Asian Skin Biobank

Asian Skin Biobank header

We know Asian Skin

Located in the heart of Asia, the Asian Skin Biobank (ASB) specialises in a diverse range of Asian skin. 

The ASB delivers quality human skin samples and services to support skin research in Singapore and worldwide. The ASB also develops in vitro skin models and assays for collaborative research projects with academia and industry. 

Our mission is to improve skin health and quality of life for all in Asia.

The ASB is a registered Tissue Bank, compliant with the Human Biomedical Research Act 2015 and the Human Tissue Framework in Singapore. 

Our capabilities

asian skin cells asian skin biobank v3

Asian Skin cells

We collect surgical waste skin tissues from healthy female and male donors of various Asian ethnicity, age groups, and body sites, from which primary skin cells are derived. The Asian Skin Biobank provides high quality dermal fibroblasts, epidermal keratinocytes and melanocytes that are fully authenticated, contamination-free, negative for infectious agents, and from early-passage cultures.

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3D human skin models asian skin biobank v3

3d human skin models

The Asian Skin Biobank provides robust in vitro 3D reconstructed human skin models, made with donor-matched fibroblasts and keratinocytes in less than 14 days. We also develop new Asian skin models, such as skin organoids and 3D printed skins. Fresh ex vivo skin explants, OCT- frozen, and Formalin-Fixed Paraffin-Embedded skin tissues are also available.

Request skin models




skin cell assays asian skin biobank v3

skin cell assays

The Asian Skin Biobank offers 2D and 3D skin cell assays which are suitable for a wide range of research and test applications. We provide a set of standardized or tailor-made assays to assess downstream effects of external factors (UV, oxidative stress, drug treatment) on skin biology, viability, differentiation, ageing, inflammation, pigmentation etc.

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training and support asian skin biobank v3

Training & support

The Asian Skin Biobank trains scientists to isolate and expand skin cells following Good Laboratory Practice standards. We support researchers to derive rare subpopulations of skin cells including immune cells, follicular cells, and sebocytes. We also offer immunohistochemistry and immunofluorescence services on frozen or fixed skin samples.

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Quality assurance and facilities

All samples are collected, processed and distributed upon Institutional Review Board (IRB) approval. Donors provided voluntary and informed consent for use of the samples in future research studies.

Handling and processing of skin samples are carried out in a lean 10K lab, accessible only to trained personnel, with high GLP/ISO standards, SOPs and an integrated Laboratory Inventory Management System (LIMS). 

Collaborative research, consultancy, fee for service and training options are welcomed.

Request human skin samples or models


  1. Email us to discuss your research needs
  2. Submit an application form to request skin samples (https://srisasianskinbiobank.weebly.com)
  3. Provide your ethics application and approval letter

Non-identifiable donor information, sample characteristics and specifications, as well as culture conditions may be provided.

Press

The ASB has contributed to a range of research studies in skin, biology and diseases, skin immunity, inflammation, ageing, stem cells, and 3D in vitro models, including the following selected publications:

Koh R, Szeverényi I, Lee B, Denil SLIJ, Lim SYJ, Benny PA, Grasset N, Tan BK, Lane EB. Oxygen-Mediated Control of the Keratinocyte Proliferation-Differentiation Axis. J Invest Dermatol. 2020 Jan;140(1):235-238.e3. doi: 10.1016/j.jid.2019.05.030. Epub 2019 Jul 5. PMID: 31283927.

Liew WC, Sundaram GM, Quah S, Lum GG, Tan JSL, Ramalingam R, Common JEA, Tang MBY, Lane EB, Thng STG, Sampath P. Belinostat resolves skin barrier defects in atopic dermatitis by targeting the dysregulated miR-335:SOX6 axis. J Allergy Clin Immunol. 2020 Sep;146(3):606-620.e12. doi: 10.1016/j.jaci.2020.02.007. Epub 2020 Feb 21. PMID: 32088305.

Wong CW, LeGrand CF, Kinnear BF, Sobota RM, Ramalingam R, Dye DE, Raghunath M, Lane EB, Coombe DR. In Vitro Expansion of Keratinocytes on Human Dermal Fibroblast-Derived Matrix Retains Their Stem-Like Characteristics. Sci Rep. 2019 Dec 6;9(1):18561. doi: 10.1038/s41598-019-54793-9. PMID: 31811191; PMCID: PMC6897920.

Tan JJY, Common JE, Wu C, Ho PCL, Kang L. Keratinocytes maintain compartmentalization between dermal papilla and fibroblasts in 3D heterotypic tri-cultures. Cell Prolif. 2019 Sep;52(5):e12668. doi: 10.1111/cpr.12668. Epub 2019 Aug 5. PMID: 31379046; PMCID: PMC6797517.

Tan CL, Chin T, Tan CYR, Rovito HA, Quek LS, Oblong JE, Bellanger S. Nicotinamide Metabolism Modulates the Proliferation/Differentiation Balance and Senescence of Human Primary Keratinocytes. J Invest Dermatol. 2019 Aug;139(8):1638-1647.e3. doi: 10.1016/j.jid.2019.02.005. Epub 2019 Feb 15. PMID: 30776433. A*STAR Open Access Repository

Chourabi M, Liew MS, Lim S, H'mida-Ben Brahim D, Boussofara L, Dai L, Wong PM, Foo JN, Sriha B, Robinson KS, Denil S, Common JE, Mamaï O, Ben Khalifa Y, Bollen M, Liu J, Denguezli M, Bonnard C, Saad A, Reversade B. ENPP1 Mutation Causes Recessive Cole Disease by Altering Melanogenesis. J Invest Dermatol. 2018 Feb;138(2):291-300. doi: 10.1016/j.jid.2017.08.045. Epub 2017 Sep 28. PMID: 28964717.

Zhong FL, Mamaï O, Sborgi L, Boussofara L, Hopkins R, Robinson K, Szeverényi I, Takeichi T, Balaji R, Lau A, Tye H, Roy K, Bonnard C, Ahl PJ, Jones LA, Baker PJ, Lacina L, Otsuka A, Fournie PR, Malecaze F, Lane EB, Akiyama M, Kabashima K, Connolly JE, Masters SL, Soler VJ, Omar SS, McGrath JA, Nedelcu R, Gribaa M, Denguezli M, Saad A, Hiller S, Reversade B. Germline NLRP1 Mutations Cause Skin Inflammatory and Cancer Susceptibility Syndromes via Inflammasome Activation. Cell. 2016 Sep 22;167(1):187-202.e17. doi: 10.1016/j.cell.2016.09.001. PMID: 27662089.

Contact us

For more information on the Asian Skin Biobank, please contact Carine Bonnard.

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