Bioinformatics

PI/Head: Bernett LEE, Ph.D.
Email: Bernett_Lee@immunol.a-star.edu.sg
For more information regarding the SIgN Bioinfomatics Platform and services, please download a copy of our brochure here.

The Bioinformatics Platform uses state-of-the-art methods to analyse SIgN data and deliver pipelines and workflows to accelerate research

Overview

The Bioinformatics platform uses state-of-the-art methods to analyse SIgN data and deliver pipelines and workflows to accelerate research. The bioinformatics team handles not only the "usual" datasets, such as microarray and next-generation sequencing data, but also various heterogeneous datasets, such as those derived by flow cytometry, ELISA and Luminex assays and assesses the cross-correlation between these data(Figure 1).

Technologies and Applications

  • Accelrys Pipeline Pilot
  • Tibco Spotfire
  • MySQL
  • R
  • Metacore/GeneGo
  • Ingenuity Pathway Analysis
  • Oncomine
  • Transfac
  • Tuxedo suite for NGS analysis

Our equipment includes:

  • 31 node, 8 cores/node, 48Gb RAM/node linux cluster
  • 12 core, 64Gb RAM, 18 Tb RAID5 linux workstation
  • 6 core, 48Gb RAM, 35 Tb RAID5 Solaris database server and backup storage
unnamed (2)
Figure 1: Examples of data analysis
image7

Figure 2: Data analysis work flow