Guide RNA designer tools

Name of software Guide RNA designer tools 
Purpose Design of gRNAs for CRISPR interventions
Name of Contact Chew Wei Leong
Email of technical contact
Summary of software function

These are CRISPR gRNA designers. Given a target sequence or genome, the software generates all possible gRNA candidates, evaluates them for specificity (based on edit distance / mismatches with host DNA/RNA sequences), and predicts on-target editing efficiency. These are modular and can plug in with other predictive modules ad hoc.

Patents :
GIS/Z/13167; Guide RNA designer for C-to-G base editors (CGBE)
GIS/Z/12079; CRISPR-Cas13 guide RNA designer

These guide RNA designer tools are freely available for academic research. Commercial usage requires a license.