NDRquant

Name of software NDRquant 
Purpose Quantification the content of circulating tumor DNA (ctDNA) in plasma cell-free DNA
Name of Contact Anders Skanderup
Email of technical contact skanderupamj@gis.a-star.edu.sg
Summary of software function

NDRquant is a method for quantification the content of circulating tumor DNA (ctDNA) in plasma cell-free DNA (cfDNA) based on tissue-specific cfDNA degradation of nucleosome depleted regions (NDR).

NDRquant is freely available for academic use (https://github.com/skandlab/NDRquant). Commercial usage requires a license.
Publications describing software & its application Zhu, G. et al. Tissue-specific cell-free DNA degradation quantifies circulating tumor DNA burden. Nat Commun 12, 2229 (2021). https://doi.org/10.1038/s41467-021-22463-y PMID: 33850132

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