Steven Thng Tien Guan

Steven Thng
A/Prof Steven Thng Tien Guan
Chief Dermatologist

Research themes: Inflammation & Immunity, Medical Technology, Pigmentation

Dr Steven Thng graduated from National University of Singapore in 1992 and went on to pursue his interest in Humanitarian and Disaster medicine with the Singapore Armed Forces from 1992 to 2002. After completing his dermatology training in Singapore, Dr Steven Thng went on to Amsterdam Medical Centre, Netherlands, to continue his training in pigmentary disorder, under Professor Westerhof. Upon returning from his training, Dr Steven Thng started the pigment clinic in National Skin Centre as well as set up the melanocyte culture lab to start his work on cultured melanocytes grafting for vitiligo patients.

Currently, Dr Thng is the head of the pigment clinic, in charge of managing all complex pigmentary disorders in National Skin Centre, and he is also the principal surgeon for tissue grafting for vitiligo. In 2012, he has also started a research clinic for hyperpigmentary disorders exploring novel ways to manage difficult hyperpigmentary conditions. He took over as Executive Director of Skin Research Institute of Singapore from Jan 2017 to Feb 2020, and was responsible for the transformation of SRIS from a virtual institute to a dynamic institute, working on 4 main multi-institutional, interdisciplinary research programs of chronic wound, acne, skin microbiome and atopic dermatitis. His current research interest is on skin pigmentary disorder, novel drug delivery systems, as well as advanced imaging for skin cancer and skin diseases. He has translated much of his research to improve patient care in dermatology.

Currently, he has been serving as the Chief Dermatologist of Skin Research Institute of Singapore from Feb 2020.

For his dedication in research and patient care, he was awarded Excellence in Public Service Award in 2013, Healthcare Humanity Award in 2014, Singapore Clinician Investigator Award in 2015 and 2016

Research interests
Skin Pigmentary Disorder (Mainly into treatment of both hyper and hypopigmentary disorders)
Atopic Dermatitis
In-vivo Skin Imaging
Skin Delivery Systems

Selected publications
Chuah SY, Attia ABE, Ho CJH, Li X, Lee JS, Tan MWP, Yong AA, Tan AWM, Razansky D, Olivo M, Thng STG. Volumetric Multispectral Optoacoustic Tomography for 3-Dimensional Reconstruction of Skin Tumors: A Further Evaluation with Histopathologic Correlation. J Invest Dermatol. 2019 Feb;139(2):481-485. doi: 10.1016/j.jid.2018.08.014. Epub 2018 Sep 15. PMID: 30227137.

Tham HP, Xu K, Lim WQ, Chen H, Zheng M, Thng TGS, Venkatraman SS, Xu C, Zhao Y. Microneedle-Assisted Topical Delivery of Photodynamically Active Mesoporous Formulation for Combination Therapy of Deep-Seated Melanoma. ACS Nano. 2018 Dec 26;12(12):11936-11948. doi: 10.1021/acsnano.8b03007. Epub 2018 Nov 16. PMID: 30444343.

Toh JJH, Bhoi S, Tan VWD, Chuah SY, Jhingan A, Kong AWK, Thng STG. Automated scoring of vitiligo using superpixel-generated computerized digital image analysis of clinical photographs: a novel and consistent way to score vitiligo. Br J Dermatol. 2018 Jul;179(1):220-221. doi: 10.1111/bjd.16563. Epub 2018 May 10. PMID: 29573393.

Gan EY, Kong YL, Tan WD, Thng ST, Goh BK. Twelve-month and sixty-month outcomes of noncultured cellular grafting for vitiligo. J Am Acad Dermatol. 2016 Sep;75(3):564-571. doi: 10.1016/j.jaad.2016.04.007. Epub 2016 May 12. PMID: 27180264.

Attia ABE, Chuah SY, Razansky D, Ho CJH, Malempati P, Dinish US, Bi R, Fu CY, Ford SJ, Lee JS, Tan MWP, Olivo M, Thng STG. Noninvasive real-time characterization of non-melanoma skin cancers with handheld optoacoustic probes. Photoacoustics. 2017 Jun 4;7:20-26. doi: 10.1016/j.pacs.2017.05.003. PMID: 28652976; PMCID: PMC5473546.


A*STAR Open Access Repository