S. Maxeiner, A. Neef, C. Wichmann, N. Strenzke, C. Grabner and T. Moser. eLife. (2018), E29275
3. Hair cells use active zones with different voltage dependence of Ca2+ influx to decompose sounds into complementary neural codes., Ohn TL, Rutherford MA#, Jing Z#, Jung S#, Duque-Afonso CJ, Hoch G, Picher MM, Scharinger A, Strenzke N, Moser T. Proc Natl Acad Sci U S A. (2016), 113 (32): E4716-25, (#Equal contribution)
4. Ca2+-binding protein 2 inhibits Ca2+ channel inactivation in mouse inner hair cells. Maria M. Picher, Anna Gehrt, Sandra Meese, Aleksandra Ivanovic, Friederike Predoehl, Sangyong Jung, Isabelle Schrauwen, Alberto Giulio Dragonetti, Roberto Colombo, Guy van Camp, Nicola Strenzke and Tobias Moser. Proc Natl Acad Sci U S A. (2017), 114 (9): E1717-E1726
5. Disruption of adaptor protein 2µ (AP-2µ) in cochlear hair cells impairs vesicle reloading of synaptic release sites and hearing. Sangyong Jung#, Tanja Maritzen#, Carolin Wichmann#, Zhizi Jing, Andreas Neef, Natalia H. Revelo, Hanan Al-Moyed, Sandra Meese, Sonja M. Wojcik, Iliana Panou, Haydar Bulut, Peter Schu, Ralf Ficner, Ellen Reisinger, Silvio O. Rizzoli, Jakob Neef, Nicola Strenzke, Volker Haucke and Tobias Moser. EMBO J. (2015), 34 (21): 2686-702., (#Equal contribution)
6. Actin Filament Turnover Drives Leading Edge Growth during Myelin Sheath Formation in the Central Nervous System., Nawaz S, Sánchez P, Schmitt S, Snaidero N, Mitkovski M, Velte C, Brückner BR, Alexopoulos I, Czopka T, Jung SY, Rhee JS, Janshoff A, Witke W, Schaap IA, Lyons DA, Simons M. Dev. Cell, (2015), 34 (2): 139-51.
7. Rab3-interacting molecules 2α and 2β promote the abundance of voltage-gated CaV1.3 Ca2+ channels at hair cell active zones., S. Jung#, T. Oshima-Takago#, R. Chakrabarti, M.M. Picher, A.B. Wong, Z. Jing, A.-M. Oprisoreanu, F. Göttfert, S. Michanksi, F. Predoehl, K. Michel, Tina Pangršič-Vilfan, S. M. Hell, S. Schoch, N. Strenzke, C. Wichmann and T. Moser. Proc Natl Acad Sci U S A. (2015), 112(24): E3141-9. (#Equal contribution)