About the speaker: Janine Kruit received her PhD from the University of Groningen, the Netherlands in 2006 on the role of the intestine in HDL metabolism. She then moved to the Hayden laboratory in Vancouver to study the role of cholesterol in pancreatic islet function. Since March 2014, she is a junior group leader at the department of Paediatrics at the University Medical Center Groningen (UMCG), the Netherlands. The general aim of her research is to understand molecular mechanisms that lead to β-cell dysfunction in vivo with the ultimate goal to develop strategies to improve β-cell function in diabetes. She uses transgenic mouse models and cell systems to perform in-depth analysis of systemic physiology, cellular biochemistry, intracellular signal transduction and transcriptional regulation. Her latest research focuses on the role of DNA damage in the pathogenesis of diabetes.
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