"It takes a village to raise a child and bring it to life. The same is true for innovation and science."
How Pauline Tay shaped Singapore’s biomedical and deep-tech ecosystem, turning research into impact through collaboration and trust.
Pauline Tay is a biomedical researcher, policymaker, and ecosystem builder. She has spent her career translating research into real-world impact, from shaping national programs to nurturing startups to championing innovation across public and private sectors. But more than any title, Pauline sees herself as part of a community: one that builds together, shares lessons, and keeps the dream going.
In this conversation, she reflects on her journey from early A*STAR days to her work today in healthcare innovation.
We asked Pauline to look back on the moments and milestones that defined her career. Here’s what she shared.
What’s your first memory of A*STAR?
What drew you to science?
You began your career at A*STAR in research management. What was that like?
What made you return to the lab for your PhD?
Was your goal always commercialization?
Not really – but it was to bring science to real-world practicality and impact. And to do that, you need to go through a process of commercialisation, to make things tangible and usable.
I never wanted to stay in academia. I wanted to take research beyond the lab to turn it into products, services, and real-world change. But in those days, pathways weren’t clear. So, during my postdoc I did part-time attachments with ETPL (Exploit Technologies Private Limited), now A*STAR I&E (Innovation & Enterprise) to learn about intellectual property, tech transfer, commercialisation and investments from the ground up.

Tell us about Innovation Partner for Impact (IPI).
Then came NRF. What shifted for you there?
I realized that helping companies one-on-one alone wasn’t enough, if the broader ecosystem wasn’t ready to continue supporting them.
There needed to be a value chain of companies and supporting structures that sustains itself. So, I moved to NRF (National Research Foundation) to work on deep tech innovation and enterprise policy – changing the landscape, building value chains, creating funding structures, and supporting innovation at a systems level. That experience made me realise the importance of systems thinking. It was planting seeds with no guarantee they’d grow. But we created a nurturing garden to spur their growth, and they did.
You eventually moved into the private sector. Why?
What’s your role today?

What makes a good candidate for support at NHIC?
What advice would you give to early-career researchers or A*STAR scholars today?
Who or what has shaped your thinking the most?
Mentors. Chairman Philip Yeo and many of my bosses at A*STAR and NRF taught me to keep moving even when the road wasn’t built yet.
Others taught me about leadership, grooming future talent and succession planning. How to keep the dream alive and pass the torch on when you step aside. For our ecosystem to thrive for generations to come, we must keep building the future and passing the baton on for Singapore.


