Spectroelectrochemistry of biosensors

Electrochemical-based biosensors have been gaining tractions for healthcare and lifestyle management in modern society. However, the underlined mechanisms of an electrochemical biosensor are often complex to comprehend. Besides electron transfers, the electrode surface may also undergo color changes or generate highly active intermediates which can give off light signals via a radiative pathway. These optical signals provide immense information and valuable insights into the complex chemical process. Spectroelectrochemistry (SEC) is an instrumental technique that combines in-situ and simultaneous spectroscopic and electrochemical measurements during a chemical process. This project will use spectroelectrochemistry to study the complex chemical process and guide the better design of electrochemical biosensors.