In-depth Insights into Continuous Biomanufacturing Downstream Processing
Continuous biomanufacturing (CM) represents a major advancement in biomanufacturing, offering increased productivity and cost reduction. Multi-column chromatography (MCC) is a key unit operation in CM, playing a critical role in downstream processing. In this study, we employed a full factorial design to examine the impact of critical process parameters during both steady-state and transient phases of MCC. Our findings provide deeper insights into the process dynamics of CM.
