17 A*STAR researchers are recognised as the world's most influential scientific minds in 2022. Find out more about their work and what drives them to push the frontiers of scientific excellence! A*STAR’s Highly Cited Researchers of 2022
Halsey L.G., Careau V., Pontzer H., Ainslie P.N., Andersen L.F., Anderson L.J., Arab L., Baddou I., Bedu-Addo K., Blaak E.E., Blanc S., Bonomi A.G., Bouten C.V.C., Bovet P., Buchowski M.S., Butte N.F., Camps S.G.J.A., Close G.L., Cooper J.A., Das S.K., Cooper R., Dugas L.R., Ekelund U., Entringer S., Forrester T., Fudge B.W., Goris A.H., Gurven M., Hambly C., Hamdouchi A.E., Hoos M.B., Hu S., Joonas N., Joosen A.M., Katzmarzyk P., Kempen K.P., Kimura M., Kraus W.E., Kushner R.F., Lambert E.V., Leonard W.R., Lessan N., Martin C.K., Medin A.C., Meijer E.P., Morehen J.C., Morton J.P., Neuhouser M.L., Nicklas T.A., Ojiambo R.M., Pietiläinen K.H., Pitsiladis Y.P., Plange-Rhule J., Plasqui G., Prentice R.L., Rabinovich R.A., Racette S.B., Raichlen D.A., Ravussin E., Reynolds R.M., Roberts S.B., Schuit A.J., Sjödin A.M., Stice E., Urlacher S.S., Valenti G., Van Etten L.M., Van Mil E.A., Wilson G., Wood B.M., Yanovski J., Yoshida T., Zhang X., Murphy-Alford A.J., Loechl C.U., Luke A.H., Rood J., Sagayama H., Schoeller D.A., Westerterp K.R., Wong W.W., Yamada Y., Speakman J.R. (2022) Variability in energy expenditure is much greater in males than females Journal of Human Evolution. 10.1016/j.jhevol.2022.103229
Janani R., Tan V.W.K., Goh A.T., Choy M.J.Y., Lim A.J., Teo P.S., Stieger M., Forde C.G. (2022) Independent and combined impact of texture manipulation on oral processing behaviours among faster and slower eaters Food and Function. 10.1039/d2fo00485b
Yong, Z., Ram, MS., Persson, K., Subramanian, GS., Wernersson, L., Pan, J. (2022) The Effect of Deposition Conditions on Heterointerface-Driven Band Alignment and Resistive Switching Properties Advanced Electronic Materials. 10.1002/aelm.202200220
Chi H., Wang M., Li J., Tian H., Chong Y.T., Lim S.H., Wang Y., Wang F. (2022) Polyhedral Oligomeric Silsesquioxane as a Polarity Mediator and Reinforced Nanofiller for Fabricating Robust and Hierarchical Porous Film for Cell Bioengineering ACS Applied Polymer Materials. 10.1021/acsapm.2c00775
Chiang, JH., Hua, XY., Yu, AHM., Peh, EWY., See, E., Henry, CJ. (2022) A Review on Buckwheat and Its Hypoglycemic Bioactive Components in Food Systems Food Reviews International. https://doi.org/10.1080/87559129.2022.2103706.
Yong, Y.N., Henry, C.J., Haldar, S. (2022) Is There a Utility of Chrono-Specific Diets in Improving Cardiometabolic Health? Molecular Nutrition and Food Research. 10.1002/mnfr.202200043
Tay, W., Quek, R., Kaur, B., Lim, J., Henry, CJ (2022) Use of Facial Morphology to Determine Nutritional Status in Older Adults: Opportunities and Challenges JMIR Public Health and Surveillance. 10.2196/33478
Tay, J., Goh, M., Ching, WHJ., Arumugam, P. (2022) Floating Sphere Assay: A rapid qualitative method for microvolume analysis of gelation PLOS One. 10.1371/journal.pone.0266309
Villanova, FA., Lin, AH. (2022) Modification of Pea Starch Digestibility through the Complexation with Gallic Acid via High-Pressure Homogenization Polymers. 10.3390/polym14132623
Sugiyama R., Suarez A.F.L., Morishita Y., Nguyen T.Q.N., Tooh Y.W., Roslan M.N.H.B., Lo Choy J., Su Q., Goh W.Y., Gunawan G.A., Wong F.T., Morinaka B.I. (2022) The Biosynthetic Landscape of Triceptides Reveals Radical SAM Enzymes That Catalyze Cyclophane Formation on Tyr- and His-Containing Motifs Journal of the American Chemical Society. 10.1021/jacs.2c00521
Goh, JHC., Liang, C., Wong, JH., Lewis, J., Goh, M., Kong, KW., Yang, LK., Mohammad, A., Yoganathan, K., Hoon, S., Arumugam, P. (2022) Diethyl phthalate (DEP) perturbs nitrogen metabolism in Saccharomyces cerevisiae Scientific Reports. 10.1038/s41598-022-14284-w
Leow Y., Sequerah V., Tan Y.C., Yu Y., Peterson E.C., Jiang C., Zhang Z., Yang L., Loh X.J., Kai D. (2022) A tough, biodegradable and water-resistant plastic alternative from coconut husk Composites Part B: Engineering. 10.1016/j.compositesb.2022.110031
Gakuubi, MM., Ching, KC., Madhaiyan, M., Wibowo, M., Liang, ZX., Yoganathan, K., Ng, SB. (2022) Enhancing the Discovery of Bioactive Secondary Metabolites from Fungal Endophytes using Chemical Elicitation and Variation of Fermentation Media Frontiers In Microbiology. 10.3389/fmicb.2022.898976
Balaji, B., Hua, L., Won, J.C., Wook, M.C. (2022) Potential use of microbial engineering in single-cell protein production Current Opinion in Biotechnology. 10.1016/j.copbio.2022.102740
Nguyen M.N., Krutz N.L., Limviphuvadh V., Lopata A.L., Gerberick G.F., Maurer-Stroh S. (2022) AllerCatPro 2.0: a web server for predicting protein allergenicity potential Nucleic Acids Research. 10.1093/nar/gkac446
Melvin L.K.S., A.Rengaraj, K.Narasimhan, Sanjay K. Verma, J.Yaligar, Giang L. T. T, Sun L.J, H.J Goh, P. Govindharajulu, S.A. Sadananthan, N.Michael, W.Meng, X.Gallart-Palau, L.Sun, N.Karnani, N.S.K.Sze, S.S.Velan (2022) Activated brown adipose tissue releases exosomes containing mitochondrial methylene tetrahydrofolate dehydrogenase (NADP dependent) 1-like protein (MTHFD1L) Bioscience Reports. 10.1042/BSR20212543
Y.X. Duan, Y.F. Wei, M.N. Xing, J.Y.Liu, L. Jiang, Q. Lu. , X.M. Liu, Y.H.Liu, L.A.Ang, R.Z. Liao , Z.G. Yuchi, H.M. Zhao, Y. Zhang (2022) Anaerobic Hydroxyproline Degradation Involving C-N Cleavage by a Glycyl Radical Enzyme Journal of the American Chemical Society. 10.1021/jacs.2c01673
L.L.Tan, E.Heng, N.Zulkarnain, W.C. Hsiao, F.T. Wong, M.M. Zhang (2022) CRISPR/Cas-Mediated Genome Editing of Streptomyces Methods in Molecular Biology. 10.1007/978-1-0716-2233-9_14
Tan R., Chew S., Cleanthous X., Anastasiou K., Brooker P.G., Pham T., Smith B.P.C. (2022) Correction to: Assessment of artificial and natural sweeteners present in packaged non-alcoholic beverages (NABs) sold on the Singapore market (BMC Public Health, (2021), 21, 1, (1866), 10.1186/s12889-021-11924-0) BMC Public Health. 10.1186/s12889-021-12342-y
Smith, D., Helmy, M., Lindley, N., Selvarajoo, K (2022) The transformation of our food system using cellular agriculture: What lies ahead and who will lead it? Trends in Food Science & Technology. 10.1016/j.tifs.2022.04.015
Haldar, S., Ponnalagu, S., Osman, F., Tay, SL., Wong, LH., Jiang, YR., Leow, MKS., Henry, CJ. (2022) Increased consumption of unsaturated fatty acids improves body composition in a hypercholesterolemic Chinese population Frontiers in Nutrition. 10.3389/fnut.2022.869351
Konan, D.,Koffi, E., Ndao, A., Peterson, EC., Rodrigue, D., Adjalle, K. (2022) An Overview of Extrusion as a Pretreatment Method of Lignocellulosic Biomass Energies. 10.3390/en15093002
Tee, SY., Tan, XY., Wang, X., Lee, JJ., Khin, YW., Ni, XP., Teo, SL., Seng, HL., Tanaka, Y., Han, MY. (2022) Aqueous Synthesis, Doping, and Processing of n-Type Ag2Se for High Thermoelectric Performance at Near-Room-Temperature ACS Publications. 10.1021/acs.inorgchem.2c00060
Liu, Y., Wei, Y., Teh, T.M., Liu, D., Zhou, Y., Zhao, S., Ang, E.L., Zhao, H., Zhang, Y. (2022) Identification and Characterization of the Biosynthetic Pathway of the Sulfonolipid Capnine Biochemistry. 10.1021/acs.biochem.2c00102
Zhang, C., Ottenheim, C., Weingarten, M., Ji, LH. (2022) Microbial utilization of next-generation feedstocks for the biomanufacturing of value-added chemicals and food ingredients Frontiers in Bioengineering and Biotechnology. 10.3389/fbioe.2022.874612
"Cheng, HY., Chan, JCY., Yap, GC., Huang, C., Kioh, DYQ., Tham, EH., Loo, EXL., Shek, LPC., Karnani, N., Goh, A., Van Bever, HPS., Teoh, OH., Chan, YH., Lay, C., Knol, J., Yap, F., Tan, KH., Chong, Y., Godfrey, KM., Chan, ECY., Lee, BW., Ta, LDH. (2022) Evaluation of Stool Short Chain Fatty Acids Profiles in the First Year of Life With Childhood Atopy-Related Outcomes Frontiers in Allergy. 10.3389/falgy.2022.873168"
Szenker-Ravi, E., Ott, T., Khatoo, M., de Bellaing, A.M., Goh, W.X., Chong, Y.L., Beckers, A., Kannesan, D., Louvel, G., Anujan, P., Ravi, V., Bonnard, C., Moutton, S., Schoen, P., Fradin, M., Colin, E., Megarbane, A., Daou, L., Chehab, G., Di Filippo, S., Rooryck, C., Deleuze, J.-F., Boland, A., Arribard, N., Eker, R., Tohari, S., Ng, A.Y.-J., Rio, M., Lim, C.T., Eisenhaber, B., Eisenhaber, F., Venkatesh, B., Amiel, J., Crollius, H.R., Gordon, C.T., Gossler, A., Roy, S., Attie-Bitach, T., Blum, M., Bouvagnet, P., Reversade, B. (2022) Publisher Correction: Discovery of a genetic module essential for assigning left–right asymmetry in humans and ancestral vertebrates (Nature Genetics, (2022), 54, 1, (62-72), 10.1038/s41588-021-00970-4) Nature Genetics. 10.1038/s41588-022-01053-8
Thakkar, Y., Joshi, K., Hickey, C., Wahler, J., Wall, B., Etter, S., Smith, B., Griem, P., Tate, M., Jones, F., Oudraogo, G., Pfuhler, S., Choi, C., Williams, G., Guan, N., Greim, H., Eisenbrand, G., Dekant, W., Api, AM. (2022) The BlueScreen HC Assay to Predict the Genotoxic Potential of Fragrance Materials Mutagenesis. 10.1093/mutage/geac004
Lee, HW., Bi, X., Henry, CJ. (2022) Carotenoids, tocopherols and phylloquinone content of 26 green leafy vegetables commonly consumed in Southeast Asia Food Chemistry. 10.1016/j.foodchem.2022.132729
Teo, PS., Lim, A., Goh, AT., Janani, R., Choy, M., McCrickerd, K., Forde, CG. (2022) Texture-based differences in eating rate influence energy intake for minimally processed and ultra-processed meals American Journal of Clinical Nutrition. 10.1093/ajcn/nqac068
Sun, L., Goh, H.J., Verma, S., Govindharajulu, P., Sadananthan, S.A., Michael, N., Henry, C.J., Goh, J.P.-N., Velan, S.S., Leow, M.K.-S. (2022) Brown adipose tissues mediate the metabolism of branched chain amino acids during the transitioning from hyperthyroidism to euthyroidism (TRIBUTE) Scientific Reports. 10.1038/s41598-022-07701-7
Delodder, F., Ritz, A., Foltzer, F., Lamonthe, L., d'Urzo, C., Ludivine, FN., Mauger, J., Morlet, J., Piccardi, N., Philippe, L., Caijo, F., Schmitt, J., Mottaz, SC. (2022) A Decentralized Study Setup Enables to Quantify the Effect of Polymerization and Linkage of α-Glucans on Post-Prandial Glucose Response Nutrients. 10.3390/nu14051123
Chiang, JH., Yeo, MTY., Ong, DSM., Henry, CJ. (2022) Comparison of the molecular properties and volatile compounds of Maillard reaction products derived from animal- and cereal-based protein hydrolysates Food Chemistry. 10.1016/j.foodchem.2022.132609
Jing, J.L., Ning, T.C.Y., Natali, F., Eisenhaber, F., Alfatah, M. (2022) Iron Supplementation Delays Aging and Extends Cellular Lifespan through Potentiation of Mitochondrial Function Cells. 10.3390/cells11050862
Lim, HK., Hughes, C-O., Lim, JSM., Li, JJ., Rakshit, M., Yeo, C., Chng, KR., Li, A., Chan, JSH., Ng, KW., Leavesley, DI., Smith, B. (2022) Development of reconstructed intestinal micronucleus cytome (RICyt) assay in 3D human gut model for genotoxicity assessment of orally ingested substances Archives of Toxicology. 10.1007/s00204-022-03228-y
Dong, Z., Jin, L., Rezaei, SD., Wang, H., Chen, Y., Tjiptoharsono, F., Ho, J., Gorelik, S., Ng, RJH., Ruan, Q., Qiu, C., Yang, JKW. (2022) Schrödinger’s red pixel by quasi-bound-states-in-the-continuum Science Advances. 10.1007/s00204-022-03228-y
Toh, WKD., Akila, SRV., Henry, CJ. (2022) Unknown impacts of plant-based meat alternatives on long-term health Nature Food. 10.1038/s43016-022-00463-5
Trushina, DB., Borodina, TN., Belyakov, S., Antipina, MN. (2022) Calcium carbonate vaterite particles for drug delivery: Advances and challenges Materials Today Advances. 10.1016/j.mtadv.2022.100214
Hua, XY., Chiang, JH., Henry, CJ (2022) Application of plant proteins as alternative emulsifiers in double emulsions: using kappa-carrageenan for complex coacervation and microencapsulation of riboflavin International Journal of Food Science and Technology 2022. 10.1111/ijfs.15599
Chew, EGY., Lim, TC., Leong, MF., Liu, X., Sia, YY., Leong, ST., Yan-Jiang, BC., Stoecklin, C., Borhan, R., Heilmann-Heimbach, S., Nothen, MM., Viasnoff, V., Shyh-Chang, N., Wan, ACA., Philpott, MP., Hillmer, AM. (2022) Observations that suggest a contribution of altered dermal papilla mitochondrial function to androgenetic alopecia Experimental Dermatology. 10.1111/exd.14536
Camps, SG., Koh, HR., Henry, CJ. (2022) Posture economy: the importance of metabolic state on metabolic phenotype assessment and the energy cost of sitting and standing. A whole body calorimetry trial European Journal of Clinical Nutrition. 10.1038/s41430-022-01077-7
Jing, L., Zhang, H., Tan, YL., Zhao, H., Ang, EL. (2022) Directed Evolution of Replication-Competent Double-Stranded DNA Bacteriophage toward New Host Specificity ACS Synthetic Biology. 10.1021/acssynbio.1c00319.
Tee, SY., Khin, YW., Goh, SS., Teng, CP., Tang, YTK., Regulacio, MD., Li, Z., Ye, E. (2022) Chapter 1: Introduction to Photothermal Nanomaterials Photothermal Nanomaterials. 10.1039/9781839165177-00001
Tang, YTK ., Zhi, XHJ., Khin, YW., Tee, SY., Li, Z., Ye, E. (2022) Chapter 3: Branched Metallic Nanocrystals: Synthesis, Properties, and Photothermal Applications Photothermal Nanomaterials. 10.1039/9781839165177-00081
Dong, Z., Mahfoud, Z., Paniagua-Domínguez, R., Wang, H., Fernández-Domínguez, A.I., Gorelik, S., Ha, S.T., Tjiptoharsono, F., Kuznetsov, A.I., Bosman, M., Yang, J.K.W. (2022) Nanoscale mapping of optically inaccessible bound-states-in-the-continuum Light: Science and Applications. 10.1038/s41377-021-00707-2
Stonehouse, W., Klingner, B., Tso, R., Teo, PS., Netsanet, ST., Forde, CG. (2022) Bioequivalence of long-chain omega-3 polyunsaturated fatty acids from foods enriched with a novel vegetable-based omega-3 delivery system compared to gel capsules: a randomized controlled cross-over acute trial European Journal of Nutrition. 10.1007/s00394-021-02795-7
Xu, X., Chew, K.A., Wong, Z.X., Phua, A.K.S., Chong, E.J.Y., Teo, C.K.L., Sathe, N., Chooi, Y.C., Chia, W.P.F., Henry, C.J., Chew, E., Wang, M., Maier, A.B., Kandiah, N., Chen, C.L.-H. (2022) The SINgapore GERiatric Intervention Study to Reduce Cognitive Decline and Physical Frailty (SINGER): Study Design and Protocol Journal of Prevention of Alzheimer's Disease. 10.1002/trc2.12141
Dwijayanti, A., Zhang, C., Poh, CL., Lautier, T. (2022) Toward Multiplexed Optogenetic Circuits Frontiers in Bioengineering and Biotechnology. 10.3389/fbioe.2021.804563