Wee Wei TEE

Wee Wei Tee is a Senior Principal Investigator and Deputy Division Director (Cancer Signalling and Therapy) at the Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR)  and Assistant Professor at the Department of Physiology at National University of Singapore (NUS). 

Wee Wei was mentored by Prof. Azim Surani at the University of Cambridge, UK and obtained his PhD with a Wellcome Trust PhD scholarship. A developmental biologist by training, Wee Wei then joined the laboratory of Prof. Danny Reinberg, a renowned chromatin biochemist and Howard Hughes Investigator at New York University School of Medicine, for his postdoctoral training. 

The work in Wee Wei’s lab at IMCB focuses on disease epigenetics, cancer therapeutics, ageing, and regenerative medicine. His lab employs various genomic tools to interrogate genome-wide changes in chromatin states during development and disease, and utilises varied experimental tools such as bioinformatics, gene-editing, biochemistry as well as animal models and cell-based screens to uncover disease mechanisms. His lab is also actively involved in drug development efforts from target discovery to therapeutics development.

Wee Wei’s  lab aims to work towards formulating a comprehensive understanding of the epigenetic basis of human diseases, and we seek to achieve this by interfacing basic mechanistic studies with translational research.