PUBLICATIONS & PRESS RELEASES

3. Ethnic differences in atrial fibrillation in patients with heart failure from Asia-Pacific

4. Toll-like Receptor 7 Deficiency Promotes Survival and Reduces Adverse Left Ventricular Remodeling After Myocardial Infarction

5. Combining Circulating MicroRNA and NT-proBNP to Detect and Categorize Heart Failure Subtype

1. MicroRNA-143 modulates the expression of Natriuretic Peptide Receptor 3 in cardiac cells

2. Plasma Ceramides as Prognostic Biomarkers and Their Arterial and Myocardial Tissue Correlates in Acute Myocardial Infarction

3. Cardiac metabolic modulation upon low‐carbohydrate low‐protein ketogenic diet in diabetic rats studied in vivo using hyperpolarized 13C pyruvate, butyrate and acetoacetate probes;

Diabetes, Obesity & Metabolism. 5 Dec 2018. DOI: 10.1111/dom.13608

4. Heart Failure With Preserved Ejection Fraction in the Young

5. Targeting Chondroitin Sulfate Glycosaminoglycans to Treat Cardiac Fibrosis in Pathological Remodeling
Circulation. 2018 Jun 5;137(23):2497-2513

6. Mortality Associated With Heart Failure With Preserved Versus Reduced Ejection Fraction In A Prospective International Multi-Ethnic Cohort Study
Eur Heart J. 2018 May 21;39(20):1770-1780

7. Prevalence, clinical correlates and outcomes of anaemia in multiethnic Asian patients with heart failure with reduced ejection fraction
ESC Heart Failure 2018 Mar 31. doi: 10.1002/ehf2.12279. [Epub ahead of print]

8. Plasma Ceramides as Prognostic Biomarkers and Their Arterial and Myocardial Tissue Correlates in Acute Myocardial Infarction
JACC: Basic to translational science; Vol 3, Issue 2, April 2018

9. Distinctive Molecular Signature and Activated Signaling Pathways in Aortic Smooth Muscle Cells of the Patients with Myocardial Infarction
Atherosclerosis 2018 Apr; 271:237-244

10. MicroRNA-143 modulates the expression of Natriuretic Peptide Receptor 3 in cardiac cells
Scientific Reports; Volume 8, Article number: 7055 (2018)

11. Multimorbidity in patients with heart failure from 11 Asian regions: A prospective cohort study using the ASIAN-HF registry
PLoS Med 15(3)

12. N-terminal pro-B-type Natriuretic Peptide and Prognosis in Caucasian versus Asian Patients with Heart Failure
ESC Heart Failure 2018 Apr; 5(2):279-287

13. Chronic obstructive pulmonary disease and β-blocker treatment in Asian patients with heart failure
ESC Heart Fail. 2018 Apr;5(2):297-305

14. A risk assessment score and initial high-sensitivity troponin combine to identify low-risk of acute myocardial infarction in the emergency department
Academic Emergency Medicine Journal; 2018 Apr; 25(4):434-443

15. Daily Home BNP Monitoring in HF for prediction of impending clinical deterioration: Results from the HOME HF study

Cardiovasc Res. 2017 March; 113(3):298-309

2016
1. Pulmonary hypertension in heart failure with preserved ejection fraction: a plea for proper phenotyping and further research

Eur Heart J. 2016 Dec 23. 0:1-5

2. Right ventricular dysfunction in heart failure with preserved ejection fraction: a systematic review and meta-analysis

Eur J Heart Fail. 2016 Dec; 18(12):1472-1487

3. Atrial Fibrillation in Heart Failure With Preserved Ejection Fraction: Association With Exercise Capacity, Left Ventricular Filling Pressures, Natriuretic Peptides, and Left Atrial Volume
JACC Heart Fail. 2016 Dec. 5(2):92-98

4. Prevalence and Clinical Significance of Diabetes in Asian Versus White Patients With Heart Failure
JACC Heart Fail. 2016 Nov 30; S2213-1779(16):30501-7

5. The International Human Epigenome Consortium: A blueprint for scientific collaboration and discovery

Cell. 2016 Nov 17; 167(5):1145-1149

6. Heart Failure With Preserved Ejection Fraction and Atrial Fibrillation: Vicious Twins

J Am Coll Cardiol. 2016 Nov 15; 68(20):2217-2228

7. Serum ferritin and risk for new-onset heart failure and cardiovascular events in the community

Eur J Heart Fail. 2016 Oct 19; 19(3):348-356

8. Aberrant Splicing Promotes Proteasomal Degradation of L-type CaV1.2 Calcium Channels by Competitive Binding for CaVβ Subunits in Cardiac Hypertrophy

Sci Rep. 2016 Oct 12; 6, article number:35247

9. Influence of Ethnicity, Age, and Time on Sex Disparities in Long-Term Cause-Specific Mortality After Acute Myocardial Infarction
J Am Heart Assoc. 2016 Oct 6; 5(10)

10. Random Plasma Glucose Levels and Cardiovascular Risk

JAMA Cardiol. 2016 Oct 1;1(7):823-824

11. A simplified, Landendorff-free method for concomitant isolation of viable cardiac myocytes and non-myocytes from the adult mouse heart

Circ Res 2016 Sep 30;119(8):909-20

12. Ethnic differences in the association of QRS duration with ejection fraction and outcome in heart failure
Heart. 2016 Sep 15;102(18):1464-71

13. A Test in Context: Neprilysin: Function, Inhibition, and Biomarker

J Am Coll Cardiol. 2016 Aug 9; 68(6):639-53

14. Regional and ethnic differences among patients with heart failure in Asia: the Asian sudden cardiac death in heart failure registry

Eur Heart J (2016) Aug 7; 37(41):3141-3153

15. A genomic and epigenomic comparison of fetal and adult human cardiac fibroblasts reveal novel key transcription factors in adult cardiac fibroblasts

JACC Bas Trans Sci. July 2016; 1(7):590-602

16. Three-Dimensional Tricuspid Annular Motion Analysis from Cardiac Magnetic Resonance Feature-Tracking

Ann Biomed Eng. 2016 Jul 19; 44(12):3522-3538

17. AAV9 delivery of shRNA to the mouse heart Curr Protoc Mol Biol. 2016 Jul 1; 115:23.16.1-9

10. Women Undergoing Coronary Angiography for Myocardial Infarction or Who Present With Multivessel Disease Have a Poorer Prognosis Than Men
Angiology 2015 Sep 7

11. Electrocardiographic Criteria for Left Ventricular Hypertrophy in Asians Differs From Criteria Derived From Western Populations—Community-based Data from an Asian Population.
Ann Acad Med Singapore 2015 Aug; 44(8):274-283

12. Cardiac Endothelium-Myocyte Interaction: Clinical Opportunities for New Heart Failure Therapies Regardless of Ejection Fraction
Eur Heart J 2015 Aug 14; 36(31):2050-2060

13. Diabetic Cardiomyopathy: An Expression Of Stage B Heart Failure With Preserved Ejection Fraction
Diabetes & Vascular Disease Research Jul 2015, Vol. 12(4):234–238

14. The Relationship among Carotid Artery Remodeling, Cardiac Geometry, and Serum N-terminal Pro-B-type Natriuretic Peptide Level in Asymptomatic Asians: Sex-differences and Longitudinal GEE study.
PLOS ONE 2015 Jul 1; 10(7)

15. Inter-Ethnic Differences in Quantified Coronary Artery Disease Severity and All-Cause Mortality among Dutch and Singaporean Percutaneous Coronary Intervention Patients
PLOS ONE 2015 Jul 6; 10(7)

16. Heart Failure In Southeast Asia: Facts And Figures (Invited Editorial)
ESC-Heart Failure June 2015, Issue 2, Volume 2:46-49

17. Experimental heart failure modelled by the cardiomyocyte-specific loss of an epigenome modifier, DNMT3B
J Mol Cell Cardiol 2015 May; 82:174-83

18. Natriuretic peptide receptor 3 (NPR3) is regulated by microRNA-100
J Mol Cell Cardiol 2015 May; 82:13-21

19. Circulating microRNAs in heart failure with reduced and preserved left ventricular ejection fraction
Eur J Heart Fail. 2015 Apr;17(4):393-404

20. Patient Selection in Heart Failure With Preserved Ejection Fraction Clinical Trials
J Am Coll Cardiol 2015, 65(16):1668–1682

21. Heart failure with preserved ejection fraction in women: the Dutch Queen of Hearts program
Neth Heart J. 2015 Feb; 23(2):89-93

22. Iron deficiency in a multi-ethnic Asian population with and without heart failure: prevalence, clinical correlates, functional significance and prognosis
Eur J Heart Fail. 2014 Oct; 16(10):1125-32

23. Asian Sudden Cardiac Death in Heart Failure (ASIAN-HF) registry
Eur J Heart Fail., Aug 2013, 15(8):928–936

24. The Singapore Heart Failure Outcomes and Phenotypes (SHOP) Study and Prospective Evaluation of Outcome in Patients With Heart Failure With Preserved Left Ventricular Ejection Fraction (PEOPLE) Study: Rationale and Design
J Card Fail. 2013 Mar;19(3):156-62

25. Growth differentiation factor 15, ST2, high-sensitivity troponin T, and N- terminal pro brain natriuretic peptide in heart failure with preserved vs. reduced ejection fraction
Eur J Heart Fail. 2012 Dec; 14(12):1338-47

Posters

1. Left atrial strain by cardiac magnetic resonance feature tracking is a novel diagnostic biomarker of heart failure with preserved ejection fraction