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SINGAPORE RESEARCHERS DEVELOP AI TOOL TO PREDICT LIVER CANCER RECURRENCE
Dr Joe Yeong, Principal Investigator at A*STAR IMCB, with copies of Nature featuring the TIMES study on the cover. The study presents an AI-powered scoring system to predict liver cancer recurrence more accurately and earlier, offering new hope for timely intervention. (Photo: The Straits Times / Brian Teo).
SINGAPORE — Scientists from A*STAR Institute of Molecular and Cell Biology (A*STAR IMCB) and Singapore General Hospital (SGH) developed an artificial intelligence (AI)-powered scoring system capable of predicting the recurrence of hepatocellular carcinoma (HCC), the most common form of liver cancer. Named the Tumour Immune Microenvironment Spatial (TIMES) score, this study was recently featured as the cover article in the scientific journal Nature—a recognition that underscores the global significance and impact of the research.
The researchers validated the TIMES system using samples from 231 patients across five hospitals. They have now made the technology accessible through a free web portal for research use, with plans underway to integrate TIMES into routine clinical workflows.
Nature 640, 1031–1041 (2025). https://doi.org/10.1038/s41586-025-08668-x
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