Identifying Molecular Determinants of Infertility in men (MODIFY)


What is infertility in men?
Male infertility is greatly underestimated and global data estimates that male infertility accounts for around 20 to 30 percent of infertility cases. A true reflection of the statistics in Singapore where infertility is observed in 15 percent of couples trying for a baby, it's been found that 20 percent of this infertility is attributed to male infertility. Treatment options for female infertility is wide-ranging according to the specific problem. On the other hand, it is now becoming apparent that male infertility is poorly understood. Diagnosis and treatment of male infertility is limited as compared to their female counterparts.


What is SICS doing to help?
We intend to unravel the molecular mechanisms of infertility, hoping to contribute to the development of better diagnostics and treatment options. Our study will help raise awareness of preconception behaviour and its impact on fertility.

How can I help?
You can be part of this mission if you are:

  • A male
  • Aged 21 to 50 years old
  • Able to read or understand English

What will I be doing?
If you decide to be a part of MODIFY, you will be required to come down for one study visit at the Human Development Research Centre. The visit will include informed consent and an eligibility check, followed by study procedures such as anthropometric measurement and completing a lifestyle questionnaire. You will be provided with a collection kit to collect a semen sample in the comfort of your home. A courier service will then be arranged to pick up the semen sample.

Reimbursement will be given for your time. There are no additional costs associated with participating in this study.

To find out more, call (+65) 8854 6302 or email us at