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    • Publicity Highlights

    Tackling drug-resistant tuberculosis strains

    16 Nov 2017
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    Researchers from A*STAR’s Singapore Immunology Network (SIgN) have found that activating the enzyme Sirtuin-1 in the body can boost the body’s ability to fight drug-resistant tuberculosis. Sirtuin-1 is known to regulate metabolic function in the body and plays an important role in ageing and inflammation. Sirtuin-1 activators can also be found in red wine and grape skins. Dr Amit Singhal, who led the study, said that when Sirtuin-1 is activated in the body, it induces the tuberculosis bacteria in the body to devour themselves, in a process known as autophagy.

    Read more below:

    • Lianhe Zaobao: Increasing the body’s immunity against drug-resistant tuberculosis
    • TODAY Online: A*Star scientists find new way to tackle drug-resistant tuberculosis