Bioinformatics Institute (BII)
The Bioinformatics Institute (BII) was set up by the Agency for Science, Technology and Research (A*STAR) in July 2001; it was re-launched with a strong scientific program in 2007. Located in the Biopolis in Singapore, BII is conceived as the computational biology research and postgraduate training institute as well as a national resource centre in bioinformatics within the Biomedical Research Council (BMRC) of A*STAR.
The Bioinformatics Institute (BII) aims to understand the biomolecular mechanisms that underlie biomedical phenomena by developing sophisticated computational methods to support this discovery process from a secure and sustainable data hub to cross-disciplinary AI/ML analysis and data integration. We analyse a wide spectrum of biological and clinical data, including omics data (biomolecular sequences, expression profiles, epigenetics data), 3D structures of macromolecules, and biological tissue and macroscopic images from local and international academic, hospital and industry collaborators, public resources and from our own experiments. Our applied research diversifies into infectious diseases, computational toxicology, natural product research, precision medicine, cancer research, and drug discovery.
Research Divisions
Biomolecular Sequence to Functions
Biomolecular Structure to Mechanism
Cellular Image Informatics
Biomedical Data Hub
Events
Upcoming Events
Thursday, 03 October 2024
BII Seminar: Generative Design and Synthesis Prediction in Modern Drug Discovery
Speaker : Dr. Kenneth Atz, AI Scientist, Roche
Host: Dr. Sebastian Maurer-Stroh, Executive Director, BII
Friday, 20 September 2024
BII Science Unplugged 1
Justice Undone: Misapplied Science in Crime Investigations, by Olga Sirbu.
Serendipity in Science, by Pietro Aronica.
Tuesday, 01 October 2024
BII IBIDA course: Theoretical Aspects of Generative Models
Kindly reach out to the IBIDA course organizers via the following email, IBIDA@bii.a-star.edu.sg. Registration will close on 29th September 2024, 2359 SGT.
Thursday, 26 September 2024
BII Seminar: The Molecular Basis of RNA Virus Antigenic Shift
Bioinformatics Institute (BII) would like to invite you to attend the following seminar:
Speaker : Dr. David LV Bauer, Virologist, The Francis Crick Institute, UK
Thursday, 12 September 2024
BII Seminar: A whole-slide foundation model for digital pathology from real-world data,
Bioinformatics Institute (BII) would like to invite you to attend the following seminar:
Speaker : Dr Poon Hoifung, General Manager, Microsoft Health Futures
Monday, 12 August 2024
BII Seminar: AI for Predictive Analytics in the Development of Novel Therapeutics
Speaker : Dr James Lu, Distinguished AI Scientist, Genentech
Wednesday, 21 August 2024
Joint Seminar: BII-AI3 Special Interest Group of Digital Health Seminar
Speaker : Dr Dianbo Lu, Department of Biomedical Informatics, National University of Singapore
Monday, 26 August 2024
BII Seminar: Robust Spatial Biomarker Development Through AI-enabled Virtual Staining
Speaker : Dr Mai Chan Lau, Assistant Principal Investigator, Bioinformatics Institute (BII)
Friday, 26 July 2024
BII Seminar: Using simulation to understand the mechanism of transport and drug uptake in Peptide Transporters
Speaker : Prof Philip Biggin, Professor of Computational Biochemistry, Dept of Biochemistry, University of Oxford
Tuesday, 23 July 2024
BII Seminar: In silico enzymology - modelling enzymes using computational tools
Speaker : Prof Sam Hay, Computational Theoretical Chemistry, University of Manchester
Wednesday, 26 June 2024
BII Seminar: Targeting an oncofetal protein SALL4 in cancer
Speaker : Dr Li Chai, Pathology/Transfusion Medicine, Brigham and Women’s Hospital/Harvard Medical School
Tuesday, 18 June 2024
BII Seminar: Targeting Energy of Life for Eradication of antibiotic-resistant bacterial pathogens
Speaker : Prof. Dr. Gerhard Grüber, School of Biological Sciences, Nanyang Technological University, Singapore
Tuesday, 25 June 2024
BII Seminar: Developing new CADD methods for Drug Discovery and Relocalization
Speaker : Prof Zhu Weiliang, Principal Investigator, Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CAS)
Friday, 07 June 2024
BII Event: BII Scientific Conference 2024
Please go to the page for the updated program.
BII Scientific Conference 2024
Tuesday, 04 June 2024
BII Seminar: Artificial Intelligent Agents based Automation to Accelerate Drug Discovery
Speaker: Dr Gaurav Chopra, Departments of Chemistry and Computer Science, Purdue University
Zoom Meeting : https://zoom.us/j/99204867610?pwd=M0NMdDgrQTVmaTVyeC91WUVKMyszZz09
Meeting ID : 992 0486 7610
Passcode : 417187
Monday, 03 June 2024
BII Seminar: Applied Artificial Intelligence in Drug Discovery for Prospective De Novo Ligand Design:
Speaker : Prof. Dr. Gisbert Schneider, Computer-Assisted Drug Design, ETH Zurich
There will be a networking tea reception after the seminar
Please register via the following links: Registration Form
Wednesday, 27 March 2024
BII Seminar: Part 2 - Applications of Variational Quantum Algorithms in computational Chemistry and Biology
Speaker : Dr Kalyan Dasgupta, IBM Research India
Title : Applications of Variational Quantum Algorithms in computational Chemistry and Biology
Friday, 05 April 2024
BII Seminar: The MIB BioSoftware Foundry: bespoke computational solutions for biotechnology and biomedical research
Speaker : Prof Rainer Breitling, Manchester Institute of Biotechnology, University of Manchester
Title : The MIB BioSoftware Foundry: bespoke computational solutions for biotechnology and biomedical research
Thursday, 25 April 2024
BII Seminar: 3D high-content screening spheroid model in autophagy
Speaker : Dr Janos Kriston-Vizi, Laboratory for Molecular Cell Biology (LMCB), University College London
Title : 3D high-content screening spheroid model in autophagy
Monday, 15 April 2024
BII Seminar: Structure, function, and regulation of G protein-coupled receptors
Speaker : Dr Arun K. Shukla, Dept of Biological Sciences and Engineering, Indian Institute of Technology
Title : Structure, function, and regulation of G protein-coupled receptors
A*STAR celebrates International Women's Day
From groundbreaking discoveries to cutting-edge research, our researchers are empowering the next generation of female science, technology, engineering and mathematics (STEM) leaders.
Get inspired by our #WomeninSTEM