Skin MedTech and Biophotonics

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The Skin MedTech and Biophotonics Theme aims to develop and apply advanced optical, imaging, sensing and computational technologies to enable non-invasive, quantitative and clinically translatable insights into skin biology and disease. 

Our technologies are designed to deliver high-resolution structural, functional, and biochemical information, supporting precision diagnostics, therapy evaluation and personalized interventions. We aim to transform how skin is measured, monitored and treated across clinical, research and consumer settings.

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Non-invasive Optical and Multimodal Imaging

We develop advanced optical and multimodal imaging technologies to non-invasively visualize the structural, functional and biochemical properties of skin and soft tissues in-vivo. By integrating biophotonics, photoacoustic imaging and ultrasound-based approaches, our platforms enable high-resolution, depth-resolved assessment of tissue composition, vascular function and disease status, supporting precision diagnostics and treatment monitoring.

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Wearable and Point-of-Care Technologies

We design wearable and point-of-care optical systems that enable continuous, real-time monitoring and non-invasive intervention beyond the clinic. Combining diffuse optical sensing with flexible, low-cost wearable platforms, we support longitudinal assessment of skin and vascular health, which can be deployed to home-based care and population-scale studies, bridging laboratory-grade measurements to real-world applications.

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Advanced Biosensing and Nanophotonics

Advanced Biosensing and Nanophotonics focuses on highly sensitive biosensing technologies for detecting molecular and biochemical signatures in skin, tissues and body fluids. Leveraging nanophotonics, plasmonics and surface-enhanced spectroscopic techniques, we enable precise biomarker detection and analysis, supporting disease stratification, therapeutic evaluation and the development of next-generation diagnostic tools.

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Digital and Optical Twins of Skin

We develop multiscale digital and optical twins of human skin that integrate biophysical modelling, artificial intelligence and advanced optical simulations. These computational platforms enable predictive modelling of skin ageing, disease progression and treatment response, providing a quantitative framework to interpret experimental data, guide intervention design and accelerate translational research.

Our Investigators