iCORE Genomics

01 — Array-Based Genomics

High-throughput array technologies for genome-wide molecular profiling and genetic variation analysis.

• Genotyping arrays
• DNA methylation arrays
• Genome-wide variant profiling
• Copy number and cytogenetic analysis
• Population and ancestry profiling
• Array data quality control and analysis

02 — Short-Read Sequencing

High-throughput sequencing for accurate characterization of genomic, transcriptomic, and microbial sequences.

• Short-read library preparation
• Whole-genome sequencing
• Whole-exome sequencing
• RNA sequencing
• Targeted sequencing
• Metagenomic library preparation
• Sequencing data processing and bioinformatics analysis

03 — Long-Read Sequencing

Long-read sequencing enables resolution of genomic regions and biological features that can be challenging to characterise using conventional short-read approaches.

• Long-read library preparation
• Whole-genome sequencing
• De novo genome assembly
• Full-length transcript sequencing
• Epigenetic and nucleotide modification analysis
• Structural variant analysis
• Haplotype phasing
• Long-read metagenomics

04 — Library Preparation

Optimised library preparation workflows supporting a broad range of sequencing applications and experimental designs.

• DNA library preparation
• RNA library preparation
• Whole-genome and whole-exome libraries
• Targeted sequencing libraries
• Amplicon libraries Metagenomic libraries
• Long-read sequencing libraries
• Low-input and challenging sample workflows

Library preparation can be tailored to sample type, sequencing technology, application, and desired analytical outcome.

05 — Bioinformatics & Data Analysis

Transforming high-dimensional genomic data into biologically meaningful insights through robust computational analysis.

Bioinformatics Capabilities

• Genomic Analysis
  • Sequence quality control
  • Read Alignment and mapping
  • Variant calling and annotation
  • SNP and indel analysis
  • Structural variant detection
  • Copy number analysis
  • Haplotype phasing

• Transcriptomic Analysis
  • RNA-seq analysis
  • Differential gene expression
  • Transcript and isoform analysis
  • Alternative splicing
  • Functional enrichment analysis

• Population & Genetic Analysis
  • Population structure
  • Ancestry analysis
  • Genetic diversity
  • Genome-wide association analysis
  • Phylogenetic analysis

• Microbial & Metagenomic Analysis
  • Taxonomic profiling
  • Microbial community analysis
  • Metagenomic classification
  • Pathogen identification
  • Comparative microbial genomics

• Interpretation
  • Functional annotation
  • Pathway analysis
  • Biological interpretation
  • Integrated genomic data analysis

Array-Based Genomics

• Genotyping and genetic variation profiling
• Genome-Wide Association Studies (GWAS)
• Population Genetics and Ancestry
• Complex Disease and Autoimmune Disease Research
• Cytogenetics
• Copy Number Variation (CNV) Analysis
• Epigenetic and DNA Methylation Studies

Short-Read Sequencing

• Whole-Genome Sequencing (WGS)
• Whole-Exome Sequencing (WES)
• RNA Sequencing (RNA-seq)
• Targeted Gene Panels
• Cancer Genomics
• Metagenomics and Microbiome Profiling
• Genetic Variant Discovery and Characterisation

Short-read sequencing provides high-throughput, high-accuracy genomic profiling for applications requiring comprehensive sequence coverage and robust variant detection.

Long-Read Sequencing

• De Novo Genome Assembly
• Transcriptomics and Isoform Sequencing
• Epigenetics and DNA Modification Analysis
• Structural Variant Detection
• Haplotype Phasing
• Metagenomics
• Pathogen Genomics and Surveillance

Long-read approaches provide enhanced resolution of repetitive regions, complex genomic structures, structural variation, and full-length transcripts, enabling deeper characterisation of genome architecture and function.

Applications Across Genomics Research

Our integrated capabilities support a broad spectrum of genomic research areas:

From Sample to Insight, An Integrated Genomics Workflow

1. Experimental Design
2. Sample Processing
3. Array / Library Preparation
4. Short-Read / Long-Read Sequencing
5. Primary Data Processing
6. Bioinformatics Analysis
7. Integrated Genomic Interpretation

One Platform. Multiple Technologies. Integrated Analysis.

By combining array-based profiling, short-read sequencing, long-read sequencing, and bioinformatics, ICORE Genomics and GIS-CORE provide researchers with the flexibility to select the most appropriate technology—or integrate multiple technologies—to address complex biological questions.