About A*STAR SIFBI

Biosolutions for Healthier Living and a Sustainable Future

We are Singapore’s innovation engine for nutrition and biotechnology, combining synthetic biology, food and sensory science, nutrition and human evidence to turn discovery into solutions that improve health and wellbeing in Asia.

Automated biological engineering laboratory at A*STAR SIFBI
DISCOVERY TRANSLATION IMPACT

Our Vision

Innovation engine driven by biosolutions, advancing health and wellbeing in Asia.

Our Mission

01

Sustain Singapore’s attractiveness as a global innovation hub for FMCG and ingredient solutions companies.

 
02

Support national priorities in bioeconomy, food resilience, and healthy longevity.

Our Strategic Pillars

Two pillars. One connected innovation engine.

 

Our two strategic pillars connect sustainable ingredient innovation with nutrition and digestive health—building the science and evidence needed to deliver meaningful solutions for consumers in Asia.

STRATEGIC Pillar 01

Sustainable Value-Added Ingredients Innovation

Create high-value bio-based ingredients through strain and enzyme engineering, then develop scalable processes that move promising technologies towards manufacture.

Strain engineering

Engineer microbial cell factories and novel pathways for high-value ingredients using data-guided design, genome engineering and automated construction.

 
Microbial cell factories Terpenoids Lipids platform Alternative feedstocks Industrialized strains C1–C3 feedstock engineering Biofoundry
Enzyme engineering

Discover, screen and optimise enzymes through high-throughput experimentation, molecular modelling and machine-learning-enabled automation.

 
Enzyme screening Molecular design Characterisation Formulation Integrated microbial engineering
Bioprocess and downstream processing

Build scalable, economical processes from laboratory development to pilot validation and industry transfer, including recovery and purification.

 
Process intensification Fermentation up to 10,000 L Separation Purification Biocatalysis Scale-up

STRATEGIC Pillar 02

Nutritional Solutions and Digestive Health for Asians

Develop consumer-driven, science-backed solutions by connecting food and sensory science with microbiome, digestive physiology and human nutrition research.

Flavour and sensory perception

Understand oronasal sensory physiology, flavour and aroma perception to design products that consumers enjoy and adopt.

 
Oronasal physiology Flavour perception Aroma perception Consumer acceptance
Food matrix and nutrient release

Design food structures that control flavour, aroma and nutrient release for targeted consumer and health outcomes.

 
Food structure Nutrient release Flavour delivery Targeted outcomes
Eating behaviour and cognition

Study chewing, appetite, ingestive behaviour and cognition through sensory and experimental nutrition research.

 
Chewing Appetite Ingestive behaviour Cognition
Gut microbiome

Use gut microbiome and multi-omics data to discover biomarkers, ingredients and responder-specific opportunities.

 
Gut microbiome Multi-omics Biomarkers Responder stratification
Digestive & human modelling

Evaluate ingredient and product performance using dynamic in vitro gut models such as SHIME® and in silico modelling.

 
SHIME® In vitro digestion In silico modelling Product performance
Experimental nutrition

Translate insights through consumer research, cohort studies and clinical intervention studies in Asian populations.

 
Consumer studies Cohort studies Clinical interventions Asian populations

Applications

From high-value biosolutions to industrial applications
 

Our strain, enzyme and bioprocess capabilities support applications across health, nutrition, consumer products, food, materials and industrial biotechnology.

 
Consumer care
 
Nutrition
 
Materials and other specialty chemicals
 
Food
 
Agrochemicals
 
Therapeutics

Integrated Across the Value Chain

SIFBI’s strategic pillars drive innovation across the value chain
 

From raw ingredients and ingredient solutions to consumer products and validated health outcomes.

Raw ingredients & ingredient solutions Product and brand owners
 
01 Discover
Ingredient and enzyme discovery

Discover functional ingredients and enabling enzymes, including proteins, lipids, bioactives and biotics.

 
02 Engineer and scale
Biotransformation, downstream processing and scale-up

Develop strains, engineer enzymes, optimise fermentation and build downstream processes for scalable production.

 
03 Design
Food and sensory science

Translate ingredients into consumer-relevant products through sensory physiology and food material design.

 
04 Validate
Clinical nutrition and validation

Assess nutritional and sensory benefits through in vitro models, in vivo research and human studies.

Strategic Pillar 1
Sustainable Value-Added Ingredients Innovation
Strategic Pillar 2
Nutritional Solutions and Digestive Health for Asians
RIE2030
Strategic Priorities
BIO
Bioeconomy
HL
Precision health · Healthy longevity

Partner with SIFBI

Let’s turn your challenge into an innovation pathway

Work with our multidisciplinary teams to discover, develop, scale and validate science-driven solutions for the bioeconomy, nutrition and healthy longevity.

Co-development Technology translation Scale-up and validation