4 Papers Accepted at AI 4 X 2025

Congratulations to the following scientists from A*STAR Centre for Frontier AI Research (A*STAR CFAR) on having their papers accepted at the AI for Science (AI 4 X) Conference 2025:

Prof Ivor Tsang, Director, Distinguished Principal Scientist
Dr Qian Hangwei, Scientist
Dr Yao Yinghua, Scientist
Dr Zhang Jie, Scientist

List of accepted papers:

1.	Sparse Autoencoders Reveal Interpretable Structure in Small Gene Language Models Haoxiang Guan, Jiyan He, Jie Zhang Our study demonstrates that sparse autoencoders (SAEs) can extract biologically meaningful representations from small gene language models, revealing structured features at both the nucleotide and regulatory element levels.
2.	RetiRAG: A Retrieval-Augmented Generation Framework for Specialized Ophthalmology Applications Ting Xu, Siyani Chen, Meng Wang, Wenbin Liao, Jie Zhang, Tian Lin, Huazhu Fu, Dianbo Liu, Haoyu Chen, Ching-Yu Cheng This study developed RetiRAG, a retrieval-augmented language model for ophthalmology. RetiRAG highlights the potential for compact, scalable large language models (LLMs) to achieve high performance in specialised medical domains while ensuring resource efficiency and safety.
3.	CogCommon: Enhancing Cross-Domain Knowledge Extraction with LLM-Assisted Commonality Discovery Chong Hu, Hangwei Qian, Ivor Tsang* The proposed CogCommon approach leverages cognitive linguistics to integrate cross-domain knowledge, improving entity extraction and connectivity in semiconductors while maintaining modularity, with notable gains in smaller LLMs.
4.	EVOL3D: A Large-Scale 3D Structure Dataset for Investigating Mutational Effects in Homologous Proteins Zhiqiang Zhong, Yinghua Yao, Davide Mottin, Jun Pang We introduce Evol3D, a large-scale open-source dataset comprising around 150K AlphaFold 3 predicted protein 3D structures derived from three extensively studied homologous protein families.

Jointly organised by the Institute for Functional Intelligent Materials (I-FIM) at the National University of Singapore (NUS), National Research Foundation of Singapore (NRF) and DSO National Laboratories, the AI 4 X conference is premier gathering of researchers who revolutionise Natural Science with Artificial Intelligence (AI). The inaugural conference will be held from 8^th – 11^th July at University Town, NUS.

Learn more about AI 4 X 2025.

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4 Papers Accepted at AI 4 X 2025

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