Cardiometabolic diseases are a leading cause of morbidity and mortality in both the developing and developed countries. Led by Dr. Roshni Singaraja, our group is interested in translational research with a focus on identification and functional characterization of pathways involved in cardiometabolic disease. Our aim is to identify novel genes, validate the novel genes utilising human genetic association studies, and bridge the gap between the human association studies and functional mechanisms utilizing human investigative medicine studies, animal models and in vitro studies relevant to the disease states of diabetes mellitus, atherogenic dyslipidemia and cardiovascular disease.