"Optimise for the most interesting thing."
How Xinhong Lim’s journey through A*STAR shaped a career across science, venture capital and national development.
Xinhong Lim’s career spans stem cell research, venture capital, and urban development at a national scale. As one of the first A*STAR scholars, he grew with the agency from its earliest days.
However, Xinhong’s journey defies easy categorisation. From building skincare breakthroughs in Singapore to helping design a next-generation city in Bhutan, his story reflects the power of curiosity, conviction, and keeping an open mind.
In this conversation, he reflects on the early moments that shaped his path, from an A*STAR scholarship to high-stakes roles across research, finance and government. His story spans labs and boardrooms, ideas and infrastructure, and shows what can happen when expertise is paired with adaptability.
We asked him to look back on the moments, decisions and lessons that shaped his journey — here’s what he shared.
What comes to mind when you hear A*STAR?
Three things: talent, technology, and transfer. A*STAR has always been about identifying top talent and enabling them to develop technologies that matter. But the third part — transfer — is critical. That’s where I spent most of my time, making sure research doesn’t stay in the lab, but moves into companies, products and impact.
How did you first get involved with research?
I was always drawn to biological systems. I took part in science programmes where we had to generate our own research questions and test them. It was rudimentary — one project asked whether water coolers near bathrooms were less hygienic — but it taught me how to think like a scientist. That process stuck with me.
How did you end up joining A*STAR?
I was originally on an Economic Development Board (EDB) and GlaxoSmithKline (GSK) EDB-GSK scholarship to pursue biomedical sciences. But then A*STAR was formed, and they moved all the bio scholars over. I was excited. They made it clear we would be the vanguard — the next generation of Singapore scientists. That offer to be part of something new and ambitious was very compelling to me.
What was your research focus?
I studied skin stem cells. My PhD was at Stanford, where I made discoveries about how stem cells in skin sustain themselves. That work ended up being published in Science. It helped me return to Singapore as a Junior Investigator at the Institute of Medical Biology. There, I continued research in skin biology and signalling pathways.
When did the entrepreneurial spark kick in?
It was always there. I ran small ventures even while in school. But at Stanford, the startup culture is everywhere. I took a certificate course at the Graduate School of Business in innovation and entrepreneurship. I also spent time with A*STAR’s tech transfer office learning about patents and business development. That foundation stayed with me.
Did you apply that mindset at A*STAR?
Definitely. I worked with a senior dermatologist and together we secured industry funding to explore acne-related research. We were developing new actives that could go into skincare products. At the same time, I started consulting with Vickers Venture Partners. That began with scientific due diligence but grew into deeper involvement. Eventually I was sitting in board meetings and helping with commercial strategy.
When did you officially make the shift to VC?
Embrace the breadth. A*STAR is not just about research. It’s policy, public service, research management, enterprise, and beyond. If you’re open, you’ll gain a wide-angle view of how science becomes strategy, and how technology creates real change.
How did Bhutan come into the picture?
It started with a chance meeting. I met His Majesty the King of Bhutan at a wedding, where we spoke about science and innovation. During the pandemic, we stayed in touch. In 2023, he shared his vision to build a new city — one that would modernise Bhutan’s economy while staying rooted in its values. He asked if I would help bring that vision to life.
What was your role in Bhutan?
I joined as employee number one of the new initiative. I helped set up the legal and economic foundations of the city, advised on policy, and worked closely with His Majesty. It was unlike anything I had done before. I split my time between Bhutan and Singapore, so my family could remain anchored while I pursued the opportunity.
What advice would you give to someone at the start of their journey?
Optimise for the most interesting thing. That is my north star. Do not be too anxious about where it will take you. Focus on learning, stay curious, and build useful skills. You can always deepen your expertise, but stay open to where it might be deployed.
What advice would you give to someone at the start of their journey?
Optimise for the most interesting thing. That is my north star. Do not be too anxious about where it will take you. Focus on learning, stay curious, and build useful skills. You can always deepen your expertise, but stay open to where it might be deployed.
What’s next for you?
I have stepped back from my role in Bhutan and am exploring what comes next. I am open to new opportunities and excited for the next chapter.
How can people reach you?
LinkedIn is the best way to connect.
