Stuart Alexander COOK

 

RESEARCH

Genetic basis of cardiovascular disease, disease mechanisms, CMR, novel diagnostics, therapeutic target development, ICCs, heart failure.

Selected Publications

• Herman, D. S. et al. Truncations of titin causing dilated cardiomyopathy. N. Engl. J. Med. 366, 619–628 (2012). Abstract
• Ware, J. S., Roberts, A. M. & Cook, S. A. Next generation sequencing for clinical diagnostics and personalised medicine: implications for the next generation cardiologist. Heart 98, 276–281 (2011). Abstract
• McDermott-Roe, C. et al. Endonuclease G is a novel determinant of cardiac hypertrophy and mitochondrial function. Nature 478, 114–118 (2011). Abstract
• Heinig, M. et al. A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk. Nature 467, 460–464 (2010). Abstract
• Petretto, E. et al. Integrated genomic approaches implicate osteoglycin (Ogn) in the regulation of left ventricular mass. Nat Genet 40, 546–552 (2008). Abstract