DAN Yock Young

Yock Young DAN

Associate Professor
Chair, University Medicine Cluster, NUHS
Head, Dept of Medicine, NUS
Senior Consultant, Division of Gastroenterology and Hepatology
Adjunct, Cancer Science Institute, NUS

yock_young_dan@nuhs.edu.sg

RESEARCH

Cost effectiveness of clinical treatment
Liver Stem Cells and their therapeutic applications
Liver cancer
Fatty Liver and Metabolic Liver Disease

Selected Publications

  • Lin JS, Zhou L, Sagayaraj A, Jumat NH, Choolani M, Chan JK, Biswas A, Wong PC, Lim SG, Dan YY. Hepatic differentiation of Human Amniotic Epithelial cells and in vivo therapeutic effect on animal model of cirrhosis. J Gastroenterol Hepatol. 2015 May 14. doi: 10.1111/jgh.12991. Abstract
  • Tan CY, Lai RC, Wong W, Dan YY, Lim SK, Ho HK. Mesenchymal stem cell-derived exosomes promote hepatic regeneration in drug-induced liver injury models. Stem Cell Res Ther. 2014 Jun 10;5(3):76. doi: 10.1186/scrt465 Abstract
  • Dan YY, Lim SG. Commentary: vitamin D deficiency and liver cancer - cause, effect or myth? Aliment Pharmacol Ther. 2014 Jun;39(12):1429. doi: 10.1111/apt.12768 Abstract
  • Yong KJ, Gao C, Lim JS, Yan B, Yang H, Dimitrov T, Kawasaki A, Ong CW, Wong KF, Lee S, Ravikumar S, Srivastava S, Tian X, Poon RT, Fan ST, Luk JM, Dan YY, Salto-Tellez M, Chai L, Tenen DG. Oncofetal gene SALL4 in aggressive hepatocellular carcinoma. N Engl J Med. 2013 Jun 13;368(24):2266-76 Abstract
  • Dan YY. Clinical uses of liver stem cells. Methods Mol Biol. 2012;826:11-23 Abstract
  • Lim SG, Aung MO, Mak B, Sutedja D, Lee YM, Lee GH, Fernandes M, Low HC, Lai V, Dan YY Clinical outcomes of lamivudine-adefovir therapy in chronic hepatitis B cirrhosis. J Clin Gastroenterol. 2011 Oct;45(9):818-23 Abstract
  • Lim LG, Tan XX, Woo SJ, Dan YY, Lee YM, Lai V, Lim SG Risk factors for mortality in cirrhotic patients with sepsis. Hepatol Int. 2011 Feb 13 Abstract
  • Riehle KJ, Dan YY, Campbell JS, Fausto N.New concepts in liver regeneration. J Gastroenterol Hepatol. 2011 Jan;26 Suppl 1:203-12 Abstract
  • Dan YY, Yeoh GC. Liver stem cells: a scientific and clinical perspective. J Gastroenterol Hepatol. 2008 May;23(5):687-98 Abstract
  • Dan YY, Riehle KJ, Lazaro C, Teoh N, Haque J, Campbell JS, et al. Isolation of multipotent progenitor cells from human fetal liver capable of differentiating into liver and mesenchymal lineages. Proceedings of the National Academy of Sciences of the United States of America. 2006;103(26):9912-7 Abstract