Researcher Portfolio

Deepak Choudhury (Dr)
Scientist II
65903102
Bio-Manufacturing
Introduction:

Deepak is currently a Biomedical Research Scientist as well as Industry Development Manager at Singapore Institute of Manufacturing Technology (SIMTech A*STAR). He received his PhD from NUS and IBN A*STAR. He is driving the tissue manufacturing track under the Bio-Manufacturing Programme (BMP) at SIMTech where he is developing innovative manufacturing processes/platforms. Over the years, Deepak has dealt with mammalian cells, animal tissues, small animal models like drosophila and zebrafish. He has been involved in numerous interdisciplinary projects and is skilful in tissue engineering, bioprinting, biomaterials, 3D prototyping, microfabrication, microfluidics, cellular assays etc. Deepak has mentored 3 PhD students and supervised >20 interns/FYPs. He has received 3 competitive grants and has 3 patent applications and >15 publications to his credit. His first patent has been officially granted and licensed. He also has strong organization skills and has directly managed many scientific as well as cultural events at SIMTech, featuring as an entertaining and funny emcee in many of them.

 

Research Interest:

  • Bioprinting, Bioinks development, In situ/In vivo bioprinting modules, Tissue engineering, Cultured Meat, Biomaterials processing, 3D Printing/prototyping, Microfluidics, Microfabrication, Organ-On-Chips, Animal-On-Chips (Drosophila and Zebrafish assay systems)

BioNotes:

PhD, National University of Singapore and Institute of Bioengineering and Nanotechnology A* Star, Singapore, 2012  

R & D Assistant, Jawaharlal Nehru Centre for Advanced Scientific Research, India, 2007

B.Tech. (Hons.) Biotechnology, Vellore Institute of Technology University, India, 2007

Publications:

JOURNAL PUBLICATIONS:

1.        Microfluidic bioprinting for organ-on-a-chip models; Fang Yu, D. Choudhury*, Drug Discovery Today, March 2019

2.        Engineering Microfluidic Organ-on-Chip Platforms; Fang Yu, Walter Hunziker, D. Choudhury*,  Micromachines, 201910(3), 165; (Invited article)  * Co-corresponding author

3.        The Arrival of Commercial Bioprinters - Towards 3D Bioprinting Revolution!; D. Choudhury*, S. Anand, M. W. Naing* International Journal of Bioprinting, June 2018 (Invited article) * Co-corresponding authors

4.        Organ-Derived Decellularized Extracellular Matrix: A Game-Changer for Bioinks Production? D. Choudhury*, Han W. T., T. Wang, M. W. Naing*  Trends in Biotechnology, April 2018 (Invited article)* Co-corresponding authors

5.        Microfluidics Platforms for Modelling Biological Barriers; F. Yu, N. D/O S. Kumar, D. Choudhury*, L. C Foo, S. H. Ng Drug Discovery Today, Jan 2018. (Invited article) * Corresponding author

6.        Neuromodulatory circuit effects on Drosophila feeding behaviour and metabolism; A. Eriksson, M. Raczkowska, R. Navawongse, D. Choudhury, J. C. Stewart, Z. Wang, A.Claridge-Chang; Scientific Reports, Aug 2017

7.        On-Chip Two-photon Metabolic Imaging for Drug Toxicity Testing; Fang. Yu, Yinghua Qu, D. Choudhury, C. Iliescu, Z. Wang, S. Zhuo, H. Yu; Volume 11, Issue 3, Biomicrofluidics 2017  

8.        Drosophila learn efficient paths to a food source; R. Navawongse*; D. Choudhury*; M. Raczkowska; J.C Stewart; T. Lim; M. Rahman; A.G.G. Toh; Z. Wang; Volume 131, 2016, Pages 176–181 Neurobiology of Learning and Memory;* Co-first authors

9.        Extent of mismatch between the period of circadian clocks and light/dark cycles determines time-to-emergence in fruit flies; P. Yadav, D. Choudhury, M.K., V.K. Sharma; Insect Science, 2014; DOI: 10.1111/1744-79

 10.     Scalable cell alignment on optical media substrates; G. A. Chukwuemeka, D. Choudhury, H. Li, A. Fraiszudeen, K. Y. Peh, Y. C. Toh, S. H. Ng, H. L. Leo, H. Yu; Volume Vol.34, No.21; Pages pp.5078-5087; Biomaterials 2013

 11.     Fish and Chips: A microfluidic perfusion platform for monitoring zebrafish development; D. Choudhury, D.v Noort, C. Iliescu, B. Zheng, S. Korzh, V. Korzh and H. Yu; Lab on a Chip, 2011 (Cover Page and Media Highlights by A*STAR)

 12.     Exploitation of Physical and Chemical Constraints for Three-Dimensional Microtissue Construction in Microfluidics; D. Choudhury, X. Mo, C. Iliescu, and H. Yu; Biomicrofluidics, 2011 

 13.     Galactosylated cellulosic sponge for multi-well drug safety testing; B. Nugraha, X. Hong, X.  Mo, L. Tan, W. Zhang, P. Mak. Chan, C. H. Kang, Y. Wang, L. T. Beng, W. Sun, D. Choudhury, J. M. Robens, M. McMillian, J. Silva, S. Dallas, C.H. Tan, Z. Yue, Hanry Yu; Biomaterials, 2011, 32(29):6982-94.

14.     Rapid construction of mechanically- confined multi- cellular structures using dendrimeric intercellular linker; X. Mo, Q. Li, L.W.Y Lui, B. Zheng, C.H. Kang, B. Nugraha, Z. Yue, R.R. Jia, H.X. Fu, D. Choudhury, T. Arooz, J. Yan, C.T. Lim, S. Shen, C. H. Tan, H. Yu; Biomaterials; 2010; 31(29):7455-67.

 15.     Cell culture on MEMS platforms: A review; M. Ni, W. H. Tong, D. Choudhury, N.A.A. Rahim, C. Iliescu, H. Yu; International Journal of Molecular Sciences; 2009; 0(12):5411-41.

 

CONFERENCE PRESENTATIONS:

  1. D. Choudhury et al. Building a Low-cost Desktop Bioprinter; TERMIS WORLD CONGRES, Sep 4-7 2018, Kyoto 
  2. D. Choudhury et al. Adapting Commercial Projection SLA system for Printing Live Cell-Laden Hydrogels; TERMIS – NA, 3-6 Dec 2017, Charlotte, Oral presentation 
  3. D. Choudhury et al. Comparison between physical and chemical preservation methods for decellularized porcine tissue; 10th World Biomaterials Congress; 17-22 May 2016, Canada  
  4. D. Choudhury et al.  Microfluidic Platform for feeing and simultaneous activity monitoring of Drosophila; Lab-on-a-Chip Asia; 19-20 Nov 2015; Singapore (Invited Oral Presentation)
  5. D. Choudhury et al. ESPRESSO CHIP- Microfluidic Capillary Feeder with Integrated Activity Monitoring Chamber for Drosophila; MicroTAS 2015; 25-29 Oct 2015; Korea
  6. D. Choudhury et al. Fly-on-Chip: A microfluidic platform for the dynamic control of Drosophila feeding; Lab-on-a-Chip World Congress 2014; 8-19 Sep 2014; USA.
  7. D. Choudhury et al., A microfluidic device for studying drug toxicity in developing zebrafish embryos, The 6th International Conference on Microtechnologies in Medicine and Biology, 4-6 May 2011, Lucerne, Switzerland.
  8. D. Choudhury et al., Development of a predictive physiologically based pharmacokinetic microfluidics chip International Symposium on Microchemistry and Microsystems, May 28-30, 2010, HKUST, Hong Kong. 

 

Awards:

GRANTS RECEIVED   

1.        4th JCO CDA Grant Awarded (Ongoing)- Dynamic in vitro blood-brain barrier model to understand cellular interactions for drug design; Duration- 3 years (1st Dec 2015-30th June 2019), Quantum – S$750K; PI- Dr Lynette C Foo/Prof Walter Hunziker (IMCB A*STAR), Co-Investigators- Dr Deepak Choudhury & Dr Ng Sum Huan Gary (SIMTech A*STAR)

2.        AME YIRG 2017 (Ongoing) - Development of a Novel Bioink with 3D Pore-Lattice Microstructures using Microfluidic DrOpleTs (MicroDOTs Bioinks) – 3 years – (April 2018 – March 2021), Quantum – S$240K; PI - Dr Christopher Tostado (NUS), Co-I – A/P Toh Yi-Chin, Collaborators Dr Deepak Choudhury & Dr Jeremy Teo

3.        Exploit Technologies Gap-Funded Project: Intelligent Wellness Prototyping Ref.No: ETPL/14-R15GAP-0014c (Follow up from Intelligent Wellness Ideation & Design Thinking –BOOTCAMP, Oct 2014)