Bioinformatics Institute (BII)

The Bioinformatics Institute (BII) was set up by the Agency for Science, Technology and Research (A*STAR) in July 2001; it was re-launched with a strong scientific program in 2007. Located in the Biopolis in Singapore, BII is conceived as the computational biology research and postgraduate training institute as well as a national resource centre in bioinformatics within the Biomedical Research Council (BMRC) of A*STAR.

The Bioinformatics Institute (BII) aims to understand the biomolecular mechanisms that underlie biomedical phenomena by developing sophisticated computational methods to support this discovery process from a secure and sustainable data hub to cross-disciplinary AI/ML analysis and data integration. We analyse a wide spectrum of biological and clinical data, including omics data (biomolecular sequences, expression profiles, epigenetics data), 3D structures of macromolecules, and biological tissue and macroscopic images from local and international academic, hospital and industry collaborators, public resources and from our own experiments. Our applied research diversifies into infectious diseases, computational toxicology, natural product research, precision medicine, cancer research, and drug discovery.



Research Divisions

Biomolecular Sequence to Functions
Biomolecular Structure to Mechanism
Cellular Image Informatics
Biomedical Data Hub

Events

Upcoming Events

16

Oct

BII Seminar: Beyond transcriptomics, mass spectrometry based proteomics, from bulk to single cell analysis

Cysteine Meeting Room, Matrix Level 7

24

Oct

BII Seminar: The Search for a Novel Pyruvate Kinase Activator - From a HTS Hit via an Impurity to the Discovery of a Lead Series

Cysteine Meeting Room, Matrix Level 7

30

Oct

BII Seminar: Conformational Sampling, Thermodynamic Landscapes and Chemical Intuitions: Computational Routes to the Molecular Mechanisms of Biomolecules

Cysteine Meeting Room, Matrix Level 7

7

Nov

BII Seminar: High-Resolution Molecular Dynamics Simulations for Biophysics

Cysteine Meeting Room, Matrix Level 7