Cell & Molecular Therapy Division

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Did you know that we can cure or prevent diseases using cells and modified molecules?

The IMCB Cell & Molecular Therapy (CMT) Division is dedicated to advance the science and technologies for curing or preventing diseases using cells and modified molecules. It aims to build a cutting-edge, global leading biomedical research program to understand the complexity of cellular systems and to utilise cells and molecules to transform therapy approaches.


We are a multidisciplinary research team of scientists, bioengineers, and clinicians working at the forefront of Regenerative Medicine, Immuno-oncology, and Molecular Engineering. Our research focuses on understanding how diseases start, progress, and respond to treatments. This is enabled by adopting a cross-disciplinary approach for engineering cells and biomolecules to make highly functional and potent therapeutics.

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Regenerative Medicine
Our team has built up core capabilities in the differentiation of specialized cell types, stem cell expansion and banking, regeneration of complex tissues and disease modelling using 3D organoids, rodent and non-human primate models.
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Immuno-Oncology
We leverage multi-omics profiling to develop immunotherapy products with enhanced tumor-killing efficacy.
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Molecular Engineering
We modify diverse biomolecules (mitochondria, extracellular vesicles, RNAs and peptides) for therapeutic, screening, or disease diagnostic purpose.

Our Core Investigators

Adrian TEO
Jayantha GUNARATNE
Sherry AW
Leslie BEH
Christopher BROWN
John E CONNOLLY
Farid GHADESSY
Walter HUNZIKER
  • Walter HUNZIKER
  • Epithelial Cell Polarity in Disease and Tissue Regeneration Laboratory
Qi Jing LI
  • Qi Jing LI
  • Translational T Cell Biology and Therapeutics
 Jonathan LOH Yuin-Han
Boon Seng SOH
Xinyi SU
  • Xinyi SU
  • Regenerative therapeutics for retinal diseases
  • Translational Retinal Research Laboratory
Dave WEE
  • Dave WEE
  • RNA modulations for therapeutics
Fong Tian WONG
Yun XIA
  • Yun XIA
  • Kidney Regeneration and Disease Modelling