A*STAR Bioprocessing Technology Institute (BTI)

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BTI's Key Focus Areas
BTI's Capabilities

Who We Are

A*STAR Bioprocessing Technology Institute (BTI) focuses on advancing bioprocessing technologies and research over its 35-year history. Our current vision is to Realise Quality Processes for Biomanufacturing, with a strong emphasis on Proteins, Cells, and Nucleic Acids.

BTI’s Key Focus Areas

To achieve BTI’s vision of ensuring Quality Processes for Biomanufacturing, the institute develops innovative research capabilities and advanced biomanufacturing technologies. Modality-specific strategies are key to BTI achieving its mission of developing Singapore's biomanufacturing sector where asset classes are in various stages of maturity and development.

BTI's Core Capabilities

BTI’s core capabilities are systematically organised around its four principal divisions, which oversee 19 Enabling Research Groups, and Technology Platforms and Consortia. The matrix structure of BTI’s divisions enables the swift and flexible assembly of research teams with synergistic capabilities, allowing them to effectively address research and industry problem statements.

Enabling the Next-Gen Tissue Membrane Factory

16 Jan 2026

Growing living cells in a uniform three-dimensional (3D) membrane is valuable for many applications ranging from drug screening to cutting-edge cell and tissue-based therapies and potentially even for food applications such as cultivated meat. Conventional methods rely on complex printing equipment, which are costly and hard to scale up. Our multidisciplinary groups at BTI have developed a simple yet effective spheroid-sheet method that guides small cell spheroids, each containing thousands of living cells, to merge into a large and thin tissue membrane. By mimicking nature’s cell-packing strategy, we make the large-scale, consistent production of tissue membranes more achievable.

Posted in: BTI Research Highlights

Realise Quality Processes for Biomanufacturing

Research Excellence

Industry Collaboration

Talent Development

A*STAR Bioprocessing Technology Institute (BTI)

Who We Are

BTI’s Key Focus Areas

BTI's Core Capabilities

Enabling the Next-Gen Tissue Membrane Factory

Realise Quality Processes for Biomanufacturing

Research Excellence

Industry Collaboration

Talent Development

A*STAR Bioprocessing Technology Institute (BTI)

Who We Are

BTI’s Key Focus Areas

BTI's Core Capabilities

Enabling the Next-Gen Tissue Membrane Factory

A*STAR celebrates International Women's Day