iCORE Genomics

Established over a decade ago, the iCORE Genomics, previously known as integrated Genome Analytics Platform (iGAP) represents the synergistic integration of iCORE's capabilities.

Together with the Integrated Genomics Platform (IGP) and the Bioinformatics Core (BC) from GIS, iCORE Genomics leverages extensive, deep-rooted expertise in cutting-edge Next Generation Sequencing (NGS) technologies to provide users with comprehensive, end-to-end genomic solutions.

Key Services

We offer a full spectrum of genomic services, including:

  • Advanced microarray analysis (ie genotyping and methylation arrays)
  • Meticulous NGS library preparation
  • Comprehensive short-read and long-read sequencing

Key Applications

Genotyping Solutions

  • Ideal for high-throughput, cost-effective analysis, our genotyping services excel at:

Genome-Wide Association Studies (GWAS)

  • Identifying genetic variants associated with complex traits and diseases across large populations.

Fine Mapping

  • Pinpointing causal variants within regions of interest identified through GWAS.

Population Genetics

  • Assessing genetic diversity, ancestry, and evolutionary relationships.

Agricultural Genomics

  • Marker-assisted selection and trait mapping in plant and animal breeding programs.

Methylation Profiling

  • Targeted analysis of DNA methylation patterns across the genome.

Next-Generation Sequencing (NGS) Application

For deeper, unbiased exploration, our NGS services enable:

  • Whole Genome Sequencing (WGS): Comprehensive detection of single nucleotide variants (SNVs), insertions/deletions (indels), and structural variants across the entire genome.
  • Whole Exome Sequencing (WES): Cost-effective, focused analysis of protein-coding regions for rare disease research and variant discovery.
       

Key Equipment

  • Illumina iScans
  • Illumina Miseq
  • Illumina NextSeq
  • Illumina NovaseqX
  • Nanopore GridION
  • PromethION
Illumina miseq
Illumina Nextseq

Our People

iCORE Genomics Platform is supported by a dedicated team of five who provide responsive, end‑to‑end support for your sequencing needs. From study planning to sequencing delivery, we work closely with users to ensure efficient, reliable, and high‑quality service tailored to your research goals.
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Team Members: Mok Shi Qi (Left); Heng Khai Koon (Middle); Ng Poh Yong (Right); Meah Wee Yang and Peh Su Qin (Not in photo)
Contact us to learn more about our platforms, services and how our team can support your research needs.