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BTI Past Research Highlights

2021_06 Front Chem_Zach Pang Thumbnail

Fast and semi-automatic workflow to analyse monoclonal antibody glycopeptides

Team Photo for Scientific Reports 2018 8: 11608

CONSERVATION OF ONCOFETAL ANTIGENS ON HUMAN EMBRYONIC STEM CELLS ENABLES DISCOVERY OF MONOCLONAL ANTIBODIES AGAINST CANCER

2021_05 Wei Thumbnail

An efficient and simplified purification workflow to accelerate viral vaccines development and production

2021_04 Dave Grp Pic

A novel anchoring domain for surface display on lactic acid bacteria

2021_03 Rachel Zhai_Scientific Reports_Thumbnail

Illuminating cells for improved health: label-free autofluorescence method for enhancing quality of cell therapy

2021_03 Anal Chem. 2020 92(23)15323-15335

Higher 3D resolution of oligosaccharide structures can now be obtained using ion-mobility mass spectrometry

2021_02 Thumbnail_Biotechnology Journal e2000267

When less is more: Disabling genes for cells to make more protein drugs

2021_01 Group Photo_Stem Cell Reports 16(1) 182-197 (watermarked)

Designer Blood for All, Now Manufacturable

Team Photo for Scientific Data 2020 7(1): 263

Chinese Hamster Ovary Spectral Library for Biopharmaceutical and Bioprocessing

2020_08 Alan Thumbnail

Beauty in One Pot: Integrating Production of High-Quality Heart Cells

2020_08 Wei Thumbnail

Discovery of novel mechanism to guide bispecific antibody purification

2020_08 Hong Hwa Thumbnail2

Dun1, a Chk2-related Kinase, Is the Central Regulator of DNA Damage Signaling

Team Photo for Cells 2020 9(3): 585

ASK1 Relays Death Signals in T-Cell Receptor Mediated Apoptosis of Thymocytes

2020_08 Andre Thumbnail

Annexin A2-Specific Chimeric Antigen Receptor T Cells Against Ovarian Cancer

2020_07 Say Kong thumbnail

High titer stable production of recombinant erythropoietin in HEK293

Summary Image of Stem Cell Research 2020 44: 101738

Human Mesenchymal Stem Cell Therapy for Cartilage Repair: Review on Isolation, Expansion, and Constructs

2020_07 Shengli Group Photo

What fuels NK cells when they kill their targets

2020_02 Jia Tong Group Photo

Dok3–protein phosphatase 1 interaction attenuates Card9 signaling and neutrophil-dependent antifungal immunity

2020_02 Heng Liang Group Photo 2

In vivo surveillance and elimination of teratoma‐forming human embryonic stem cells with monoclonal antibody 2448 targeting annexin A2

2020_02 Pao Chun Group Photo

Attenuated glutamine synthetase as a selection marker in CHO cells to efficiently isolate highly productive stable cells for the production of antibodies and other biologics

2019_09 Steve Group Photo

Sub-confluent culture of human mesenchymal stromal cells on biodegradable polycaprolactone microcarriers enhances bone healing of rat calvarial defect

2019_08 Hock Chuan Group Photo

An LC–MS-based lipidomics pre-processing framework underpins rapid hypothesis generation towards CHO systems biotechnology

Team Photo for Journal of Autoimmunity 2017 89: 53-62

EXCESSIVE INTERFERON-Α SIGNALING IN AUTOIMMUNITY ALTERS GLYCOSPHINGOLIPID PROCESSING IN B CELLS

2019_09 Matthew Group Photo

GlycopeptideGraphMS: Improved Glycopeptide Detection and Identification by Exploiting Graph Theoretical Patterns in Mass and Retention Time

Team Photo of Scientific Reports 2017 6: 35110

Lipidomic Profiling of Lung Pleural Effusion Identifies Unique Metabotype for EGFR-Mutants in Non-Small Cell Lung Cancer

Team Photo for Cell Death and Differentiation 2017 24(3): 546-558

EXCESS REACTIVE OXYGEN SPECIES PRODUCTION MEDIATES MONOCLONAL ANTIBODY-INDUCED HUMAN EMBRYONIC STEM CELL DEATH VIA ONCOSIS

Team Photo for Scientific Reports 2017 7(1): 15721

Genome-Scale Modeling and Transcriptome Analysis of Leuconostoc Mesenteroides Unravel the Redox Governed Metabolic States in Obligate Heterofermentative Lactic acid Bacteria

Team Photo of PLoS One 2016 11(3): e0152112

Characterization of a Polyethylene Glycol-Amphotericin B Conjugate Loaded with Free AMB for Improved Antifungal Efficacy

Team Photo for Scientific Reports 2017 7(1): 16686

TREHALOSE SIGNIFICANTLY ENHANCES THE RECOVERY OF SERUM AND SERUM EXOSOMAL MIRNA FROM A PAPERBASED MATRIX

Team Photo for Scientific Reports 2017 (7) 45216

EVALUATION AND USE OF DISACCHARIDES AS ENERGY SOURCE IN PROTEIN-FREE MAMMALIAN CELL CULTURES

Team Photo for Oncotarget 2017 9(17): 13206-13221

Targeting of Embryonic Annexin A2 Expressed on Ovarian and Breast Cancer by the Novel Monoclonal Antibody 2448

Team Photo for Scientific Reports 2016 6: 31068

Genome-Wide Transcriptome and Binding Sites Analyses Identify Early Fox Expressions for Enhancing Cardiomyogenesis Efficiency of HESC Cultures

Team Photo for Cytotherapy 2016 18: 740-753

Expansion in Microcarrier-Spinner Cultures Improves the Chondrogenic Potential of Human Early Mesenchymal Stem Cells