In partnership with Worley Parsons and University of Leeds Medical Technologies this half-day seminar brings together domain experts to share the latest technologies on biomaterial for biomedical devices, simulation tools for developing medtech devices and latest advances on joint replacement implants. Dr Cheryl Liu, Senior Life Sciences Technical Specialist at SIMULIA (the Dassault Systèmes brand for Realistic Simulation solutions), will present an overview of simulation for medical devices and trends in realistic human simulation. Three renowned speakers from University of Leeds will deliver their talks via video conference (webinar) with topics on design & biomechanics, orthopedics and performance & failure of joint replacements prostheses.
12.30pm Registration, Lunch & Networking
1.30pm Introduction to SIMTech MedTech Initiative – Mr. John Lim (SIMTech-PE COI)
1.45pm Overview of Simulation for Medical Devices – Dr Cheryl Liu (Simulia)
This presentation will look at the use of simulation across the medical device industry
by exploring the process of development of a variety of medical devices and
consumables, in Orthopedics, Cardiovascular Devices, Drug Delivery and Medical
2.45pm Trends in Realistic Human Simulation – Dr Cheryl Liu
This presentation will look at some of the progress that has been made recently and the
exciting potential of exploiting simulation to include the behaviour of human beings on
the use of the medical devices.
3.30pm Tea-Break and Networking
4.00pm Key Design Biomechanics of Orthopaedic Joint Replacement Prostheses – Dr Sophie
Williams, University of Leeds [webinar]
4.20pm Simulation Orthopaedic Joint Replacement Prostheses – Dr Mazen Al-Hajjar, University
of Leeds [webinar]
4.40pm Role of Wear Debris on the Performance and Failure of Orthopaedic Joint Replacement
Prostheses – Dr Joanne Tipper, University of Leeds [webinar]
About the Speakers
Dr Cheryl Liu is the Senior Life Sciences Technical Specialist at SIMULIA (the Dassault Systèmes brand for Realistic Simulation solutions). She started her career at SIMULIA in 2006 after receiving her PhD degree in Orthopedic Biomechanics from University of Notre Dame. At SIMULIA she has been focusing on advancing the applications & technologies of simulation, including Abaqus and Isight for design & evaluation of various medical devices. These include orthopedic & cardiovascular implants, drug delivery devices, vision & hearing care products and medical instruments. She works closely with the regulatory bodies and industry associations including FDA and ASME on computational modeling verification and validation for medical device evaluation. She is also actively working with SIMULIA R&D on product development to meet the current and future simulation opportunities in the life sciences industry.
Dr Sophie Williams completed a BEng (hons) at the University in Liverpool in Clinical Engineering and Materials Science. She completed her PhD at the University of Leeds (Institute of Medical and Biological Engineering) in 2002. This assessed the use surface coatings in metal-on-metal hip replacements as a mechanism to reduce wear and wear products, and was under the supervision of Professor John Fisher.
Following her PhD, Dr Williams was the “DePuy Technology Partnership Research Fellow”, managing the interface of research at the University of Leeds and DePuy International. Her work predominantly involved the tribology of hip replacement bearing surfaces.
In 2006, Dr Williams was awarded a prestigious five-year fellowship by the Royal Academy of Engineering (UK) to research the biotribology of cartilage. In 2007, work on developing the novel ceramic-on-metal bearing combination was recognised by the Hip Society (USA) Otto Aufranc award. Additionally, Dr Williams was a BORS-Orthopaedic Research Society inaugural travelling fellow and spent a month in 2007 visiting centres of excellence across the USA. She has been a Senior Lecturer since 2011 and is leading research into the tribology of the natural hip joint.
Dr Williams has published over 60 papers in peer reviewed journals and presented over 140 national and international conference papers. Her current research interests include the tribology of joint replacements and natural cartilage.
Dr Mazen Al-Hajjar is a research fellow working on hip joint replacement devices. His research focuses on the tribology and laboratory simulation of hip replacement bearings. Dr Al-Hajjar completed his undergraduate degree (BEng, 1st class honours) in 2008 in Medical Engineering at Queen Mary University of London with a focus on tissue engineering and joint replacement design. During his undergraduate studies, he gained industrial experience by completing a yearlong placement in the research and development department at a leading orthopaedic company, DePuy Synthes Joint Reconstruction. The work during the placement involved working on the development of hip and knee joint replacements.
He recently completed his PhD at the institute of Medical and Biological Engineering at the University of Leeds in 2012 under the supervision of Dr Louise Jennings, Dr Sophie Williams, Dr Joanne Tipper and Professor John Fisher, focusing on the wear of hard-on-hard bearings (metal-on-metal and ceramic-on-ceramic) under adverse simulator conditions. His research was funded by Orthopaedic research UK.
He has also worked on several other projects, delivering research projects to the institute industrial partners; DePuy Synthesis Joint Reconstruction and Mathys Orthopädie GmbH.
Dr Al-Hajjar has extensive research experience in joint replacement bearings tribology and simulation and has published several peer reviewed journal articles and presented his research at national and international conferences. His current research includes the development of advanced simulation methodologies for testing and developing safer and reliable hip replacement bearings.
Dr Joanne Tipper completed a PhD in skin microbiology at the University of Leeds before moving into the multidisciplinary research field of medical engineering. Over the last 15 years she has been responsible for developing methodologies for isolating wear particles from total joint replacements from both periprosthetic tissues and simulator lubricants. With over 70 peer reviewed publications on the isolation of UHMWPE, metal and ceramic particles and the biological responses to wear debris her work has contributed to the understanding of implant failure. Career highlights include the award of an EPSRC Advanced Fellowship to study patient specific responses to wear particles and invitations to participate in the writing of the ASTM and ISO standards on wear particle isolation. Current projects to isolate, characterise and determine the cellular responses to wear particles from new and novel materials including antioxidant polyethylenes, PEEK and carbon nanotube polyethylene composites are ongoing, along with the investigation of spinal cord cellular responses to wear products from spinal implants and instrumentation. Joanne is now a programme director of two doctoral training centres in Tissue Engineering and Medical and Biological Engineering, which currently comprise over 80 PhD students.
Who Should Attend
This seminar is designed for a multidisciplinary audience of Medical Practitioner, Surgeons, Cinicians, Managers, Department Heads, Directors, MedTech Technicians, Senior Specialists from Hospital and Medical Service Providers; product design & development; quality management, quality by design, manufacturing, process development, process engineering, R&D.
Registration for this seminar is free of charge. Seats are available on first-come, first-served basis. All are welcome. Please register online.
For more details, please contact Mr John Lim Kee Yong, Lead, MedTech Initiative, SIMTech, Senior Consultant, PE COI, Tel: 6793 8248, Email: kylim@SIMTech.a-star.edu.sg