A*STAR PATENTS

According to various embodiments, an image processing device may be provided. The image processing device may include: an input circuit configured to receive input image data including pixels related to varying exposure times; an interpolation circuit configured to determine an output image based on an interpolation based on the input image data; and an output circuit configured to output the output image.

A method and a system for determining an optical eye diagram of a modulated optical beam of an interferometer device, a method of evaluating system performance of electro-optic devices, and a data storage medium having stored thereon data code means for instructing a computing device to execute the methods. The method of determining an optical eye diagram of a modulated optical beam of an interferometer device comprises obtaining AC parameters for one or more modulator structures of the interferometer device at respective DC bias voltages within a predetermined bias voltage range at an operating frequency of the one or more modulator structures from electrical simulation; obtaining a carrier concentration profile from the electrical simulation; obtaining optical parameters for the one or more modulator structures from optical simulation based on the carrier concentration profile; and determining the optical eye diagram of the modulated optical beam based on the AC parameters and the optical parameters.

The present invention provides a sensor for sensing nucleic acid-protein interactions, comprising a noble metal nanoparticle (NP), a double stranded nucleic acid molecule capable of binding with a protein in an aqueous solution and a fluorescent conjugated polymer (CP). The present invention also provides a method for sensing nucleic acid-protein interactions with the sensor as defined above.

A cationic star polymer is disclosed of the general formula (1): wherein w? is a positive number greater than or equal to 3, I? is a dendritic polyester core covalently linked to w? independent peripheral linear cationic polymer chains P?. Each of the chains P? comprises a cationic repeat unit comprising i) a backbone functional group selected from the group consisting of aliphatic carbonates, aliphatic esters, aliphatic carbamates, aliphatic ureas, aliphatic thiocarbamates, aliphatic dithiocarbonates, and combinations thereof, and ii) a side chain comprising a quaternary amine group. The quaternary amine group comprises a divalent methylene group directly covalently linked to i) a positive charged nitrogen and ii) an aromatic ring.

https://patents.google.com/patent/SG10201405426S

According to the invention there is provided methods for inducing pluripotent stem cells in vitro, vectors and compositions for producing the same and methods for using the induced pluripotent stem cell for treating a patient in need of a pluripotent stem cell treatment.

In various embodiments, a stent member is provided. The stent member may include a self-expanding stent frame defining in its expanded position a central annular opening along a longitudinal axis, the opening extending from a first end to a second end of the stent frame. The stent member may include at least one anchoring structure extending radially outwards from the second end of the stent frame. The stent member may further include a biocompatible coating on the stent frame.

There is provided a method of identifying candidate agents capable of modulating interaction between a first polypeptide and a second polypeptide, wherein the first polypeptide is ZO-2/TJP2 or a functional variant thereof and the second polypeptide is a Snail zinc finger transcription factor family member or a functional variant thereof.

A method and system of in vitro developmental toxicity testing comprising the steps of micropatterning an extracellular matrix; growing embryonic stem cells on the micropatterned extracellular matrix in the presence of mesoendodermal induction and testing for change of the geometrical mesoendoderm structure in the presence or absence of a test compound wherein (1) a decrease in mesoendodermal differentiation and/or (2) a change in morphology of the geometrical mesoendoderm structure in the presence of the test compound compared to cells in the absence of the test compound indicates that the test compound is a developmental toxic agent.

A memory device and method comprising a metal oxide material disposed between and in electrical contact with first and second conductive electrodes, and a voltage source configured to apply a plurality of voltage pulses spaced apart in time across the first and second electrodes. For each one of the voltage pulses, an amplitude of the voltage increases during the voltage pulse.